The effects of multiple coronary artery disease risk factors on subclinical atherosclerosis in a rural population in the United States

Mamudu, Hadii M.; Paul, Timir K.; Wang, Liang; Veeranki, Sreenivas P.; Panchal, Hemang B.; Alamian, Arsham; Sarnosky, Kamrie; Budoff, Matthew J.

doi:10.1016/j.ypmed.2016.04.003

Cited by 32 publications

(30 citation statements)

References 54 publications

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“…Overall, 44% had CAC of 0, whereas the prevalence of those with mild (1–99), moderate (100–399), and severe (>400) CAC was 29%, 15%, and 11%, respectively. 13 …”

Section: Subclinical Atherosclerosismentioning

confidence: 99%

Heart Disease and Stroke Statistics—2017 Update: A Report From the American Heart Association

Benjamin¹,

Blaha²,

Chiuve³

et al. 2017

Circulation

7,606

5,040

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“…Overall, 44% had CAC of 0, whereas the prevalence of those with mild (1–99), moderate (100–399), and severe (>400) CAC was 29%, 15%, and 11%, respectively. 13 …”

Section: Subclinical Atherosclerosismentioning

confidence: 99%

Heart Disease and Stroke Statistics—2017 Update: A Report From the American Heart Association

Benjamin¹,

Blaha²,

Chiuve³

et al. 2017

Circulation

7,606

5,040

View full text Add to dashboard Cite

“…We can predict the reason of the high prevalence of multiple RFs coexistence to society growth, age profile variation, low education levels, lifestyle changes, dietary habits, lack of adoption of regular physical activity, ineffective anti-tobacco campaigns, and rise of prevalence rates of DM, metabolic syndrome, and obesity [ 28a – 28e ]. Subjects with multiple RFs were prone to higher probability developing coronary artery calcification, and premature mortality and morbidity [ 29 ]. In Jordan CVDs RFs clustering is higher than it is in other regions of the world, enhancing the potential benefits expected from aggressive preventive measures.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of cardiovascular Diseases Risk Factors Among Jordanians

Alsaud¹,

Tabbaa²,

Kasabri³

et al. 2020

Journal of the Saudi Heart Association

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Background and aims One of the most common causes of death worldwide is cardiovascular diseases (CVDs). This study evaluated the prevalence of CVDs risk factors (RFs) and their constellation electively among the Jordanian population and, assessing the most prevalent RF interplay with the rest of CVDs RFs as well as the impact of age and gender dimorphism on the frequencies of coexistence of multiple CVDs risk factors (RFs) among the Jordanian population. Methods and results In this observational multicenter study, a total of 1449 subjects were enrolled. The mean age (±SD) was 44.35 ± 14.46 years; 796 (54.9%) of them were females and 801 (55.28%) of the whole study pool had no family history of premature CVDs. Only 5.9% of the population did not have any of these RFs. The prevalence of CVDs MRFs within-affected subjects was as follows: there were 1081 (74.6%) subjects with overall dyslipidemia, 471 (32.51%) with obesity, 456 (31.47%) were smokers, and at the first diagnostic encounter 541 (37.47%) were with elevated blood pressure and, 310 (21.51%) were with elevated random blood sugar. The coexistence of ≥ two, ≥ three and, ≥ four RFs was observed in 75.7%, 44.4%, and 21.4% of the subjects, respectively. The constellation of multiple RFs was more frequent in men than that in women, where the presence of ≥ two RFs for men was at 86.18% vs. 67.09% for women. Similarly, the appearance of multiple RFs increases with age, starting from the existence of ≥ three, and four RFs respectively. Most notably the clustering of ≥ five RFs in the age group of 45–59 years showed the greatest frequency vs. any other age group. Conclusions CVDs risk factors (RFs) and clusters of them are extremely prevalent in the Jordanian population. Overall dyslipidemia is the most prevalent MRF and the most favors clustering with other CVDs RFs. Combined two RFs had the highest proportional frequency between all six RFs clusters. The constellation of at least two, three, and four CVDs RFs presented at almost three-fourth, half, and around one-fourth; respectively, Middle-aged males presented significantly higher rates of ≥ five RFs occurrences than females.

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“…Hypertension is a one of the important disease in patients with CAD [ 20 ].In the present study, patients with multimorbidity were slightly older than those without multimorbidity. Patients with several risk factors were more at risk of coronary artery disease [ 21 ].According to a recent systematic review, prevalence of multimorbidity increase in older people [ 22 ]. And also parallel with previous studies, multimorbidity was more common among women [ 3 , 23 , 24 ] and less educated people [ 25 ].…”

Section: Discussionmentioning

confidence: 99%

Effect of multimorbidity on quality of life in adult with cardiovascular disease: a cross-sectional study

Shad

Ashouri

Hasandokht

et al. 2017

Health Qual Life Outcomes

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BackgroundThe aim of present study was to describe the effect of multimorbidity on Health-Related Quality of Life (HRQoL) in patients with coronary artery disease (CAD).MethodsA cross-sectional study with a simple sampling method of 296 patients undergoing coronary artery bypass surgery in a referral hospital of the northern part of Iran was conducted between April, 2015 and September, 2016. Multimorbidity was defined as the presence of at least two chronic diseases based on self-reporting and medical records. HRQoL was measured using the 36-item short form (SF-36) health status survey. We used analysis of variance (ANOVA) to assess the effect of multimorbidity on mental and physical component of HRQoL.ResultsApproximately, 69% of CAD patients had at least one other disease like diabetes or hypertension. Patients without multimorbidity compared with patients with multimorbidity were significantly older (p = 0.012) and more educated (p = 0.002). Both physical and mental component score of HRQoL was better in patients without any morbidity (48.82 vs. 43.93 with 95%CI of mean difference: 3.37–6.42 and 54.85 vs. 50.44 with 95% CI of mean difference: 1.68–7.15, respectively). Both physical and mental component score was significantly lower in female and lower educated patients (physical mean score 43.07 vs. 46.54 with P = .001 and 42.53 vs. 46.82 with P < .001 and mental mean score 49.98 vs. 52.65 with P = .055 and 49.80 vs. 52.75 with P = .022 for sex and education, respectively). Also, two-way ANOVA showed that regards to morbidity, physical component score was grater in patients with lower education level than higher education level (P < .001).ConclusionThe findings of this study suggest that women, lower education level and overweight reported lower quality of life. HRQoL is affected by multimorbidity among CAD patients specially in less educated.

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The effects of multiple coronary artery disease risk factors on subclinical atherosclerosis in a rural population in the United States

Cited by 32 publications

References 54 publications

Heart Disease and Stroke Statistics—2017 Update: A Report From the American Heart Association

Heart Disease and Stroke Statistics—2017 Update: A Report From the American Heart Association

Prevalence of cardiovascular Diseases Risk Factors Among Jordanians

Effect of multimorbidity on quality of life in adult with cardiovascular disease: a cross-sectional study

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