“…Papillomaviruses also can be associated with pigmented plaques and in some cases squamous cell carcinoma . Viral papillomas often regress without treatment, but for those that do not regress, treatment with surgery, laser therapy, cryotherapy, systemic retinoids, azithromycin, imiquimod, interferon‐alpha2a (IFN‐ α2a), autologous or recombinant papillomavirus vaccine and homeopathic tarantula venom have been reported anecdotally . There is no recommended treatment appropriate for all affected dogs.…”