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Cited by 34 publications
(14 citation statements)
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“…Recently, there have been some debates as to what degree of WSS or large WSS gradients is contributory to the onset of plaque formation and rupture at the same time. Various studies have gone into explaining how regions are differentiated into varying degrees of WSS and link their implications to vessel narrowing [3,32,14,36]. It is widely available in these literatures that atherosclerotic plaques are located at low WSS and wall pressure gradient (WPG) regions, and it is accepted that local hemodynamic forces play an important role in the formation and rupture of atherosclerotic plaques.…”
Section: Introductionmentioning
confidence: 99%
“…Recently, there have been some debates as to what degree of WSS or large WSS gradients is contributory to the onset of plaque formation and rupture at the same time. Various studies have gone into explaining how regions are differentiated into varying degrees of WSS and link their implications to vessel narrowing [3,32,14,36]. It is widely available in these literatures that atherosclerotic plaques are located at low WSS and wall pressure gradient (WPG) regions, and it is accepted that local hemodynamic forces play an important role in the formation and rupture of atherosclerotic plaques.…”
Section: Introductionmentioning
confidence: 99%
“…In addition, the motion had more drastic changes on shear rate during systole. 18 Schilt et al 25 experimentally investigated the effects of time-varying curvature in a uniformly curved tube. Their in vitro model utilized a flexible curved tube through which fluid flowed under a steady imposed pressure gradient.…”
Section: Introductionmentioning
confidence: 99%
“…The results showed that the axial velocity profile was skewed towards the outer wall due to the curvature and was controlled in shape by the dynamics of the curvature change. 25 More recent studies on coronary artery movement have taken a computational fluid dynamics (CFD) modeling approach. In one such CFD model, Santamarina et al studied the significance of dynamic curvature changes on the flow-induced shear stresses on the coronary artery walls.…”
Section: Introductionmentioning
confidence: 99%
“…Murata, Miyake & Inaba (1976) studied steady flow in pipes with zero torsion and non-uniform curvature, and found that the Reynolds number affects the position of the maximum axial velocity. Other features that have been studied include arterial movement (Lynch, Waters & Pedley 1996;Schilt et al 1996;Waters 1996), taper (Grotberg 1984), bifurcation, and elasticity (see the review by Pedley 1995).…”
Section: Introductionmentioning
confidence: 99%