The Immune System in IBD: Antimicrobial Peptides

Bevins, Charles L.

doi:10.1007/978-3-319-33703-6_5

Cited by 2 publications

(3 citation statements)

References 175 publications

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“… 3 Alterations in gut microbiota in IBD may include qualitative and quantitative modifications of its composition and changes in microbial functional activity. 3 , 4 …”

Section: Introductionmentioning

confidence: 99%

“…In the gastrointestinal tract HDPs protect the host against pathogens overgrowth and invasion, and on the other hand modulate the composition of the endogenous microbiota, contributing to the gut homeostasis. 4 , 9 Thus, altered expression and impaired activity of HDPs may play an important role in IBD pathogenesis. 2 , 4 , 10 …”

Section: Introductionmentioning

confidence: 99%

“… 4 , 9 Thus, altered expression and impaired activity of HDPs may play an important role in IBD pathogenesis. 2 , 4 , 10 …”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Cathelicidin – A Novel Potential Marker of Pediatric Inflammatory Bowel Disease

Krawiec

Pac-Kożuchowska

2021

JIR

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“… 3 Alterations in gut microbiota in IBD may include qualitative and quantitative modifications of its composition and changes in microbial functional activity. 3 , 4 …”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Cathelicidin – A Novel Potential Marker of Pediatric Inflammatory Bowel Disease

Krawiec

Pac-Kożuchowska

2021

JIR

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The Gut Microbiome and Inflammatory Bowel Diseases

2022

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Inflammatory bowel diseases (IBD) arise from a convergence of genetic risk, environmental factors, and gut microbiota, where each is necessary but not sufficient to cause disease. Emerging evidence supports a bidirectional relationship between disease progression and changes in microbiota membership and function. Thus, the study of the gut microbiome and host–microbe interactions should provide critical insights into disease pathogenesis as well as leads for developing microbiome-based diagnostics and interventions for IBD. In this article, we review the most recent advances in understanding the relationship between the gut microbiota and IBD and highlight the importance of going beyond establishing description and association to gain mechanistic insights into causes and consequences of IBD. The review aims to contextualize recent findings to form conceptional frameworks for understanding the etiopathogenesis of IBD and for the future development of microbiome-based diagnostics and interventions. Expected final online publication date for the Annual Review of Medicine, Volume 73 is January 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

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The Immune System in IBD: Antimicrobial Peptides

Cited by 2 publications

References 175 publications

Cathelicidin – A Novel Potential Marker of Pediatric Inflammatory Bowel Disease

Cathelicidin – A Novel Potential Marker of Pediatric Inflammatory Bowel Disease

The Gut Microbiome and Inflammatory Bowel Diseases

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