The effects of time-varying curvature on velocity profiles in a model of the coronary arteries

Schilt, Stephan; Moore, James E.; Delfino, A.; Meister, Jean-Jacques

doi:10.1016/0021-9290(95)00082-8

Cited by 34 publications

(14 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Recently, there have been some debates as to what degree of WSS or large WSS gradients is contributory to the onset of plaque formation and rupture at the same time. Various studies have gone into explaining how regions are differentiated into varying degrees of WSS and link their implications to vessel narrowing [3,32,14,36]. It is widely available in these literatures that atherosclerotic plaques are located at low WSS and wall pressure gradient (WPG) regions, and it is accepted that local hemodynamic forces play an important role in the formation and rupture of atherosclerotic plaques.…”

Section: Introductionmentioning

confidence: 99%

Hemodynamic characterization of transient blood flow in right coronary arteries with varying curvature and side-branch bifurcation angles

Liu

Ghista

et al. 2015

Computers in Biology and Medicine

View full text Add to dashboard Buy / Rent full text

Section: Introductionmentioning

confidence: 99%

Hemodynamic characterization of transient blood flow in right coronary arteries with varying curvature and side-branch bifurcation angles

Liu

Ghista

et al. 2015

Computers in Biology and Medicine

View full text Add to dashboard Buy / Rent full text

“…In addition, the motion had more drastic changes on shear rate during systole. 18 Schilt et al 25 experimentally investigated the effects of time-varying curvature in a uniformly curved tube. Their in vitro model utilized a flexible curved tube through which fluid flowed under a steady imposed pressure gradient.…”

Section: Introductionmentioning

confidence: 99%

“…The results showed that the axial velocity profile was skewed towards the outer wall due to the curvature and was controlled in shape by the dynamics of the curvature change. 25 More recent studies on coronary artery movement have taken a computational fluid dynamics (CFD) modeling approach. In one such CFD model, Santamarina et al studied the significance of dynamic curvature changes on the flow-induced shear stresses on the coronary artery walls.…”

Section: Introductionmentioning

confidence: 99%

Fluid Dynamic Analysis in a Human Left Anterior Descending Coronary Artery with Arterial Motion

et al. 2004

View full text Add to dashboard Buy / Rent full text

A computational fluid dynamic (CFD) analysis is pre sented to describe local flow dynamics in both 3-D spatial and 4-D spatial and temporal domains from reconstructions of intravascular ultrasound (IVUS) and bi-plane angiographic fusion images. A left anterior descending (LAD) coronary artery segment geometry was accurately reconstructed and subsequently its motion was incorporated into the CFD model. The results indicate that the incorporation of motion had appreciable effects on blood flow patterns. The velocity profiles in the region of a stenosis and the circumferential distribution of the axial wall shear stress (WSS) patterns in the vessel are altered with the wall motion introduced in the simulation. The time-averaged axial WSS between simulations of steady flow and unsteady flow without arterial motion were comparable (-0.3 to 13.7 Pa in unsteady flow versus -0.2 to 10.1 Pa in steady flow) while the magnitudes decreased when motion was introduced (0.3-4.5 Pa). The arterial wall motion affects the time-mean WSS and the oscillatory shear index in the coronary vessel fluid dynamics and may provide more realistic predictions on the progression of atherosclerotic disease.

show abstract

“…Murata, Miyake & Inaba (1976) studied steady flow in pipes with zero torsion and non-uniform curvature, and found that the Reynolds number affects the position of the maximum axial velocity. Other features that have been studied include arterial movement (Lynch, Waters & Pedley 1996;Schilt et al 1996;Waters 1996), taper (Grotberg 1984), bifurcation, and elasticity (see the review by Pedley 1995).…”

Section: Introductionmentioning

confidence: 99%

Flow in pipes with non-uniform curvature and torsion

Gammack

Hydon

2001

J. Fluid Mech.

View full text Add to dashboard Buy / Rent full text

This paper describes steady and unsteady flows in pipes with small, slowly varying curvature and torsion. Four new pipe shapes are studied, using Germano's extension of the Dean equations. Analytic and numerical solutions are obtained for flows driven by a steady pressure gradient. Oscillatory flows in pipes with non-uniform curvature are obtained by numerical methods. The effects of the non-uniformities in curvature and torsion are discussed, with particular reference to wall shear stress.

show abstract

The effects of time-varying curvature on velocity profiles in a model of the coronary arteries

Cited by 34 publications

References 8 publications

Hemodynamic characterization of transient blood flow in right coronary arteries with varying curvature and side-branch bifurcation angles

Hemodynamic characterization of transient blood flow in right coronary arteries with varying curvature and side-branch bifurcation angles

Fluid Dynamic Analysis in a Human Left Anterior Descending Coronary Artery with Arterial Motion

Flow in pipes with non-uniform curvature and torsion

Contact Info

Product

Resources

About