The expression of Catsup in escort cells affects Drosophila ovarian stem cell niche establishment and germline stem cells self-renewal via Notch signaling

Gao, Jiajia; Xiao, Guiran

doi:10.1016/j.bbrc.2022.11.101

Cited by 1 publication

(1 citation statement)

References 41 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…At the germarium’s anterior tip, the terminal filament cells and cap cells form the niche that sustains two to three ovarian GSCs. Proper Notch signaling is critical for the development of both terminal filament cells and cap cells [ 244 , 245 , 246 , 247 , 248 , 249 , 250 , 251 , 252 , 253 ]. The strength of Notch signaling also dictates the size of the ovarian GSC niche.…”

Section: Notch Signaling In Insect Reproductionmentioning

confidence: 99%

Notch Signaling in Insect Development: A Simple Pathway with Diverse Functions

Chen,

Li,

et al. 2023

IJMS

View full text Add to dashboard Cite

Notch signaling is an evolutionarily conserved pathway which functions between adjacent cells to establish their distinct identities. Despite operating in a simple mechanism, Notch signaling plays remarkably diverse roles in development to regulate cell fate determination, organ growth and tissue patterning. While initially discovered and characterized in the model insect Drosophila melanogaster, recent studies across various insect species have revealed the broad involvement of Notch signaling in shaping insect tissues. This review focuses on providing a comprehensive picture regarding the roles of the Notch pathway in insect development. The roles of Notch in the formation and patterning of the insect embryo, wing, leg, ovary and several specific structures, as well as in physiological responses, are summarized. These results are discussed within the developmental context, aiming to deepen our understanding of the diversified functions of the Notch signaling pathway in different insect species.

show abstract