The formation principle of micro-droplets induced by using optical tweezers

Zhai, Cong; Hu, Chunguang; Li, Shuai; Ma, Yuanyuan; Guo, Tong; Li, Hongbin; Hu, Xiaotang

doi:10.1039/d0na00705f

Cited by 7 publications

(3 citation statements)

References 39 publications

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“…DMF could manipulate nanoliter to microliter droplets on a plain surface. Depending on the actuation mechanism used, DMF can be classified into various categories, including electrowetting on dielectric [ 73 – 75 ], magnetic [ 76 – 78 ], surface acoustic wave [ 79 , 80 ], and other types [ 81 , 82 ]. Despite the widespread popularity of the electrowetting-on-dielectric actuation method, the magnetic actuation approach continues to offer important and irreplaceable benefits, as noted by Zhang and Nguyen [ 83 ].…”

Section: Magnetic Bead Manipulation In Microfluidic Chipmentioning

confidence: 99%

Magnetic Bead Manipulation in Microfluidic Chips for Biological Application

et al. 2023

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Magnetic beads manipulation in microfluidic chips is a promising research field for biological application, especially in the detection of biological targets. In this review, we intend to present a thorough and in-depth overview of recent magnetic beads manipulation in microfluidic chips and its biological application. First, we introduce the mechanism of magnetic manipulation in microfluidic chip, including force analysis, particle properties, and surface modification. Then, we compare some existing methods of magnetic manipulation in microfluidic chip and list their biological application. Besides, the suggestions and outlook for future developments in the magnetic manipulation system are also discussed and summarized.

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Section: Magnetic Bead Manipulation In Microfluidic Chipmentioning

confidence: 99%

Magnetic Bead Manipulation in Microfluidic Chips for Biological Application

et al. 2023

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“…Soft matter, including liquid crystals (LC), colloids, polymers, and biological substances, exhibits widespread influence across nature, living organisms, daily life, and industry [ 2 , 5 , 6 ]. The biomimetic properties, responsiveness to stimuli, and efficacy in controlled release and sensing make soft matter extensively applicable in biology and chemistry [ 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 ]. Additionally, soft matter offers distinct advantages over solids in optical and photonic applications owing to its inherent adaptability, tunability, and seamless integration capabilities [ 3 , 20 , 21 , 22 , 23 , 24 , 25 ].…”

Section: Introductionmentioning

confidence: 99%

Recent Progress in Droplet Structure Machining for Advanced Optics

Guo,

Sandaruwan,

et al. 2024

Micromachines

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The development of optical and photonic applications using soft-matter droplets holds great scientific and application importance. The machining of droplet structures is expected to drive breakthroughs in advancing frontier applications. This review highlights recent advancements in micro–nanofabrication techniques for soft-matter droplets, encompassing microfluidics, laser injection, and microfluidic 3D printing. The principles, advantages, and weaknesses of these technologies are thoroughly discussed. The review introduces the utilization of a phase separation strategy in microfluidics to assemble complex emulsion droplets and control droplet geometries by adjusting interfacial tension. Additionally, laser injection can take full advantage of the self-assembly properties of soft matter to control the spontaneous organization of internal substructures within droplets, thus providing the possibility of high-precision customized assembly of droplets. Microfluidic 3D printing demonstrates a 3D printing-based method for machining droplet structures. Its programmable nature holds promise for developing device-level applications utilizing droplet arrays. Finally, the review presents novel applications of soft-matter droplets in optics and photonics. The integration of processing concepts from microfluidics, laser micro–nano-machining, and 3D printing into droplet processing, combined with the self-assembly properties of soft materials, may offer novel opportunities for processing and application development.

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“…Microfluidics is now able to perform a range of functions in the fields of chemical analysis 2,3 and biological detection, [4][5][6][7][8] such as organismal body analysis, 9 drug encapsulation, 10 cell encapsulation, 11 cell screening and sequencing, 12 and nebulizer treatment, 13 etc. Among these examples, microfluidics has demonstrated the ability to manipulate individual droplets and micro to nano-objects in liquids, enabled by various forces associated with magnetics, 14 optical, 15 acoustics, 16,17 electrowetting-ondielectrics, dielectrophoresis, and hydrodynamics. Acoustic tweezers based on bulk acoustic waves (BAWs) 18 and surface acoustic waves (SAWs) 19,20 allow for on-chip micromanipulation that is contactless, 21 non-invasive, 22 and highly biocompatible.…”

Section: Introductionmentioning

confidence: 99%