The evolving field of Dermato‐oncology and the role of dermatologists: Position Paper of the EADO, EADV and Task Forces, EDF, IDS, EBDV–UEMS and EORTC Cutaneous Lymphoma Task Force

Garbe, Claus; Peris, Ketty; Soura, Efthymia; Forsea, Ana‐Maria; Hauschild, Axel; Arenberger, Petr; Bylaitė, Matilda; Marmol, Véronique Del; Bataille, Véronique; Samimi, Mahtab; Gandini, Sara; Saïag, Philippe; Eigentler, Thomas; Lallas, Aimilios; Zalaudek, Iris; Lebbe, Célèste; Grob, Jean‐Jacques; Höeller, Christoph; Robert, Caroline; Dréno, Brigitte; Kandolf-Sekulovic, Lidija; Kaufmann, Roland; Malvehy, Josep; Puig, Susana; Leiter, Ulrike; Ribero, Simone; Papadavid, E.; Quaglino, Pietro; Bagot, Martine; John, Swen Malte; Richard, M.‐A.; Trakatelli, M.; Sălăvăstru, Carmen; Borradori, Luca; Marinović, Branka; Enk, Alexander H.; Pincelli, Carlo; Ioannides, Demetrios; Paul, C.; Stratigos, Alexandros

doi:10.1111/jdv.16849

Cited by 24 publications

(26 citation statements)

References 107 publications

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“…The strength of this study lies in its unique approach and design as until to date no standard test method has been developed to assess other PA than the three mandatory efficacy statements. To our knowledge, this study has identified for the first time a specific test-battery for objectifying the suitability of appropriate sunscreen formulations and thus provided a significant impetus for the current scientific and political focus on improvement of occupational health in highly UVR-exposed OW [ 50 – 52 ]. Our study aims to open up a discussion on new testing methods focusing on outdoor workers’ expectations and the intended scope of application that complement the so far mandatory labels and assist in making informed, evidence-based decisions when choosing an appropriate sunscreen product.…”

Section: Discussionmentioning

confidence: 99%

New methods for assessing secondary performance attributes of sunscreens suitable for professional outdoor work

Rocholl

Weinert

Bielfeldt³

et al. 2021

J Occup Med Toxicol

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Background Outdoor workers (OW) are highly exposed to solar ultraviolet radiation (UVR) and thus at increased risk for developing skin cancer. An essential part of an overall strategy to reduce workplace UVR-exposure to OW’s skin is the usage of sunscreens. However, compliance with regular sunscreen usage seems to be low, as products are usually designed for recreational sun exposure and thus do not meet the requirements of physically active OW. To date, no standardized test procedures assess the suitability of sunscreens for professional use. The aim of this pilot study was to develop standardized methods of testing secondary performance attributes (PA) to represent real-life working conditions of outdoor work. Methods Ten sunscreen products, carefully selected after a detailed market survey of all relevant producers available on the German market, were evaluated regarding their suitability for professional outdoor work on 24 healthy volunteers in a newly designed test procedure. In addition to three standardized efficacy characteristics, i.e., sun protection factor, water-resistance, and UVA protection, we evaluated each PA involving parameters typically associated with outdoor workplaces. Results We developed standardized methods for objectifying the suitability of sunscreen products for professional outdoor work. The test procedures used are well feasible and appropriate for testing the PA because they represent practical working conditions in detail – although the degree of discriminability of single test methods varied. The claimed sun protection factor (SPF) of the products was confirmed; bio-stability of the SPF after physical activity was achieved in most cases. While most products hardly irritate the eyes and are quickly absorbed, the evaluation of the subjective skin feeling and non-slip grip is inconsistent. Conclusions In this pilot study, for the first time secondary PA are defined and examined. Although further objectification of the PA assessment as well as the establishment of minimum standards should be sought, the new methods could already complement the so far mandatory labels and in this way provide a significant impetus for the current scientific and political focus on the improvement of occupational health in highly UVR-exposed OW.

