The first year on haemodialysis: a critical transition

Broers, Natascha J. H.; Cuijpers, Anne C M; Sande, Frank M. van der; Leunissen, Karel M.L.; Kooman, Jeroen P.

doi:10.1093/ckj/sfv021

Cited by 35 publications

(47 citation statements)

References 95 publications

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“…1,2 Maintaining data continuity through the transition from pre-dialysis to post-dialysis start is complex since clinical data which spans predialysis nephrology practice care to post-dialysis start is usually not contained in a single database. 1,2 Maintaining data continuity through the transition from pre-dialysis to post-dialysis start is complex since clinical data which spans predialysis nephrology practice care to post-dialysis start is usually not contained in a single database.…”

Section: Introductionmentioning

confidence: 99%

Clinical parameters before and after the transition to dialysis

Maddux

Usvyat

Ketchersid

et al. 2017

Hemodialysis International

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This study uniquely demonstrates the trajectories of key parameters though the transition from pre-dialysis to post-dialysis start. Significant differences are noted in the pre-dialysis period for patients who survive vs. those who do not survive the first year of dialysis. Early recognition of adverse trends in the pre-dialysis period may create opportunity to intervene to improve early dialysis outcomes.

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Section: Introductionmentioning

confidence: 99%

Clinical parameters before and after the transition to dialysis

Maddux

Usvyat

Ketchersid

et al. 2017

Hemodialysis International

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“…In contrast, the current framework has been developed from research exploring patients' experiences of dialysis dependence; as such, it provides an opportunity to consider research and clinical outcomes that are likely to be of importance to patients. Although dialysis-requiring ESRD is recognized to be associated with increased mortality and changes in other clinical parameters, relatively less attention has been paid to the psychosocial effects of starting dialysis (42)(43)(44). The need for additional research into the psychosocial effects of CKD was also highlighted in a study of patients' priorities for health research (9).…”

Section: Discussionmentioning

confidence: 99%

A Thematic Synthesis of the Experiences of Adults Living with Hemodialysis

Reid

Seymour

Jones

2016

CJASN

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Background and objectives Patients on in-center dialysis spend significant amounts of time in the dialysis unit; additionally, managing ESRD affects many aspects of life outside the dialysis unit. To improve the care provided to patients requiring hemodialysis, their experiences and beliefs regarding treatment must be understood. This systematic review aimed to synthesize the experiences of patients receiving in-center hemodialysis.Design, setting, participants, & measurements We searched Embase, MEDLINE, CINAHL, PsychINFO, Google Scholar, and reference lists for primary qualitative studies published from 1995 to 2015 that explored the experiences of adult patients receiving treatment with in-center hemodialysis. A thematic synthesis was conducted.Results Seventeen studies involving 576 patients were included in the synthesis. Four analytic themes were developed. The first theme (a new dialysis-dependent self) describes the changes in identity and perceptions of self that could result from dialysis dependence. The second theme (a restricted life) describes the physical and emotional constraints that patients described as a consequence of their dependence. Some patients reported strategies that allowed them to regain a sense of optimism and influence over the future, and these contributed to the third theme (regaining control). The first three themes describe a potential for change through acceptance, adaption, and regaining a sense of control. The final theme (relationships with health professionals) describes the importance of these relationships for in-center patients and their influence on perceptions of power and support. These relationships are seen to influence the other three themes through information sharing, continuity, and personalized support.Conclusions Our synthesis has resulted in a framework that can be used to consider interventions to improve patients' experiences of in-center hemodialysis care. Focusing on interventions that are incorporated into the established relationships that patients have with their health care professionals may enable patients to progress toward a sense of control and improve satisfaction with care.

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“…Predictor variables and multivariate model of all-cause mortality in dialysis patients are multifactorial. The progressive loss of renal function and dialysis itself may contribute to the progression of CVD [20].…”

Section: Discussionmentioning

confidence: 99%

Mortality and Associated Risk Factors in Dialysis Patients with Cardiovascular Disease

Tong

Liu

Li³

et al. 2016

Kidney Blood Press Res

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Background/Aims: Although dialysis patients have a higher risk of morbidity and mortality related to cardiovascular disease (CVD) than the general population, the mortality and associated risk factors in Asian dialysis patients with CVD have not been well examined. Methods: In this prospective cohort study, mortality and risk factors were investigated in 591 dialysis patients who were recruited from two dialysis centers from May 1, 2009 to May 1, 2014. The Cox proportional hazards regression assessed adjusted differences in mortality risk. A multivariate analysis was also performed, comparing the CVD and non-CVD groups. Results: A total of 591 patients were enrolled in this study (mean age, 52.05 ± 16.46 years [SD]; 61.8% men; 20.8% with CVD), with a median follow-up of 21.9 (maximum, 72) months. The cumulative hazard of mortality was significantly higher in CVD patients (hazard ratio [HR], 1.835; 95% confidence interval [CI], 1.023-3.293; P=0.042) than in their non-CVD counterparts after adjusting for various confounders. On multivariate Cox analysis, stroke (HR, 4.574; 95% CI, 2.149-9.736; P<0.001) was an independent predictor of all-cause mortality in the CVD group. In the non-CVD group, diabetes mellitus (HR, 2.974; 95% CI, 1.560-5.668; P=0.001) and elevated high-sensitivity C-reactive lipoprotein (hs-CRP) (HR, 1.017; 95% CI, 1.005-1.030; P=0.005) were independent predictors of all-cause mortality. Conclusion: All-cause mortality was significantly higher in the CVD group than in the non-CVD group. Stroke is an independent risk factor for all-cause mortality in dialysis patients with CVD. These findings warrant further studies into preventive and interventional strategies.

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The first year on haemodialysis: a critical transition

Cited by 35 publications

References 95 publications

Clinical parameters before and after the transition to dialysis

Clinical parameters before and after the transition to dialysis

A Thematic Synthesis of the Experiences of Adults Living with Hemodialysis

Mortality and Associated Risk Factors in Dialysis Patients with Cardiovascular Disease

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