Introduction This study used Lekgotla discussion with Batlokwa women to formulate and verify the strategies to empower the women with traditional and cultural dysmenorrhea or pain period knowledge. The Lekgotla discussion is an open forum in which indigenous communities in Sub-Saharan Africa use to debate and reach agreements on community raised issues. It has the potential to identify issues that affect community day-to-day lives and reach consensus to effect changes. Purpose To present Lekgotla discussion workshop as a decolonized qualitative research methodology. Methods The study was qualitative, using a Lekgotla discussion process among women with a variety of experience in both Indigenous and Western dysmenorrhea knowledge. Participants were purposively selected to participate in a Lekgotla discussion. The snowballing was also used, whereby the recruited participants were asked to assist in identifying and referring potential participants to the researcher, who contacted them for potential inclusion in the study. The process was repeated until a required sample was reached. A facilitator was selected by the participants to facilitate the discussion and summarizes the inputs once all the participants have raised their ideas and there was no newer information was shared. The debates and dialogues were analysed by the researcher and experts using content data analysis. Results The Lekgotla discussion followed a workshop process and was divided into four steps: 1) Arrival and Welcome, 2) Engaging participants, 3) Reaching consensus on the strategies to empower Batlokwa women with dysmenorrhea knowledge, 4) Verification and refinement of the strategies to empower Batlokwa women with dysmenorrhea knowledge. Conclusion The success of applying the process of Lekgotla discussion proved that the indigenous epistemologies are increasingly accepted to achieve research objectives.