volume 66, issue 9, P5500-5508 1992
DOI: 10.1128/jvi.66.9.5500-5508.1992
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Abstract: Rta, encoded by Epstein-Barr virus (EBV), is a potent activator of transcription via enhancer sequences located upstream of several viral genes. To identify the domains of Rta that facilitate transcription by interacting with cellular transcription factors, different segments of Rta were linked to the DNA binding domain of yeast transactivator GAL4 (residues 1 to 147). These GALA-Rta fusion proteins were tested in transfected cells for their ability to activate the adeno Elb promoter with an upstream GALA DNA …

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