The impact of leprosy on health-related quality of life

Lustosa, Anselmo Alves; Nogueira, Lídya Tolstenko; Pedrosa, José Ivo dos Santos; Teles, João Batista Mendes; Campelo, Viriato

doi:10.1590/s0037-86822011000500019

Cited by 82 publications

(93 citation statements)

References 15 publications

(18 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Of the entire patient cohort, the age groups 14-33 and 34-53 years each represented one-third of the total patient population. This suggests that leprosy affects large number of individuals in the economically productive population, which causes high economic impacts due to their having to abstaining from work, caused by the development of permanent and physically disabling lesions 31,32 . Importantly, as these patients are not able to work, they have the right to seek sickness benefits and even disability retirement 33 .…”

Section: Discussionmentioning

confidence: 99%

Analysis of clinical data and T helper 1/T helper 2 responses in patients with different clinical forms of leprosy

Rodrigues

Ribeiro

Berber³

et al. 2017

Rev. Soc. Bras. Med. Trop.

View full text Add to dashboard Cite

Introduction: Currently, there are no laboratory tests or sensitive and specific molecular markers for the early diagnosis of leprosy. The aim of this study was to analyze the clinical characteristics of patients with leprosy and investigate their immunological profile, comparing this with the type of lesion and the presence or absence of a Bacillus Calmette-Guérin (BCG) vaccination scar. Methods: Statistical analyzes were performed by employing comparative tests (Pearson´s chi-square) to evaluate the variables in different clinical forms, considering significance at the 5% level. Results: The study identified a predominance of lepromatous leprosy (26.9%) in patients aged between 34-53 years. Caucasians predominantly had borderline tuberculoid (BT) clinical forms (42%); a predominance of males with borderline lepromatous (19%) and lepromatous leprosy (26.9%) forms was observed; and the presence of BCG vaccination scars (27.5%) and lower limb nerves were more affected (38%) predominantly in the BT clinical form. Significant differences were identified, which included hypochromic lesions predominantly in the BT clinical form (24%); diffuse-type lesions predominantly in the tuberculoid (TT) clinical form (28%); ill-defined lesion border dominance in lepromatous leprosy (LL) clinical forms (30%); an irregular lesion limit predominantly in LL clinical forms (32%); and a predominant Th1 immune response in the BT clinical form (41.7%). Conclusions: The evaluation of the immunological profile in leprosy patients may contribute to the more detailed diagnosis and possibly better characterization of the prognosis for these individuals.

show abstract

Section: Discussionmentioning

confidence: 99%

Analysis of clinical data and T helper 1/T helper 2 responses in patients with different clinical forms of leprosy

Rodrigues

Ribeiro

Berber³

et al. 2017

Rev. Soc. Bras. Med. Trop.

View full text Add to dashboard Cite

show abstract

“…A baixa escolaridade é um forte indicador de condições precárias de moradia, nutrição, higiene e acesso aos serviços de saúde (15) , fatores determinantes para a manutenção da cadeia de transmissão da hanseníase.…”

Section: Discussionunclassified

Incapacidades Físicas Em Hanseníase: Caracterização, Fatores Relacionados E Evolução

Ribeiro¹,

Lana²

2015

Cogitare Enferm.

View full text Add to dashboard Cite

RESUMO:Este estudo objetivou caracterizar os casos novos de hanseníase; analisar os aspectos socioeconômicos, demográficos, clínico-epidemiológicos e de acesso ao diagnóstico e tratamento relacionados à ocorrência de hanseníase com incapacidades físicas; e a evolução das incapacidades durante o tratamento. Foi realizada uma pesquisa de coorte retrospectiva na região ). There was a statistical relationship between the development of physical deformities and those affected by leprosy with lower levels of schooling, higher neural involvement, and greater difficulties in accessing the health unit, in addition to the maintenance of the degree of disability. There is a reduced operational capacity of the Family Health Strategy (FHS) regarding leprosy control actions and the need to implement the policy according to the Unified Health System (SUS, from its acronym in Portuguese).

show abstract

“…Difficulty in carrying out day-to-day tasks which require preserved neural function leads the patients themselves to evaluate their health as impaired. 10 Access to rehabilitation services still functions in a one-way direction, i.e., patient-service, which does not favour accessibility to those most in need. Individuals with disabilities need treatment centres close to where they live if the care and guidance of the professionals is to be effective.…”

Section: Discussionmentioning

confidence: 99%

Deficiências após a alta medicamentosa da hanseníase: prevalência e distribuição espacial

et al. 2012

View full text Add to dashboard Cite

OBJECTIVE:To estimate the frequency of people with leprosy-related physical disabilities after release from multidrug treatment and to analyze their spatial distribution. METHODS:Descriptive cross-sectional study with 232 leprosy patients treated between 1998 and 2006. Physical disabilities were assessed using the World Health Organization disability grading and the eye-hand-foot (EHF) sum score. The residential address of patients and rehabilitation centers were geocoded. It was estimated the overall frequency of physical disability and frequency by disability grade (grade 0, grade 1, and grade 2) according to the WHO disability grading taking into consideration clinical and sociodemographic variables in the descriptive analysis. Student's t-test, chi-square test (χ2), and Fisher's test were used as appropriate at a 5% signifi cance level. RESULTS:Of the patients studied, 51.6% were female, mean age 54 years old (SD 15.7), 30.5% had less than 2 years of formal education, 43.5% were employed, and 26.9% were retired. Borderline leprosy was the most prevalent form of leprosy (39.9%). A total of 32% of these patients had disabilities according to the WHO disability grading and the EHF score. Disabilities increased with age (p = 0.029), they were more common in patients with multibacillary leprosy (p = 0.005) and poor self-rated physical health (p < 0.001). Those who required prevention/rehabilitation care traveled on average 5.5 km to the rehabilitation center. People with physical disabilities lived scattered across the city but they were mostly concentrated in the most densely populated and socioeconomically deprived area. CONCLUSIONS:There is a high frequency of people with leprosy-related disabilities after release from multidrug therapy. Prevention and rehabilitation actions should target uneducated and older patients, those who had multibacillary forms of leprosy and poor self-rated physical health. The travel distance to rehabilitation centers calls for reorganization of local care networks.

show abstract

The impact of leprosy on health-related quality of life

Cited by 82 publications

References 15 publications

Analysis of clinical data and T helper 1/T helper 2 responses in patients with different clinical forms of leprosy

Analysis of clinical data and T helper 1/T helper 2 responses in patients with different clinical forms of leprosy

Incapacidades Físicas Em Hanseníase: Caracterização, Fatores Relacionados E Evolução

Deficiências após a alta medicamentosa da hanseníase: prevalência e distribuição espacial

Contact Info

Product

Resources

About