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Section: Discussionmentioning

confidence: 99%

New methods for assessing secondary performance attributes of sunscreens suitable for professional outdoor work

Rocholl

Weinert

Bielfeldt³

et al. 2021

J Occup Med Toxicol

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“…The increase in life expectancy and population ageing along with the introduction of in vivo diagnostic tools (e.g. dermoscopy) and new treatments for advanced melanoma and KCs have resulted in unprecedented changes in the organization of patient care in the clinical setting [ 7 ]. This generates a great burden on national healthcare systems and economies.…”

Section: Introductionmentioning

confidence: 99%

“…Secondary prevention encompasses the various strategies of early detection of skin tumors, including skin cancer screening programs. These strategies are expected to reduce the epidemiologic burden and the cost of skin cancer management–under the premise that skin cancer can be more easily and effectively treated at an early phase of development [ 7 ]. Dermatologists are the best trained and equipped specialists to provide early detection, but their success depends on patients receiving timely access to their services.…”

Section: Introductionmentioning

confidence: 99%

“…Dermatologists are the best trained and equipped specialists to provide early detection, but their success depends on patients receiving timely access to their services. In some countries, the lack of dermatologists has led to an increase in use of e-Health and teledermatology over the last 10 years [ 7 ]. Sensitivity has been found to be comparable between teledermatology associated with the use of dermoscopy and face-to-face evaluations, although specificity was higher in face-to-face evaluations [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

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Implementation of artificial intelligence algorithms for melanoma screening in a primary care setting

et al. 2021

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Skin cancer is currently the most common type of cancer among Caucasians. The increase in life expectancy, along with new diagnostic tools and treatments for skin cancer, has resulted in unprecedented changes in patient care and has generated a great burden on healthcare systems. Early detection of skin tumors is expected to reduce this burden. Artificial intelligence (AI) algorithms that support skin cancer diagnoses have been shown to perform at least as well as dermatologists’ diagnoses. Recognizing the need for clinically and economically efficient means of diagnosing skin cancers at early stages in the primary care attention, we developed an efficient computer-aided diagnosis (CAD) system to be used by primary care physicians (PCP). Additionally, we developed a smartphone application with a protocol for data acquisition (i.e., photographs, demographic data and short clinical histories) and AI algorithms for clinical and dermoscopic image classification. For each lesion analyzed, a report is generated, showing the image of the suspected lesion and its respective Heat Map; the predicted probability of the suspected lesion being melanoma or malignant; the probable diagnosis based on that probability; and a suggestion on how the lesion should be managed. The accuracy of the dermoscopy model for melanoma was 89.3%, and for the clinical model, 84.7% with 0.91 and 0.89 sensitivity and 0.89 and 0.83 specificity, respectively. Both models achieved an area under the curve (AUC) above 0.9. Our CAD system can screen skin cancers to guide lesion management by PCPs, especially in the contexts where the access to the dermatologist can be difficult or time consuming. Its use can enable risk stratification of lesions and/or patients and dramatically improve timely access to specialist care for those requiring urgent attention.

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“…Despite the fact that it comprises a group of preventable diseases with known risk factors [ 9 ], a 45-fold increase of melanoma (and 80-fold of non-melanoma skin cancers) is expected over 8 decades. Australia is probably the only country that has managed to change this negative trend of melanoma incidence [ 14 ].…”

mentioning

confidence: 99%

Neglected malignant neoplasms with cutaneous involvement

Kamińska‐Winciorek

Cybulska-Stopa

Gajda

et al. 2021

pdia

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The evolving field of Dermato‐oncology and the role of dermatologists: Position Paper of the EADO, EADV and Task Forces, EDF, IDS, EBDV–UEMS and EORTC Cutaneous Lymphoma Task Force

Cited by 24 publications

References 107 publications

New methods for assessing secondary performance attributes of sunscreens suitable for professional outdoor work

New methods for assessing secondary performance attributes of sunscreens suitable for professional outdoor work

Implementation of artificial intelligence algorithms for melanoma screening in a primary care setting

Neglected malignant neoplasms with cutaneous involvement

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