The efficacy of probiotics in prevention of urinary tract infection in children: A systematic review and meta-analysis

Hosseini, Mostafa; Yousefifard, Mahmoud; Ataei, Neamatollah; Oraii, Alireza; Razaz, Jalaledin Mirzay; Izadi, Anahita

doi:10.1016/j.jpurol.2017.08.018

Cited by 31 publications

(22 citation statements)

References 26 publications

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“…In the meta‐analysis, the high heterogeneities might be due to (i) the diversity of strains; (ii) the heterogeneity of study populations; (iii) the varied sample sizes; (iv) the different experimental designs; (v) the different treatment periods; (xi) the difference in the response of individuals; (xii) the different diets. Our explanations for the high heterogeneities in the study were also confirmed by the previous meta‐analyses with high heterogeneities on probiotics affecting different diseases …”

Section: Discussionsupporting

confidence: 86%

“…Probiotics, defined as ‘live microorganisms which when administered in adequate amounts confer a health benefit on the host’, have been used to treat a wide range of diseases . Alatriste et al investigated that the administration of probiotics in 30 CKD patients at stage 3–4 contributed to a reduction in serum urea level.…”

Section: Discussionmentioning

confidence: 99%

“…Probiotics, defined as 'live microorganisms which when administered in adequate amounts confer a health benefit on the host', have been used to treat a wide range of diseases. [30][31][32] Alatriste et al 33 investigated that the administration of probiotics in 30 CKD patients at stage 3-4 contributed to a reduction in serum urea level. Ranganathan et al 34 reported that the increase of urea was significantly retarded in stage 3-4 CKD patients while uric acid and creatinine showed no significant difference compared to placebo.…”

Section: Discussionmentioning

confidence: 99%

“…Our explanations for the high heterogeneities in the study were also confirmed by the previous meta-analyses with high heterogeneities on probiotics affecting different diseases. [30][31][32] To the best of our knowledge, this is the first metaanalysis exploring effects of probiotic supplements on CKD progression reporting comprehensive outcomes. Recently, one meta-analysis 48 including seven studies demonstrated potential beneficial effects of probiotics on uremic toxins, inflammation and gastrointestinal symptoms in dialysis patients.…”

Section: Discussionmentioning

confidence: 99%

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Effects of probiotic supplements on the progression of chronic kidney disease: A meta‐analysis

et al. 2019

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Background Chronic kidney disease (CKD) is a worldwide public health problem. Although accumulated data suggested that probiotic supplements played roles in CKD, the results remained controversial. Here, we performed a meta‐analysis to assess the effects of probiotic supplements on the CKD progression. Methods A systematic search was conducted through the PubMed, Embase and Cochrane databases until September 2018. Randomized controlled trials with control receiving placebo, evaluating the effects of probiotic supplements on CKD were included. Results A total of 10 randomized controlled trials in 8 countries were selected. In the meta‐analysis, urea level was significantly reduced in probiotics‐administrated non‐dialysis patients (mean differences (MD) = −30.01; 95% confidence interval (CI) = [−56.78, −3.25]; P = 0.03) while no significant change was found in the dialysis patients receiving probiotics (MD = 0.1; 95% CI = [−9.28, 9.48]; P = 0.98). Probiotic supplements also exhibited no effect on uric acid (MD = −0.43; 95% CI = [−1.19, 0.33]; P = 0.27), C‐reactive protein (MD = −0.48; 95% CI = [−1.29, 0.33]; P = 0.24), creatinine (MD = −0.18; 95% CI = [−0.82, 0.47]; P = 0.59), and estimated glomerular filtration rate (MD = 2.10; 95% CI = [−1.31, 5.52]; P = 0.23) of CKD patients. Conclusion Our results highlighted that probiotic supplements exerted a statistically significant effect on urea levels in non‐dialysis CKD population, while no evidence suggested that probiotics possessed meaningful impacts on the reduction of uric acid, C‐reactive protein, creatinine and estimated glomerular filtration rate preservation of CKD population.

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Section: Discussionsupporting

confidence: 86%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Effects of probiotic supplements on the progression of chronic kidney disease: A meta‐analysis

et al. 2019

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“…The prevalence of this type of infection is different in different cities of Iran and is reported from 4 to 12%. The prevalence in girls is 77.2% more than boys and in terms of age, the highest prevalence is in the age group under 1 year old [9][10][11]. Out of 250 children with urinary tract infections aged 1 to 12 months who referred to Amir Kabir Hospital in Arak, 224 (89.6%) were girls and 26 (10.4%) were boys and the highest percentage was observed in girls [12].…”

Section: Introductionmentioning

confidence: 99%

The effect of educational intervention program on promoting preventive behaviors of urinary tract infection in girls: a randomized controlled trial

et al. 2020

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Background: Urinary tract infection is one of the most common infectious diseases in children, which can lead to serious complications for a child. The purpose of this study was to investigate the impact of Theory Planned Behavior (TPB)-based education on the promotion of preventive behaviors of urinary tract infection in mothers with a daughter under age two. Methods: The present study is an educational randomized controlled trial that its sample consisted of 100 mothers who had a daughter under age two. They were selected through convenience sampling and then were randomly assigned to the intervention and control groups (each group included 50 participants). The data collection tool was a reliable and valid questionnaire based on TPB constructs. First, in both groups, the pre-test was administrated and then the educational intervention in the intervention group was conducted in the form of four educational sessions in 1 month (based on the pre-test need assessment) and then 3 months after the intervention (according to the ideas of Panel of Experts), post-test in both groups was administrated and then the data were analyzed through SPSS version 23 software with inferential statistics (independent t-test, paired t-test, and chi-square). The significance level was considered 0.05. Results: Three months after the intervention, the mean score of the constructs of TPB in the intervention group was significantly higher than the control group. The performance of prevention of urinary tract infection in the intervention group before the education increased from 2.85 ± 0.51 to 3.74 ± 0.29 (out of 4) (p = 0.001). Conclusions: TPB-based education with active and interventional follow-up was effective in promoting the preventive behaviors of urinary tract infection. Therefore, due to the side effects of UTI, especially in vulnerable periods such as childhood, it is recommended that trainings based on this model be carried out in other health care centers in order to maintain children health.

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Probiotics and Infection Prevention

Chan,

Perry,

Doron

2022

Infection Prevention

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The efficacy of probiotics in prevention of urinary tract infection in children: A systematic review and meta-analysis

Cited by 31 publications

References 26 publications

Effects of probiotic supplements on the progression of chronic kidney disease: A meta‐analysis

Effects of probiotic supplements on the progression of chronic kidney disease: A meta‐analysis

The effect of educational intervention program on promoting preventive behaviors of urinary tract infection in girls: a randomized controlled trial

Probiotics and Infection Prevention

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