The grafting of acrylamide onto poly(?-caprolactone) and poly(1,5-dioxepan-2-one) using electron beam preirradiation. II. Anin vitro degradation study on grafted poly(?-caprolactone)

Electron Beam-Induced Graft Polymerization of Acrylic Acid and Immobilization of Arginine−Glycine−Aspartic Acid-Containing Peptide onto Nanopatterned Polycaprolactone

“…Our earlier experiments showed that the degree of grafting is highly dosedependent. 18 Since we aim to produce model surfaces for studies of the cell response to both surface topography and surface chemistry, it was important that the surface topography after grafting and peptide coupling should not be significantly altered; that is, the parallel grooves should not be fully filled with AAc grafts. For this reason, a relatively low preirradiation dose of 1 Mrad was used.…”

“…The subsequent exposure of this preirradiated surface to an acrylic acid solution in the presence of Mohr's salt led to a graft polymerization of acrylic acid onto the polymer substrate. Our earlier experiments showed that the degree of grafting is highly dose-dependent . Since we aim to produce model surfaces for studies of the cell response to both surface topography and surface chemistry, it was important that the surface topography after grafting and peptide coupling should not be significantly altered; that is, the parallel grooves should not be fully filled with AAc grafts.…”

Recent Developments in Ring Opening Polymerization of Lactones for Biomedical Applications

“…Acrylamide could be successfully grafted onto cross-linked PDXO by electron-beam irradiation. , Other researchers − have also used a similar two step procedure involving preparation of a linear prepolymer followed by cross-linking reaction.…”

Hydrogel‐Reactive‐Microenvironment Powering Reconfiguration of Polymer Architectures

“…[43] Our experimental results agree with those of Albertsson's group, who found that a PCL film preirradiated by electron beams could be graft-polymerized with AAm as a monomer in an aqueous solution, resulting in volumetric expansion of PCL film. [51,52] The researchers further built a multi-layer model of water diffusion in AAm-grafted aliphatic polyesters, including PCL. [53] The static water contact angles of the pure PCL lattice and the PCL-PAAm lattice were 124°and 44°, respectively (Figure 2i).…”