The Global Pertussis Initiative: Meeting report from the fourth regional roundtable meeting, France, April 14-15, 2010

Guiso, Nicole; Liese, Johannes G.; Plotkin, Stanley А.

doi:10.4161/hv.7.4.14528

Cited by 45 publications

(33 citation statements)

References 15 publications

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“…In locations with low vaccination coverage, circulation of B. pertussis in the community accounts for natural "boost". However, vaccination leads to a reduction in bacterial circulation and a subsequent loss of protection after natural infection, resulting in an increase in the incidence of the disease among teenagers and young adults, who become an significant source of infection of children 29,30,31,32,33,34,35,36,37,38,39,40 .…”

Section: Pertussis Vaccinesmentioning

confidence: 99%

“…Adults generally develop a milder form of the disease than children, however morbidity and the chances of complications are high 1,7,21,22,23,24,29,30 . In adults the disease generally lasts for four weeks, with 25% of patients developing complications 24 .…”

Section: Pertussis In Hcps: Risks To Patients and Health Workersmentioning

confidence: 99%

“…During the last decade, the use of these vaccines for adolescents and adults, particularly those in contact with young babies, has been introduced in several countries 3,6,7,18,19,25,26,27,29,30,31,32,38,43,46,49,52,57 .…”

Section: Pertussis Vaccinesmentioning

confidence: 99%

“…The inclusion of the acellular pertussis vaccine is due to an increase in the incidence of pertussis in certain European countries 28,29,30,31,32,33,34,35,36,37,38,39,40 , the USA 1,78,9,10,11,12,21,24,25,26,27 , Canada 13,22,23 and Australia 16,17,41,42,43 . In these regions pertussis currently affects all age groups, and incidence rates are particularly high in adolescents and young adults 36,38,43 .…”

Section: Vaccine Recommendations For Hcpsmentioning

confidence: 99%

“…However, HCP vaccination policies vary considerably between different countries 3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19 and have changed over the two last decades due to new information on the epidemiological profile of pertussis and licensing of new safe and effective vaccines for use in adolescents and adults, such as the triple acellular (Tdap) vaccine that, besides protecting against diphtheria and tetanus, also protects against pertussis, and the quadruple vaccine against diphtheria, tetanus and pertussis combined with the inactivated polio vaccine (Tdap-IPV), already licensed in a number of countries 7,8,9,10,11,12,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,…”

Section: Introductionmentioning

confidence: 99%

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Should acellular pertussis vaccine be recommended to healthcare professionals?

Moraes¹,

Carvalhanas

Bricks³

2013

Cad. Saúde Pública

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The aim of this study was to describe recent changes in the epidemiology of pertussis and existing policies regarding recommended and mandatory occupational vaccinations for healthcare professionals (HCPs). The authors carried out an extensive review of references on the PubMed and SciELO databases and the official sites of the World Health Organization, Pan American Health Organization, Centers for Disease Control and Prevention, and Brazilian Ministry of Health, using the keywords pertussis, vaccines and healthcare professionals. Vaccination against pertussis is recommended for HCPs in the United States, Canada, nine European countries, Australia, Hong Kong, Singapore, Costa Rica, Argentina and Uruguay, and in some countries it is compulsory. In Brazil, only one publication discussing the risk of pertussis among HCPs was found. Considering the reemergence of pertussis and the great number of associated hospitalizations and deaths registered in 2011, it is necessary to review public policies regarding HCP pertussis vaccination, particularly among workers in frequent contact with young babies.

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Section: Pertussis Vaccinesmentioning

confidence: 99%

Section: Pertussis In Hcps: Risks To Patients and Health Workersmentioning

confidence: 99%

Section: Pertussis Vaccinesmentioning

confidence: 99%

Section: Vaccine Recommendations For Hcpsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Should acellular pertussis vaccine be recommended to healthcare professionals?

Moraes¹,

Carvalhanas

Bricks³

2013

Cad. Saúde Pública

View full text Add to dashboard Cite

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Hospitalizations for pertussis in Italy, 1999–2009: analysis of the hospital discharge database

Gabutti¹,

Rota

Bonato

et al. 2012

Eur J Pediatr

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Even if the incidence of pertussis has greatly decreased after the adoption of immunization, it still remains a relevant cause of death in infants in their first years of life. At national level, data are usually greatly underestimated. The objective of this study was to retrospectively review the national hospital discharge form database. The national database was retrospectively searched using the International Classification of Diseases, ninth revision, Clinical Modification system. In the period 1999-2009, 7,768 hospitalizations for pertussis (primary diagnosis) have been registered: 6,971 hospitalizations and 797 day hospital admissions. The annual mean was equal to 633.6 hospitalizations and 72.4 day hospital admissions. The majority of hospitalizations (57.4 %) involved subjects <1 year of age; the mean duration of stay was about 6 days. Conclusion These data, even if restricted to hospitalizations registered at national level, confirm the epidemiological impact of pertussis and its complications in a country with a consistently high vaccination coverage rate.

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Childhood infectious disease and premature death from cancer: a prospective cohort study

et al. 2013

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Studies of the association between early life infections and cancer have produced inconsistent findings, possibly due to limited adjustment for confounding and retrospective designs. This study utilised data from the Newcastle Thousand Families Study, a prospective cohort of 1,142 individuals born in Newcastle-upon-Tyne in 1947, to assess the impact of various childhood infectious diseases on cancer mortality during ages 15-60 years. Detailed information was collected prospectively on a number of early life factors. Deaths from cancer during ages 15-60 years were analysed in relation to childhood infections, adjusting for potential early-life confounders, using Cox proportional-hazards regression. In a subsample who returned questionnaires at aged 49-51 years, additional adjustment was made for adult factors to predict death from cancer during ages 50-60 years. Childhood history of measles and influenza, were both independently associated with lower cancer mortality during ages 15-60 years (adjusted hazard ratios = 0.39, 95% CI 0.17-0.88 and 0.49, 95% CI 0.24-0.98 respectively). In contrast, childhood pertussis was associated with higher cancer mortality during ages 15-60 years (adjusted hazard ratio = 4.88, 95% CI 2.29-10.38). In the subsample with additional adjustment for adult variables, measles and pertussis remained significantly associated with cancer mortality during ages 50-60 years. In this pre-vaccination cohort, childhood infection with measles and influenza were associated with a reduced risk of death from cancer in adulthood, while pertussis was associated with an increased risk. While these results suggest some disease-specific associations between early-life infections and cancer, further studies are required to confirm the specific associations identified.

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The Global Pertussis Initiative: Meeting report from the fourth regional roundtable meeting, France, April 14-15, 2010

Cited by 45 publications

References 15 publications

Should acellular pertussis vaccine be recommended to healthcare professionals?

Should acellular pertussis vaccine be recommended to healthcare professionals?

Hospitalizations for pertussis in Italy, 1999–2009: analysis of the hospital discharge database

Childhood infectious disease and premature death from cancer: a prospective cohort study

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