2012
DOI: 10.1177/030089161209800405 View full text |Buy / Rent full text
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Abstract: Our novel approach might be helpful in clinical practice to predict breast cancer recurrence after surgery and might be adapted to be used in other malignancies as well.

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“…The mean age of the patients in the current study was 50.4 years (median = 51 years), consistent with other studies from Iran (9,(20)(21)(22) and also similar to that of Arab nations (23). In the current study, age was a significant factor for the survival of patients with BC in all models.…”
Section: Discussionsupporting
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“…The mean age of the patients in the current study was 50.4 years (median = 51 years), consistent with other studies from Iran (9,(20)(21)(22) and also similar to that of Arab nations (23). In the current study, age was a significant factor for the survival of patients with BC in all models.…”
Section: Discussionsupporting
“…There are many risk factors related to BC such as older age (55 years and above), genetic risk factors (BRCA1 and BRCA2), a positive family history, late menopause, early menstruation, using oral contraceptive pill (OCP), prolonged nulliparity, hormone replacement therapy (HRT) after menopause, obesity after menopause, and alcohol use (7,8). For metastasis of BC, there are several prognostic and predictive factors such as high tumor grade, lack of estrogen-receptor (ER) expression, over expression of human epidermal growth factor receptor 2 (HER2), and large tumor size (9). Despite some developments in systemic neoadjuvant or adjuvant therapies such as chemotherapy, radiotherapy, and hormonal therapy that can largely improve the prognosis of BC in recent years, the survival outcomes of patients with BC, especially in the elderly and the patients with long-term use of oral contraceptives, are still not optimistic (3).…”
Section: Introductionmentioning
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“…Metastasis [4,6,14,16,28,42], background of benign tumors [4], and age at diagnosis [4,5,16,INTRODUCTION 22,23,24,25,26,28,29,[32][33][34][35][36][37]39] were considered as the main factors in the survival analysis. Some studies emphasized on the factors such as hormone therapy (hormone receptor) [9,12,16,20,22,23,25,27,33,35,36,38], Her2 [9,11], grade [9,11,13,19,21,24,31,34,37,38], and lymph node involvement [11,19,…”
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