The human papillomaviruses. A review

Lutzner, Marvin A.

doi:10.1001/archderm.119.8.631

Cited by 17 publications

(14 citation statements)

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“…While the two monoclonals detected HPV-1 antigens in frozen sections of plantar warts at a 1/400 dilution, no reaction was observed at a 1/10 dilution using frozen sections of warts induced by HPV types 2, 3, 4, 5 or 7 (Lutzner, 1983), neither by the immunofluorescence nor the immuno- Fig. 1.…”

Section: Resultsmentioning

confidence: 83%

“…The specific association of some HPV types with cutaneous and genital cancers has recently been substantiated (D~irst et aL, 1983;Lutzner, 1983;Orth et al, 1980;zur Hausen, 1981). The study of the antigenic properties of the PVs, as well as that of the structural polypeptides of the virions, have been hampered by the unavailability of a system allowing replication in vitro of these viruses (Lancaster & Olson, 1982;Lutzner, 1983;zur Hausen, 1981). Type-specific antigens have been demonstrated by the lack of detectable antigenic cross-reactions between some animal and human PVs and between some skin HPVs Le Bouvier et al, 1966;Orth et al, 1977Orth et al, , 1980, using hyperimmune sera against intact viral particles.…”

Section: Introductionmentioning

confidence: 96%

“…(Favre et al, 1975aGissmann et al, 1977;Lancaster & Olson, 1982;Meinke & Meinke, 1981 ;Orth et al, 1977Orth et al, , 1978Pass & Maizel, 1973 ;Pfister et al, 1977). In man, papillomaviruses (PVs) induce benign epithelial tumours of the skin and mucous membranes (warts, condylomas), which may evolve into carcinomas in some instances (Lutzner, 1983;Orth et aL, 1980;zur Hausen, 1981). Sixteen types of human papillomaviruses (HPVs) have been identified so far, the basis of classification being a DNA sequence homology on cross-hybridization lower than 50 (Dfirst et al, 1983;Lutzner, 1983).…”

Section: Introductionmentioning

confidence: 99%

“…In man, papillomaviruses (PVs) induce benign epithelial tumours of the skin and mucous membranes (warts, condylomas), which may evolve into carcinomas in some instances (Lutzner, 1983;Orth et aL, 1980;zur Hausen, 1981). Sixteen types of human papillomaviruses (HPVs) have been identified so far, the basis of classification being a DNA sequence homology on cross-hybridization lower than 50 (Dfirst et al, 1983;Lutzner, 1983). The specific association of some HPV types with cutaneous and genital cancers has recently been substantiated (D~irst et aL, 1983;Lutzner, 1983;Orth et al, 1980;zur Hausen, 1981).…”

Section: Introductionmentioning

confidence: 99%

“…Sixteen types of human papillomaviruses (HPVs) have been identified so far, the basis of classification being a DNA sequence homology on cross-hybridization lower than 50 (Dfirst et al, 1983;Lutzner, 1983). The specific association of some HPV types with cutaneous and genital cancers has recently been substantiated (D~irst et aL, 1983;Lutzner, 1983;Orth et al, 1980;zur Hausen, 1981). The study of the antigenic properties of the PVs, as well as that of the structural polypeptides of the virions, have been hampered by the unavailability of a system allowing replication in vitro of these viruses (Lancaster & Olson, 1982;Lutzner, 1983;zur Hausen, 1981).…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Monoclonal Antibodies to the Major Capsid Protein of Human Papillomavirus Type 1

Roseto

Pothier

Guillemin

et al. 1984

Journal of General Virology

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Section: Resultsmentioning

confidence: 83%

Section: Introductionmentioning

confidence: 96%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Monoclonal Antibodies to the Major Capsid Protein of Human Papillomavirus Type 1

Roseto

Pothier

Guillemin

et al. 1984

Journal of General Virology

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Verrucous Cyst

Meyer¹

1991

Arch Dermatol

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Human papillomavirus has been detected in a variety of cutaneous premalignant and malignant conditions, as well as in benign cutaneous warts. Changes consistent with epidermis papilloma virus infection occurring in epidermal cysts have recently been reported in the dermatologic literature only in plantar epidermal cysts. We report five examples of a form of cutaneous cyst that is histologically distinctive and that has not been previously reported, to our knowledge. We describe five cases of epidermal cysts showing marked verrucous changes of their stratified squamous inner linings, some of which also show proliferative changes. Human papillomavirus genomes were detected via polymerase chain reaction. None of the DNA probes for Southern blot hybridization demonstrated homology with the human papillomavirus types usually associated with cutaneous warts or carcinoma. We believe this cyst to represent a newly described manifestation of human papillomavirus infection, and propose the name verrucous cyst for this entity. Further studies may reveal the specific human papillomavirus type(s) associated with the verrucous cyst.

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Detection of several types of human papilloma viruses in AIDS‐associated Kaposi's sarcoma

Adams

Kempf

Hassam

et al. 1995

Journal of Medical Virology

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Epidemiological studies indicate that acquired immunodeficiency syndrome (AIDS)-associated Kaposi's sarcoma (KS) may be caused by an infectious, preferentially sexually transmitted agent. Infections with human papilloma viruses are common, sexually transmitted diseases occurring frequently in homosexual men, who are also the main risk group for developing KS. In order to evaluate the possible role of HPV in the development of KS, 24 cutaneous AIDS-associated Kaposi's sarcomas were investigated by the polymerase chain reaction (PCR) and by in situ hybridization for the presence of human papilloma viruses (HPV). HPV DNA sequences were detected in 5 of 24 KS specimens, in 4 of 13 normal skin specimens from AIDS patients without KS and in 5 of 14 skin specimens of HIV-seronegative patients. For the first time, HPV types 6 and 33 were detected by PCR in KS. A higher proportion of HPV types 16/18 was found in AIDS-associated KS specimens, whereas HPV type 33 was seen more often in normal skin specimens of the control group. Apart from the known HPV types 16/18 described in KS, this study demonstrates also the presence of HPV 6 and 33 in this condition.

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The human papillomaviruses. A review

Cited by 17 publications

References 0 publications

Monoclonal Antibodies to the Major Capsid Protein of Human Papillomavirus Type 1

Monoclonal Antibodies to the Major Capsid Protein of Human Papillomavirus Type 1

Verrucous Cyst

Detection of several types of human papilloma viruses in AIDS‐associated Kaposi's sarcoma

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