The EPTN consensus-based atlas for CT- and MR-based contouring in neuro-oncology

Eekers, Daniëlle; Ven, Lieke in ’t; Roelofs, Erik; Postma, Alida A.; Alapetite, Claire; Burnet, N.G.; Calugaru, Valentin; Compter, Inge; Coremans, I.; Høyer, M.; Lambrecht, Maarten; Nyström, Petra Witt; Romero, Alejandra Méndez; Paulsen, Frank; Perpar, Ana; Ruysscher, Dirk De; Renard, Laurette; Timmermann, Beate; Vítek, Pavel; Weber, Damien Charles; Weide, H. L. van der; Whitfield, Gillian A; Wiggenraad, Ruud; Troost, Esther G.C.

doi:10.1016/j.radonc.2017.12.013

Cited by 102 publications

(83 citation statements)

References 59 publications

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“…Biconvex structure in the aqueous humor, it is clearly visible in CT [2]. The structure is about 10 mm in diameter seen in the coronal plane.…”

Section: Lensmentioning

confidence: 90%

“…For contouring of substructures of the eye the European particle therapy network (EPTN) has put forward a consensus based atlas based on CT and MRI [2].…”

Section: Optic Structures 21 Eye Ballmentioning

confidence: 99%

“…The cornea is located anterior to the vitreous humor, iris, lens and ciliary body [2]. It can be delineated in MRI or CT and is contoured with a 2-3 mm brush.…”

Section: Corneamentioning

confidence: 99%

“…It is the innermost layer of the globe and is about 0.25 mm in thickness and is not usually visualized in a standard MRI [2]. Contoured using a 3 mm brush, the retina covers the posterior 5/6th of the globe.…”

Section: Retinamentioning

confidence: 99%

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Overview of Important “Organs at Risk” (OAR) in Modern Radiotherapy for Head and Neck Cancer (HNC)

Basu¹,

Bhaskar²

2019

Cancer Survivorship

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With the advent of highly conformal and adaptive radiotherapy techniques, the significance of accurate delineation of organs at risk (OARs) is becoming more and more important. Techniques such as Intensity modulated radiotherapy (IMRT) and intensity/ volumetric modulated arc therapy (VMAT) has allowed for improved dose conformation within the target. It has also allowed for steep dose gradients around the target for better normal tissue sparing. The accurate contouring and delineation of the OARs are thus warranted as variation in delineation has been systematically reported in studies. All these facts have led to the development of contouring guidelines for OARs in various sites. Head and neck cancers (HNC) are a perfect example where outcome and quality of life (QOL) balance remains a therapeutic challenge. There are several OARs and thus the accurate delineation following a standard guideline becomes more important. This chapter looks into the published guidelines for the delineation of such structures.

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“…Biconvex structure in the aqueous humor, it is clearly visible in CT [2]. The structure is about 10 mm in diameter seen in the coronal plane.…”

Section: Lensmentioning

confidence: 90%

“…For contouring of substructures of the eye the European particle therapy network (EPTN) has put forward a consensus based atlas based on CT and MRI [2].…”

Section: Optic Structures 21 Eye Ballmentioning

confidence: 99%

“…The cornea is located anterior to the vitreous humor, iris, lens and ciliary body [2]. It can be delineated in MRI or CT and is contoured with a 2-3 mm brush.…”

Section: Corneamentioning

confidence: 99%

Section: Retinamentioning

confidence: 99%

See 2 more Smart Citations

Overview of Important “Organs at Risk” (OAR) in Modern Radiotherapy for Head and Neck Cancer (HNC)

Basu¹,

Bhaskar²

2019

Cancer Survivorship

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“…Therefore, EPTN is an official task force of the European Society for Radiotherapy and Oncology (ESTRO). The seven working groups have already produced a series of recommendations and whitepapers, and more activities are expected in the coming years (Bolsi et al, 2018;Dosanjh et al, 2018b;Eekers et al, 2018;Grau et al, 2018;Lambrecht et al, 2018;Langendijk et al, 2018b;Weber et al, 2018Weber et al, , 2019.…”

Section: Collaborative Networkmentioning

confidence: 99%

Particle therapy in Europe

et al. 2020

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Particle therapy using protons or heavier ions is currently the most advanced form of radiotherapy and offers new opportunities for improving cancer care and research. Ions deposit the dose with a sharp maximum – the Bragg peak – and normal tissue receives a much lower dose than what is delivered by X‐ray therapy. Particle therapy has also biological advantages due to the high linear energy transfer of the charged particles around the Bragg peak. The introduction of particle therapy has been slow in Europe, but within the last decade, more than 20 clinical facilities have opened and facilitated access to this frontline therapy. In this review article, the basic concepts of particle therapy are reviewed along with a presentation of the current clinical indications, the European clinical research, and the established networks.

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Proton therapy and/or helical tomotherapy for locally advanced sinonasal skull base adenoid cystic carcinoma: Focus on experience of the Institut Curie and review of literature

et al. 2023

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Background: Sinonasal adenoid cystic carcinomas (SNACC) have high propensity for skull base (SB) infiltration. Unresectability or incomplete surgical resection in such cases make radiotherapy treatment paramount. Curative dose escalation is challenging because of adjacent organs at risk, especially in locally advanced cases.Methods: Eighteen patients that had locally advanced SB SNACC with unresectable or incomplete surgical resection treated by proton therapy and/or helical tomotherapy at Institut Curie between 3/2010 and 8/2020 were retrospectively included. Results: After median follow-up of 52 months, 5-year OS, LRRFS, DMFS, DFS rates were, respectively, 47% (95%CI: 26-83), 50% (95%CI: 36-88), 39% (95%CI: 26-81), 33% (95%CI: 22-73). One patient had grade 4 late optic nerve disorder.Eight patients had grade 3 late toxicity including mainly hearing impairments. Conclusion:Proton therapy and helical tomotherapy are effective and safe methods for curative dose escalation of locally advanced SB SNACC, which are a poor prognosis subgroup. Available literature suggests carbon-ion therapy could be an efficient alternative.

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The EPTN consensus-based atlas for CT- and MR-based contouring in neuro-oncology

Cited by 102 publications

References 59 publications

Overview of Important “Organs at Risk” (OAR) in Modern Radiotherapy for Head and Neck Cancer (HNC)

Overview of Important “Organs at Risk” (OAR) in Modern Radiotherapy for Head and Neck Cancer (HNC)

Particle therapy in Europe

Proton therapy and/or helical tomotherapy for locally advanced sinonasal skull base adenoid cystic carcinoma: Focus on experience of the Institut Curie and review of literature

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