The effects of omega-3 fatty acids and vitamin E co-supplementation on clinical and metabolic status in patients with Parkinson's disease: A randomized, double-blind, placebo-controlled trial

Protection from the Pathogenesis of Neurodegenerative Disorders, including Alzheimer’s Disease, Amyotrophic Lateral Sclerosis, Huntington’s Disease, and Parkinson’s Diseases, through the Mitigation of Reactive Oxygen Species

“…One study consisting of 2,866 patients with Parkinson's disease and 2,734 healthy controls observed that increased serum vitamin D levels reduced the severity of progression of PD [174]. A regular intake of foods rich in vitamin E may also defer the development or even lower the risk of PD [175]. In fact, vitamin E is a scavenger of several ROS and serves to reduce their reactivity and toxicity [79,[175][176][177].…”

“…A regular intake of foods rich in vitamin E may also defer the development or even lower the risk of PD [175]. In fact, vitamin E is a scavenger of several ROS and serves to reduce their reactivity and toxicity [79,[175][176][177]. A study that administered a combination of vitamins C and E to patients in the early stages of PD found that the vitamin regimen slowed the progression of PD [178].…”

“…Omega-3 fatty acids act as free radical scavengers and reduce ROS formation [180]. They also decrease the chemotaxis of monocytes and neutrophils and curb the formation of pro-in lammatory cytokines [175,181,182]. A cohort study consisting of 5,000 individuals found that a high intake of omega-3 fatty acids reduced the risk of PD [180].…”

Proceedings of the 5th annual symposium of the German Society for Paleo Nutrition held in 2017

“…Recent findings document a reduced risk of breast, prostate, colon and renal cancers [49]. Along with their lipid-lowering properties, omega-3 LC-PUFAs also exert cardio-protective functions, such as reducing platelet aggregation and inflammation [50,51] and controlling the presence of DHA in our body, especially in our liver and brain, which is crucial for optimal brain functionality explaining the influence on patients with major depressive and bipolar disorders [52], Alzheimer disease [53] and Parkinson's disease [54].…”

The Prevention of Alzheimer's Disease and Parkinson’s Disease by Monascus purpureus NTU 568-Fermented Compounds

“…Relevant research however, has not reached consistent conclusions, with some studies indicating that fats and fatty acids also have protective effect on neurons, and can reduce the risk of disease. Furthermore, studies have tentatively shown that estrogen and non-steroidal anti-inflammatory drugs may also have protective functions [11][12][13]. Based on the above, inhibition of oxidative stress may be an important way of alleviating and preventing PD.…”