1972
DOI: 10.1001/archderm.105.2.197
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The genetics of psoriasis

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Cited by 48 publications

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“…When the sexes are not considered separately and estimations are made on a io-year basis, the peak age-of-onset is seen to be between 10 and 20 years, which accords with the findings of Church (1958), Farber & Carlsen (1966 and Watson et al (1972). Similarly, the age-of-onset was before the age of 20 in 37% of the patients and before the age of 30 years in 57% .…”
Section: Discussion
supporting
confidence: 88%
“…In the first group the incidence of psoriasis in a parent of a proband is 22-5% almost identical with the 23% observed by Lomholt. For the second group of patients this incidence is 14-6%, which is very close to the 14% observed by Watson et al (1972) in their retrospective survey.…”
Section: Discussion
supporting
confidence: 78%
See 1 more Smart Citation
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…When the sexes are not considered separately and estimations are made on a io-year basis, the peak age-of-onset is seen to be between 10 and 20 years, which accords with the findings of Church (1958), Farber & Carlsen (1966 and Watson et al (1972). Similarly, the age-of-onset was before the age of 20 in 37% of the patients and before the age of 30 years in 57% .…”
Section: Discussion
supporting
confidence: 88%
“…In the first group the incidence of psoriasis in a parent of a proband is 22-5% almost identical with the 23% observed by Lomholt. For the second group of patients this incidence is 14-6%, which is very close to the 14% observed by Watson et al (1972) in their retrospective survey.…”
Section: Discussion
supporting
confidence: 78%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Genetics have been linked to psoriasis for 50 years [26]. Genetic analysis has enabled the detection and analysis of more susceptibility genes as predictive markers of therapy response when unexplained and unsatisfactory treatment responses and side effects are reported [27].…”
Section: Discussion
mentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Incidentally, both the PRL gene and the human leucocyte antigen (HLA) complex are present on chromosome 6 and some of the antigens of the HLA complex, particularly Cw6 and DR7, are implicated in the aetiopathogenesis of psoriasis as a probable explanation for genetic predisposition to the disease [1, 2, 24, 25]. Is it a coincidence or is there a genetic relationship between PRL gene and HLA complex?…”
Section: Discussion
mentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.