The experimental use of methylphenidate for hypothermia in patients with lewy body dementia

Baeyens, Hilde; Dekoninck, J.; Baeyens, Jean Pierre

doi:10.1016/j.eurger.2011.05.014

Cited by 1 publication

(1 citation statement)

References 4 publications

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“…Regarding the studies focused on patients with dementia, all participants had clinical improvement (Table 3 ). Four studies described trials aiming to evaluate the efficacy of methylphenidate in the treatment of apathy in patients with Alzheimer’s disease [ 43 - 46 ]; one study evaluated the efficacy of methylphenidate in the treatment of hypothermia in patients with dementia with Lewy’s bodies [ 47 ]; one case study assessed the efficacy of methylphenidate in the treatment of frontotemporal dementia [ 48 ] and finally, one trial assessed the efficacy of methylphenidate in patients with dementia and negative symptoms [ 49 ] which included reduced interest in self-care, work and home tasks, social and family interaction [ 50 ].…”

Section: Resultsmentioning

confidence: 99%

Amphetamine Use in the Elderly: A Systematic Review of the Literature

Sassi

Rocha

Colpo

et al. 2020

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Objective: To systematically review the literature on the therapeutic use of amphetamine, lisdexamfetamine and methylphenidate in elderly population with and without dementia. Methods: We conducted two researches on the PubMed, Scopus and Embase using the keywords (“elderly”) AND (“amphetamine” OR “methylphenidate” OR “lisdexamfetamine”) and then (“Alzheimer” OR “dementia”) AND (“amphetamine” OR “methylphenidate” OR “lisdexamfetamine”). Results: Twenty-nine papers met all the eligibility criteria. The results are encouraging as 81.5% of the studies showed clinical improvement of the investigated condition. Conclusion: Amphetamines and methylphenidate are probably effective strategies for different conditions in the elderly population. However, further studies are needed to provide more robust evidence on efficacy, dosage and safety for this population.

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