The ethanol extract of Leonurus sibiricus L. induces antioxidant, antinociceptive and topical anti-inflammatory effects

Oliveira, Alan Santos; Cercato, Luana Mendonça; Souza, Marília Trindade de Santana; Melo, Allan John de Oliveira; Lima, Bruno dos Santos; Duarte, Marcelo Cavalcante; Araújo, Adriano Antunes de Souza; Silva, Ana Mara de Oliveira e; Camargo, Enilton A.

doi:10.1016/j.jep.2017.05.029

Cited by 31 publications

(30 citation statements)

References 45 publications

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“…The wettability studies demonstrated that the functionalised mesoporous carbon surface had superior hydrophilic properties as compared against the non-functionalised mesoporous carbon film surface. In a related study Gao et al [152] also has developed a boron-doped mesoporous carbons (BOMCs) for making of super-capacitors. Different boron contents were prepared by nano-casting using silica KIT-6, FA and boric acid as the template, carbon, and boron sources respectively.…”

Section: Sundry Applicationsmentioning

confidence: 99%

Furfuryl Alcohol a Versatile, Eco-Sustainable Compound in Perspective

Iroegbu

Hlangothi

2018

Chemistry Africa

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Renewable agricultural biomass derived chemicals, their modifications and uses have seen multiplicity in numerous applications and important processes with major impacts on the pursuit for eco-sustainability. Such applications range include the energy sector, chemistry, pharmacy, the textile industry, paints and coatings, plastic industry, to name but a few. This field of lignocellulosic derived chemicals interconnects several scientific disciplines ranging from agriculture, biochemistry, engineering, environmental sciences, forestry, pharmacy, medicine, etc. hence making it difficult to have a single expert view on these complicated interactions. Therefore, the idea to create a focused review, specifically, on FA (an important furanic compound) is the main objective of this article. FA and its resultant derivatives exhibits an array of capabilities and fascinating properties in various fields of applications. As a compound or with co-reactants, it finds interesting applications as base and/or intermediate chemical compound, hypergolic rocket fuels, in flame resistant composites and coatings used in aerospace, auto, and the built environment; it also finds application as mortars, cementitious grouts, impregnating materials, and sealants due to its exceptional resistance to common corrosive chemicals such as acids, alkalis and other solvents when it is cross-linked. Coupled with its environmental and economic benefits FA has proved to be a remarkable eco-sustainable bio-derived compound.

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Section: Sundry Applicationsmentioning

confidence: 99%

Furfuryl Alcohol a Versatile, Eco-Sustainable Compound in Perspective

Iroegbu

Hlangothi

2018

Chemistry Africa

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“…An ABTS + solution was prepared through the reaction of 7.0 mM (3.6 mg/mL) ABTS and 2.45 mM (662.28 mg/mL) potassium persulphate, which were incubated at RT in the dark for 16 h [28]. The ABTS + solution was then diluted with 80% ethanol to obtain an absorbance of 0.7 ± 0.01 at 734 nm [29]. Stock solutions of 10 mg/mL of LM and FM in 80% ethanol were prepared.…”

Section: Phytochemical Screeningmentioning

confidence: 99%

In Vivo Evaluation of Antirrhinum majus’ Wound-Healing Activity

2018

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Mediterranean-native perennial plant Antirrhinum majus was scrutinized in this study for its antioxidant activity and its total phenolic content in order to test for the plant’s wound-healing capability. The traditional uses of this plant to treat gum scurvy, various tumors, ulcers, and hemorrhoids were the main idea behind this study. Leaves and flowers of the A. majus were extracted by maceration. Pilot qualitative phytochemical tests were made to check the presence of various secondary metabolites. Quantitatively, the flowers’ macerate indicated superlative results regarding antioxidant activity and total phenolic content. However, the in vivo wound-healing capability study was made using 30 Wistar strain albino rats. This innovative part of the study revealed that the healing power of the flowers’ extract ointment (5% w/w) was superior compared to the leaves’ extract (5% w/w) and the positive-control ointments (MEBO) (1.5% w/w) (p ≤ 0.001). This activity was assessed by visual examination, wound-length measurement, and estimation of hydroxyproline content. Antirrhinum majus is a promising plant to be considered for wound healing. However, further testing (including histological examination and high-performance liquid chromatography (HPLC) analysis) is necessary to understand more about its mechanisms of action.

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“…1 In China, LJ is an abundant resource, and the production of LJ is nearly hundreds of thousands of tons. 2 In 1990, LJ was added to the Pharmacopoeia of the People's Republic of China. According to preliminary statistics, more than 300 prescriptions containing LJ have been adopted to treat many diseases, especially those interfering with blood coagulation, in China.…”

Section: Introductionmentioning

confidence: 99%

“…As a traditional Chinese herbal medicine, previous reports and our preliminary experiments simultaneously proved that LJ possesses both high antioxidant and remarkable anticoagulation activities. 1,2 However, to date, there have been few studies on the connection between the effects of antioxidant and anticoagulation compounds in LJ. Additionally, LJ is inexpensive and readily available, and it is generally considered as waste in the areas in which it is produced.…”

Section: Introductionmentioning

confidence: 99%