The Impact of Lifestyle Interventions in Breast Cancer Women after Completion of Primary Therapy: A Randomized Study

Abstract

IntroductionA number of risk factors have been identified in the pathogenesis of breast tumors. Among these, a great number of factors are attributed to the lifestyle (1). Reduced physical activity during cancer treatment can decrease the capacity for physical conditioning. The late effects of cancer and its treatment may consequently reduce physical activity in survivors. Breast cancer survivors with sedentary lifestyle have a higher risk for early mortality (2).About 20%-70% of breast cancer survivors may have sleep disturbance, which is twice of the general population. Sleep disturbance is more prevalent in women with breast cancer as compared to those with other cancers. They report new or worsening sleep disturbances with frequent nocturnal awakening. These problems are attributed to chemotherapy or endocrine treatments induced by early menopause (3, 4).Obesity and severe or extreme obesity is becoming a complex health problem that healthcare providers must begin to address within the oncology community (5). Studies have shown that obese women constitute a high-risk population for developing post-menopause breast cancer, and it is estimated that up to half of breast cancers that develop after menopause are attributed to obesity (6).One third of breast cancer patients report that Cancer-Related Fatigue (CRF) has an adverse impact on their daily living activities (7).Quality of Life is a concept that receives a lot of interest from healthcare providers. QoL measures have been used to help identify problems associated with cancer, medical management, and effectiveness of rehabilitative interventions, and to set healthcare policy (8). Breast Health 2017; 13: 94-99 DOI: 10.5152/tjbh.2017.3342 94 ABSTRACT Objective: Many breast cancer survivors have unmet physical and psychological needs. Therefore, current study aimed to evaluate the impact of a lifestyle interventions program on fatigue, quality of sleep, quality of life (QoL), and body mass index (BMI) in women with breast cancer. Materials and Methods:This randomized controlled trial study (RCT) was carried between 2012 and 2015, and included 80 women with breast cancer. They were divided into two groups via a random allocation process: 40 women were allocated to the lifestyle interventions group, and 40 to the control group. Women in the lifestyle group received dietary energy-restriction training and practiced supervised aerobic exercises for 45-60 minutes three times per week throughout 24 weeks and the control group continued their routine life.Results: Differences between the two groups were significantly high for those who participated in the intervention group; this group reported significantly less fatigue, less BMI, improved QoL and better quality of sleep as compared to the control group (p<0.05). Conclusion:Breast cancer survivors may physically and psychologically benefit from participating in a healthy lifestyle interventions program. This program can help relieve fatigue, maintain healthy BMI, improve QoL and enhance the quality of sleep in...

Evidence-Based Exercise Recommendations to Improve Mental Wellbeing in Women with Breast Cancer during Active Treatment: A Systematic Review and Meta-Analysis

“…The characteristics of study populations, intervention protocols and outcome measures and tools of measure are briefly described. All 57 selected studies, all RCTs in their design and published between 2001 and 2020 [ 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 , 77 , …”

“…In addition, we showed that concurrent training had a moderate positive effect on fatigue in women with breast cancer during active treatment (d = −0.59, 95% CI −0.79 to −0.38; I 2 = 62.5%). Furthermore, the eight trials employing different forms of intervention combining aerobic plus resistance interventions and aerobic or resistance training alone with a volume ≥150 min/week [ 32 , 33 , 40 , 41 , 46 , 47 , 51 , 67 ] demonstrated significant effect sizes across various fatigue scales. This is an important finding, because the beneficial effects of exercise interventions for both patients in active treatment (chemotherapy or radiation) and breast cancer survivors have been previously reported [ 82 , 83 , 84 , 85 ].…”

“…In this context, our results show that combining the aerobic and resistance interventions has beneficial effects on depression as compared to the control group (d= −0.37, 95% CI −0.72 to −0.02; I 2 = 70.7%). Furthermore, the three studies employing different forms of intervention combining aerobic plus resistance interventions and aerobic with a volume ≥ 150 min/week [ 40 , 41 , 67 ] and two studies employing similar forms of concurrent training with a volume < 150 min/week [ 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 ] demonstrated small to large effect sizes across the depression outcome. This finding is consistent with a recently published systematic review and meta-analysis that showed exercise significantly reduced depression in patients with breast cancer [ 91 ].…”

Impact of hot stone massage therapy on sleep quality in patients on maintenance hemodialysis: A randomized controlled trial

“…[17] In a research by Ghavami and Akyolcu, Cronbach's alpha reliability coefficient of the Persian version of PSQI scale (α) in the first measurement was 0.746 and it was calculated as 0.783 in the last evaluation. [18] Also, Farrahi Moghaddam et al . in 2012 realized Cronbach's alpha coefficient of 0.89% for the Persian version of PSQI.…”

Effect of self-care interventions on sleep quality in post-coronary artery bypass grafting patients: A single-center, randomized-controlled study

“…In the study of Ghavami and Akyolcu, Cronbach's alpha reliability coefficient of the Persian version of the PSQI scale (a) in the first measurement was calculated as 0.746 and it was 0.783 in the last measurement. [13] Furthermore, Farrahi Moghaddam et al [14] reported a sensitivity of 100%, specificity of 93%, and a Cronbach's alpha coefficient of 0.89% for the Persian version of the questionnaire. The PSQI and DIF were filled for all the participants before the intervention.…”