2014
DOI: 10.1186/s13018-014-0090-7 View full text |Buy / Rent full text
|
|

Abstract: PurposeTotal knee arthroplasty (TKA) is a popular procedure in severe osteoarthritis. But perioperative bleeding remains a problem. Floseal® is a mixture of thrombin and bovine gelatin which can benefit a lot on reducing intraoperative and postoperative bleeding. However, there is no enough evidence judging its safety and efficiency. So a meta-analysis is conducted by us to evaluate the efficacy and safety of a thrombin-based hemostatic agent compared with conventional methods in TKA.MethodTwo independent revi… Show more

Help me understand this report

Search citation statements

Order By: Relevance
Select...
3
2
15
0

Year Published

2016
2016
2016
2016

Publication Types

Select...
4

Relationship

2
2

Authors

Journals

2
15
0
Order By: Relevance
“…The literature available on other hemostatic agents generally does not suggest increased morbidity subsequent to the use of Floseal, Surgicel or Fibrillar. A meta‐analysis in 2014 evaluating the efficacy of Floseal in total knee arthroplasty patients found no differences in postoperative drainage volume, incidence of wound infection, deep vein thrombosis and pulmonary embolism between Floseal and controls . Similarly, a study comparing post‐thyroidectomy bleeding and infection rates of 98 patients who received Surgicel vs. 92 patients who did not receive Surgicel found similar outcomes .…”
Section: Discussionmentioning
Create an account to read the remaining citation statements from this report. You will also get access to:
  • Search over 1.2b+ citation statments to see what is being said about any topic in the research literature
  • Advanced Search to find publications that support or contrast your research
  • Citation reports and visualizations to easily see what publications are saying about each other
  • Browser extension to see Smart Citations wherever you read research
  • Dashboards to evaluate and keep track of groups of publications
  • Alerts to stay on top of citations as they happen
  • Automated reference checks to make sure you are citing reliable research in your manuscripts
  • 7 day free preview of our premium features.

Trusted by researchers and organizations around the world

Over 130,000 students researchers, and industry experts at use scite

See what students are saying

rupbmjkragerfmgwileyiopcupepmcmbcthiemesagefrontiersapsiucrarxivemeralduhksmucshluniversity-of-gavle
“…The literature available on other hemostatic agents generally does not suggest increased morbidity subsequent to the use of Floseal, Surgicel or Fibrillar. A meta‐analysis in 2014 evaluating the efficacy of Floseal in total knee arthroplasty patients found no differences in postoperative drainage volume, incidence of wound infection, deep vein thrombosis and pulmonary embolism between Floseal and controls . Similarly, a study comparing post‐thyroidectomy bleeding and infection rates of 98 patients who received Surgicel vs. 92 patients who did not receive Surgicel found similar outcomes .…”
Section: Discussionmentioning
“…Recently, hemostatic agents such as Floseal hemostatic matrix (Baxter International, Chicago, IL, USA), aprotinin and TXA have attracted our attention because of their high efficiency and cost‐effectiveness, as reported in several studies. TXA, a known antifibrinolytic agent, has commonly been used in surgical procedures because of its low cost and allergenicity.…”
Section: Discussionmentioning
“…In the previous meta-analysis, Wang et al analyzed the efficacy of Floseal in primary TKA. 1 Their review demonstrated that the use of Floseal decreased hemoglobin decline and calculated total blood loss, and did not increase the risk of DVT and pulmonary embolism (PE). However, their findings were limited by a low level of evidence; the review was based largely on RCTs, prospective controlled trials, and case controlled trials.…”
Section: Discussionmentioning