2014
DOI: 10.1371/journal.pone.0099646
View full text |Buy / Rent full text
|
Sign up to set email alerts
|

Abstract: BackgroundThe effects of vitamin D supplementation on mild hepatic dysfunction and glycemic control are unclear in children and adolescents with either type 1 (T1D) or type 2 diabetes (T2D).HypothesisVitamin D supplementation will improve hepatic dysfunction and glycemic control.AimTo determine the effect of vitamin D supplementation on alanine transaminase (ALT), hemoglobin A1c (HbA1c), and serum 25-hydroxyvitamin D [25(OH)D] concentration.Subjects and MethodsA retrospective study of 131 subjects with either … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

2
42
0
4

Year Published

2015
2015
2018
2018

Publication Types

Select...
5

Relationship

1
4

Authors

Journals

citations
Cited by 48 publications
(48 citation statements)
references
References 63 publications
(67 reference statements)
2
42
0
4
Order By: Relevance
“…Furthermore, epidemiological studies, in patients with T2DM show a significant relationship between low 25OHD levels and reduced glucose tolerance [3436]. …”
Section: Discussionmentioning
confidence: 99%
“…Furthermore, epidemiological studies, in patients with T2DM show a significant relationship between low 25OHD levels and reduced glucose tolerance [3436]. …”
Section: Discussionmentioning
confidence: 99%
“…As detailed in Nwosu et al[22], the diagnosis of type 1 diabetes was based on any of the following glycemic parameters: a fasting blood glucose of ≥ 7 mmol/L (126 mg/dL), and/or 2-hour postprandial glucose of ≥11.1 mmol/L (200 mg/dL), and/or random blood glucose of ≥11.1 mmol/L (200 mg/dL) with symptoms of polyuria and/or polydipsia. Additionally, subjects were positive for one or more diabetes-associated auto-antibodies, including insulin autoantibodies, islet cell cytoplasmic autoantibodies, glutamic acid decarboxylase antibodies, and/or insulinoma associated-2 (IA-2A) autoantibodies.…”
Section: Methodsmentioning
confidence: 99%
“…37 During normal pregnancy, the maternal adaptive immune system is suppressed whereas the innate immune system is relatively stimulated. 49 Effects of VDD in pregnancy have been associated with some adverse pregnancy outcomes, such as preeclampsia, gestational diabetes, fetal growth restriction, maternal infections, and preterm labor. 38,39 Normal pregnancy is characterized by a shift in immune response from type 1 to type 2.…”
Section: Introductionmentioning
confidence: 99%