1979
DOI: 10.1055/s-0028-1096239
|View full text |Cite
|
Sign up to set email alerts
|

Abstract: Fortyone of 187 infants undergoing corrective surgery for their congenital cardiac lesions using profound hypothermic circulatory arrest were randomly selected for metabolic studies. Deep hypothermia of 21 to 22 degrees C core temperature was reached by two different techniques: 1. Perfusion cooling by extracorporeal circulation (ECC-C) 2. Surface cooling with ice bags combined with perfusion cooling (SC + ECC-C) After circulatory arrest (34.2 min. ECC-C v.s. 46.7 min. SC + ECC-C) bypass rewarming was used in … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1

Citation Types

0
2
0

Year Published

1986
1986
2011
2011

Publication Types

Select...
5
2

Relationship

0
7

Authors

Journals

citations
Cited by 15 publications
(2 citation statements)
references
References 15 publications
0
2
0
Order By: Relevance
“…This previously has been described in pigs comparing aortic flush to surface cooling (17) and in infants undergoing cardiac surgery with surface and core cooling (18). Increased insulin requirements during hypothermia is understood to be attributable to a combination of decreased insulin secretion and a moderately increased insulin resistance (19), and the higher rate of hyperglycemia among surface-cooled patients might be linked to either or both of these mechanisms.…”
Section: Discussionmentioning
confidence: 89%
“…This previously has been described in pigs comparing aortic flush to surface cooling (17) and in infants undergoing cardiac surgery with surface and core cooling (18). Increased insulin requirements during hypothermia is understood to be attributable to a combination of decreased insulin secretion and a moderately increased insulin resistance (19), and the higher rate of hyperglycemia among surface-cooled patients might be linked to either or both of these mechanisms.…”
Section: Discussionmentioning
confidence: 89%
“…In our hospital in 1974 a randomized study was initiated in 41 infants, with a mean body weight of 5.64 kg, using either surface cooling or core cooling and circulatory arrest, during which the metabolic events were registered. The results were in favour of core cooling with ECC, the technique that is applied today [16]. Thus it became possible to carry out corrective surgery in children under one year of age with the diagnosis of TGA, CCAVSD, or other rare anomalies like IAA or TAPVC, anomalies which were at that time linked to a very high mortality.…”
Section: Bmentioning
confidence: 99%