The Impact of COVID-19 on Dermatology Clinical Trials

Desai, Sheena; Manjaly, Priya; Lee, Karen J.; Li, Sara J.; Manjaly, Cyriac; Mostaghimi, Arash

doi:10.1016/j.jid.2020.06.032

Cited by 13 publications

(7 citation statements)

References 4 publications

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“…It has been reported that the pandemic has mainly affected the conduct of clinical trials unrelated to the COVID-19 disease [2,5,12,13]. Earlier studies have documented a slowdown in completing trials [9,14] and even suspension of non-COVID-19 clinical trials [15,16], during this pandemic period. Mitchell et al have reported that some studies which have continued have seen a significant reduction in their recruitment numbers [2].…”

Section: Discussionmentioning

confidence: 99%

Impact of coronavirus disease-19 pandemic on pediatric vaccine clinical trials

Hanumante¹,

Desale²

2021

Indian J Child Health

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T he World Health Organization declared coronavirus disease (COVID)-19 a public health emergency of international concern on January 30, 2020, and later declared a pandemic on March 11, 2020 [1]. The first confirmed case of coronavirus in Maharashtra was reported on March 9, 2020, in our city of Pune. Gradually, the pandemic spreads to all parts of the country, and eventually, the tally of COVID-19 cases by December 2020 touched 10 million.The COVID-19 pandemic has affected nearly every facet of life, including clinical research and has had an adverse and extensive impact on clinical trials including pediatric vaccine trials. Across the globe, countries implemented a variety of restrictions to people's everyday lives which included, countrywide lockdowns, and social distancing, which have been major detrimental factors for the conduct of pediatric vaccine trials [2]. The present study was proposed to assess the impact of the COVID-19 pandemic on enrollment and follow-up of clinical trial participants in pediatric vaccine clinical trials and simultaneously to explore various strategies used for overcoming these challenges during the COVID-19 pandemic. MATERIALS AND METHODSThis observational, cross-sectional study was conducted in the Clinical Research Unit of a tertiary care multispecialty hospital in Pune, where pediatric vaccine clinical trials are routinely

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Section: Discussionmentioning

confidence: 99%

Impact of coronavirus disease-19 pandemic on pediatric vaccine clinical trials

Hanumante¹,

Desale²

2021

Indian J Child Health

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“…Clinical research suffered a dramatic decline in participation during the COVID-19 pandemic [ 1 ]. Desai et al reported that 57 dermatology-related clinical trials during March, April, and May of 2020 were suspended, withdrawn, or terminated, affecting an estimated 7141 patients [ 2 ]. In addition to the many research patients affected during the pandemic, progress across many studies was impeded, potentially leading to delays in drug development.…”

Section: Lessons Learned From the Impact Of Covid-19 On Dermatology Clinical Researchmentioning

confidence: 99%

Perspectives on the Future Development of Mobile Applications for Dermatology Clinical Research

Hadeler

Hong

Mosca

et al. 2021

Dermatol Ther (Heidelb)

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The COVID-19 pandemic significantly impacted clinical research in dermatology and practices around the country transitioned to teledermatology amid physical distancing requirements. Despite their growing use in teledermatology and clinical care, dermatology applications have not been studied extensively in the research space. The use of mobile applications has the potential to improve the experience of study subjects and physicians and increase the pool of individuals willing to participate in research beyond the pandemic. We discuss the various pros and cons of mobile apps, as well as the necessary components they require to successfully conduct research.

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“…Since the onset of the pandemic in the United States in March, at least 440 clinical trials were suspended or delayed 2 . Specifically, an increase in suspension, withdrawal, and termination of clinical trials for dermatologic conditions has been observed during the initial months of the COVID‐19 pandemic 3 . There have also been changes in the peer review process, with some journals accelerating their peer review process for papers focused on COVID‐19 4 .…”

Section: Figurementioning

confidence: 99%

“…increase in suspension, withdrawal, and termination of clinical trials for dermatologic conditions has been observed during the initial months of the COVID-19 pandemic. 3 There have also been changes in the peer review process, with some journals accelerating their peer review process for papers focused on COVID-19. 4 The goal of this study was to systematically review publications to identify the impact of COVID-19 on the publication rate of clinical trials in dermatology.…”

mentioning

confidence: 99%