The imprecision of micronutrient requirement values: the example of vitamin D

Fernandes, Tito Horácio; Bell, Victoria

doi:10.1111/1750-3841.16889

Cited by 3 publications

(1 citation statement)

References 123 publications

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“…Because no easy and cost-effective treatment has yet been found, recent efforts have been directed toward nutritional interventions to reduce ill health and improve the quality of life for SCD patients. However, there are limitations within the current scope of the recommended daily allowances and dietary reference intakes for world populations, and nutrient density has also been under consideration [ 151 ]. This makes it even more challenging to establish specific nutritional requirements for sickle cell patients.…”

Section: Nutritional Perspectives In Sickle Cell Diseasementioning

confidence: 99%

Sickle Cell Disease Update: New Treatments and Challenging Nutritional Interventions

Bell,

Varzakas,

Psaltopoulou

et al. 2024

Nutrients

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Sickle cell disease (SCD), a distinctive and often overlooked illness in the 21st century, is a congenital blood disorder characterized by considerable phenotypic diversity. It comprises a group of disorders, with sickle cell anemia (SCA) being the most prevalent and serious genotype. Although there have been some systematic reviews of global data, worldwide statistics regarding SCD prevalence, morbidity, and mortality remain scarce. In developed countries with a lower number of sickle cell patients, cutting-edge technologies have led to the development of new treatments. However, in developing settings where sickle cell disease (SCD) is more prevalent, medical management, rather than a cure, still relies on the use of hydroxyurea, blood transfusions, and analgesics. This is a disease that affects red blood cells, consequently affecting most organs in diverse manners. We discuss its etiology and the advent of new technologies, but the aim of this study is to understand the various types of nutrition-related studies involving individuals suffering from SCD, particularly in Africa. The interplay of the environment, food, gut microbiota, along with their respective genomes collectively known as the gut microbiome, and host metabolism is responsible for mediating host metabolic phenotypes and modulating gut microbiota. In addition, it serves the purpose of providing essential nutrients. Moreover, it engages in direct interactions with host homeostasis and the immune system, as well as indirect interactions via metabolites. Nutrition interventions and nutritional care are mechanisms for addressing increased nutrient expenditures and are important aspects of supportive management for patients with SCD. Underprivileged areas in Sub-Saharan Africa should be accompanied by efforts to define and promote of the nutritional aspects of SCD. Their importance is key to maintaining well-being and quality of life, especially because new technologies and products remain limited, while the use of native medicinal plant resources is acknowledged.

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Section: Nutritional Perspectives In Sickle Cell Diseasementioning

confidence: 99%

Sickle Cell Disease Update: New Treatments and Challenging Nutritional Interventions

Bell,

Varzakas,

Psaltopoulou

et al. 2024

Nutrients

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Two stages data mining analytics for food intentional and behavioral recommendations

Liao,

Widowati,

Liao

2024

IDA

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A recommender system is an information filtering system used to predict a user’s rating or preference for an item. Dietary preferences are often influenced by various etiquettes and culture, such as appetite, the selection of ingredients, menu development, cooking methods, choice of tableware, seating arrangement of diners, order of eating, etc. Food delivery service is a courier service in that delivers food to customers by restaurants, stores, or independent delivery companies. With the continuous advances in information systems and data science, recommender systems are gradually developing towards to intentional and behavioral recommendations. Behavioral recommendation is an extension of peer-to-peer recommendation, where merchants find the people who want to buy the product and deliver it. Intentional recommendation is a mindset that seeks to understand the life of consumers; by continuously collecting information about their actions on the internet and displaying events and information that match the life and purchase preferences of consumers. This study considers that data targeting is a method by which food delivery service platforms can understand consumers’ dietary preferences and individual lifestyles so that the food delivery service platform can effectively recommend food to the consumer. Thus, this study implements two stages data mining analytics, including clustering analysis and association rules, to investigate Taiwanese food consumers (n= 2,138) to investigate dietary and food delivery services behaviors and preferences to find knowledge profiles/patterns/rules for food intentional and behavioral recommendations. Finally, discussion and implications are presented.

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The Policy of Compulsory Large-Scale Food Fortification in Sub-Saharan Africa

Bell,

Rodrigues,

Ferrão

et al. 2024

Foods

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Food fortification with micronutrients was initially justified in developed countries by a lack of availability of micronutrients in staple crops, mainly due to soil exhaustion. However, in Sub-Saharan arable lands, soil fatigue is not predominant, and communities consume mostly home-grown, organic, non-processed crops. Sub-Saharan food systems are nevertheless deeply entwined with food insecurity, driver of illnesses. Family production can promote subsistence, food stability, and self-sufficiency, the main SSA setback being the vicious cycle of poverty and the lack of dietary variety, contributing to malnutrition. Poverty reduction and women’s education are significant strategies for reducing child and adolescent undernourishment. Fortification of foods consumed daily by individuals makes sense and can minimize, if not entirely, eliminate deficiencies. Compulsory mass fortification of foods in Sub-Saharan Africa (SSA) with single micronutrients is, however, controversial since they work in synergy among each other and with the food matrix, for optimal absorption and metabolism. Since the causes of malnutrition are many, caused by diverse, unequal, and unjust food distribution, interrelated with political, social, cultural, or economic factors, education status of the population, season and climatic changes, and effectiveness of nutrition programs, just food fortification cannot solve the composite of all these elements. Further, compulsory fortification is excessive, unproductive, and likely harmful to human health, while many challenges remain in assessing the quality of available premixes. Furthermore, aiming at dietary diversification is the best approach of increasing trace element intake from commonly accessible and easily available food sources.

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The imprecision of micronutrient requirement values: the example of vitamin D

Cited by 3 publications

References 123 publications

Sickle Cell Disease Update: New Treatments and Challenging Nutritional Interventions

Sickle Cell Disease Update: New Treatments and Challenging Nutritional Interventions

Two stages data mining analytics for food intentional and behavioral recommendations

The Policy of Compulsory Large-Scale Food Fortification in Sub-Saharan Africa

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