The Electrolyte Content of Skeletal Muscle in Congestive Heart Failure; A Comparison of Results With Inulin and Chloride as Reference Standards for Extracellular Water 1

An Evaluation of Radiosulfate for the Determination of the Volume of Extracellular Fluid in Man and Dogs 1

“…space with the tissue space of other referent substances (51)(52)(53)(54)(55). These studies have shown that varying portions of the -chloride space, notably in connective tissue, are impenetrable to sulfate (47,55), thiosulfate (51), and inulin (51)(52)(53)(54). Radiosulfate also fails to penetrate about 25 per cent of the chloride space of muscle (41).…”

The Distribution of Intravenously-Injected Inulin in the Fluids of the Nervous System of the Dog and Rat*

“…Unfortunately, there is no detailed account of the degree of penetration of nervous tissues by inulin in the living animal. This is surprising in view of the amount of information relating to the distribution of inulin in the fluids of other tissues such as muscle (2)(3)(4)(5). Allen (6) has determined the volume of distribution of inulin in tissue slices of brain by immersing them in solutions of inulin long enough for diffusion to take place and then estimating the inulin content of the slices.…”

The Effect of Potassium Chloride on Hyponatremia 1

“…Analyses of biopsy specimens of skeletal muscle of hyponatremic patients in congestive heart failure suggest that there may be more sodium and less potassium than normal within cells (3,26). However, the reported data are not altogether consistent (27). Other investigators (1,(28)(29)(30) have reported retention of potassium in excess of nitrogen in patients recovering from congestive heart failure.…”