1972
The genetics of psoriasis
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1972
2025
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Cited by 48 publications
(8 citation statements)
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“…When the sexes are not considered separately and estimations are made on a io-year basis, the peak age-of-onset is seen to be between 10 and 20 years, which accords with the findings of Church (1958), Farber & Carlsen (1966 and Watson et al (1972). Similarly, the age-of-onset was before the age of 20 in 37% of the patients and before the age of 30 years in 57% .…”
Section: Discussion
supporting
confidence: 88%
“…When the sexes are not considered separately and estimations are made on a io-year basis, the peak age-of-onset is seen to be between 10 and 20 years, which accords with the findings of Church (1958), Farber & Carlsen (1966 and Watson et al (1972). Similarly, the age-of-onset was before the age of 20 in 37% of the patients and before the age of 30 years in 57% .…”
Section: Discussion
supporting
confidence: 88%
“…In the first group the incidence of psoriasis in a parent of a proband is 22-5% almost identical with the 23% observed by Lomholt. For the second group of patients this incidence is 14-6%, which is very close to the 14% observed by Watson et al (1972) in their retrospective survey.…”
Section: Discussion
supporting
confidence: 78%
“…Genetics have been linked to psoriasis for 50 years [26]. Genetic analysis has enabled the detection and analysis of more susceptibility genes as predictive markers of therapy response when unexplained and unsatisfactory treatment responses and side effects are reported [27].…”
Section: Discussion
mentioning
confidence: 99%
“…Incidentally, both the PRL gene and the human leucocyte antigen (HLA) complex are present on chromosome 6 and some of the antigens of the HLA complex, particularly Cw6 and DR7, are implicated in the aetiopathogenesis of psoriasis as a probable explanation for genetic predisposition to the disease [1, 2, 24, 25]. Is it a coincidence or is there a genetic relationship between PRL gene and HLA complex?…”
Section: Discussion
mentioning
confidence: 99%
