The excretion of trace elements in rat urine after treatment with 2,3-dimercaptopropane sodium sulfonate

DMSA and DMPS-Water Soluble Antidotes for Heavy Metal Poisoning

“…Procedures for synthesizing DMPS (3,10), DMSA (11), 35 S-DMSA (12,13), and [2,3-14 C]-DMSA (14) have been reported. DMSA and DMPS have been labeled with 99 Tc for use in renal scanning (15,16). DMPS is manufactured by Heyl & Co., Berlin, who distribute it as DIMAVAL ® .…”

“…More recently the effect of DMPS on trace metal excretion has been studied under more controlled conditions using the rat (99). A large dosedependent increase in urinary excretion of Zn and Cu was found during one 24 h period following a single administration of DMPS (0.025 to 1.0 mmols/kg).…”

DMSA and DMPS-Water Soluble Antidotes for Heavy Metal Poisoning

“…Procedures for synthesizing DMPS (3,10), DMSA (11), 35 S-DMSA (12,13), and [2,3-14 C]-DMSA (14) have been reported. DMSA and DMPS have been labeled with 99 Tc for use in renal scanning (15,16). DMPS is manufactured by Heyl & Co., Berlin, who distribute it as DIMAVAL ® .…”

“…More recently the effect of DMPS on trace metal excretion has been studied under more controlled conditions using the rat (99). A large dosedependent increase in urinary excretion of Zn and Cu was found during one 24 h period following a single administration of DMPS (0.025 to 1.0 mmols/kg).…”

DMSA and DMPS-Water Soluble Antidotes for Heavy Metal Poisoning

“…Procedures for synthesizing DMPS (3,10), DMSA (11), 35 S-DMSA (12,13), and [2,3-14 C]-DMSA (14) have been reported. DMSA and DMPS have been labeled with 99 Tc for use in renal scanning (15,16). DMPS is manufactured by Heyl & Co., Berlin, who distribute it as DIMAVAL ® .…”

“…More recently the effect of DMPS on trace metal excretion has been studied under more controlled conditions using the rat (99). A large dosedependent increase in urinary excretion of Zn and Cu was found during one 24 h period following a single administration of DMPS (0.025 to 1.0 mmols/kg).…”

DMSA and DMPS-Water Soluble Antidotes for Heavy Metal Poisoning

“…Procedures for synthesizing DMPS (3,10), DMSA (11), 35 S-DMSA (12,13), and [2,3-14 C]-DMSA (14) have been reported. DMSA and DMPS have been labeled with 99 Tc for use in renal scanning (15,16). DMPS is manufactured by Heyl & Co., Berlin, who distribute it as DIMAVAL ® .…”

“…More recently the effect of DMPS on trace metal excretion has been studied under more controlled conditions using the rat (99). A large dosedependent increase in urinary excretion of Zn and Cu was found during one 24 h period following a single administration of DMPS (0.025 to 1.0 mmols/kg).…”