The Effectiveness of 0.2% Chlorhexidine Gel on Early Wound Healing after Tooth Extraction: A Randomized Controlled Trial

Amaliya, Amaliya; Ramadhanti, Rika; Hadikrishna, Indra; Maulina, Tantry

doi:10.1055/s-0041-1739544

Cited by 9 publications

(8 citation statements)

References 40 publications

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“…20 Petersilka 17 CHX, an antibacterial agent with a high substantivity and broad antimicrobial spectrum, has been widely used in dentistry for over 40 years and is considered an excellent antiplaque agent. 22 Several methods for applying subgingival irrigation materials include using a syringe connected to a needle¹¹ , ¹³ -¹⁵ , ¹⁸ or a mechanical irrigator (WaterPik®, USA) by placing the tip about 1-2 mm into the pocket for about 7-10 min.¹² , ¹⁶ The most effective method for CHX application was demonstrated by Gottumukkala et al, 15 who used a 24-gauge needle to apply 10 ml of CHX once a week for 1 month within 20 sec.…”

Section: Discussionmentioning

confidence: 99%

Subgingival chlorhexidine irrigation for scaling and root planing adjunctive therapy in chronic periodontitis: a systematic review

2023

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BACKGROUND Scaling and root planing (SRP) is a conventional treatment for chronic periodontitis; however, it has limitations in treating deep pockets. To enhance its efficacy, chlorhexidine (CHX) is proposed as adjunctive therapy with SRP due to its broad antimicrobial spectrum, low systemic toxic activity in humans, absence of oral microorganism resistance, and lack of teratogenic effects. This study aimed to know the efficacy of the adjunctive therapy of CHX. METHODS A literature search was conducted using various databases including PubMed, LIVIVO, EBSCOhost, and Google Scholar, following the Preferred Reporting Items for Systematic Review and Meta-Analyses guidelines within the last 10 years (2011–2021). Clinical parameters such as plaque index (PI), gingival index (GI), bleeding on probing (BOP), pocket depth (PD), and clinical attachment level (CAL) were recorded. The risk of bias in the selected studies was assessed using Cochrane Collaboration’s Handbook version 5.2.0. RESULTS Of 368 studies, 10 met the inclusion criteria, with 8 of them having a higher quality. Higher reduction of PI, GI, BI, PD, and CAL were observed in SRP with CHX irrigation compared with SRP alone. CONCLUSIONS Overall, adding CHX to SRP appeared to have additional clinical benefits compared with SRP alone in the treatment of chronic periodontitis.

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Section: Discussionmentioning

confidence: 99%

Subgingival chlorhexidine irrigation for scaling and root planing adjunctive therapy in chronic periodontitis: a systematic review

2023

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“…The 1 patient in the nonlocking group was mentally handicapped, hindering the daily oral hygiene measures. 25 The other patient in the non-locking group had uncontrolled type 1 diabetes, which is thought to be the culprit of infection. 26 In spite of the fact that this was a prospective randomized study of which randomization done by lottery method, there were certain limitations; multiple mandibular fractures are one such limitation.…”

Section: Discussionmentioning

confidence: 99%

Locking Versus Non-Locking Miniplates in the Treatment of Mandibular Fractures in Above 35 Years Age Patients

Pirwani

Mirza

Tahir

et al. 2022

Ann Pak Inst Med Sci

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Objective: To compare the frequency of short term post-operative infection of locking plates versus non-locking plate in mandibular fractures in patients above 35 years of age. Methodology: A randomized controlled study was conducted at the Department of Oral and Maxillofacial Surgery, Pakistan Institute of Medical Sciences, Islamabad from January 2018 to January 2019, involving a 100 patients (50 patients in each group). On the basis of history, clinical features, orthopantomogram (OPG) and intraoperative findings, the diagnosis of mandibular fractures was established. Group A patients were treated with reduction and fixation of fracture with locking miniplates and miniscrews following champy’s principle of osteosynthesis. Whereas in group B patients, fractures were reduced and fixed with non-locking miniplates and miniscrews following champy’s principle of osteosynthesis. Results: Effect modifiers such as age, gender, and type of fracture were controlled by stratification. A post-stratification chi-square test was applied. The 1 patient that had infection in group A had an age range 50- 65 years (53 years) (P value: 0.197) while the 2 patients that had infection in group B were younger in age range of 35-50 years (36 years and 38 years) (P value: 0.322). The 1 patient who had infection in group A was female (P value: 0.043) while the 2 patients of group B who had infection were also females (P value: 0.027). In group A, only 1 patient had infection at the para-symphysis of mandible according to site (P value: 0.494). In group B, 1 patient had infection at para-symphysis of mandible and 1 at the body of the mandible site (P value: 0.599). The results were not statistically significant in terms of infection by the end of 3rd week. Conclusion: The study concludes that insignificant post-operative infection rates while managing mandibular fractures either by locking plates or non-locking plates.

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“…The flax seeds extract showed slightly more inhibitory effects against Streptococcus mutanswhen compared with fenugreek extract, showing a non-significant pvalue of 0.193. Now we can conclude that the fenugreek and flax seeds showed similar bactericidal activity when compared with conventional synthetic mouth wash. Chlorhexidine present in commercially available mouth washes have multiple reported adverse effects like dry mouth, tooth discoloration, mucosal irritation and cytotoxic effects (25) .…”

Section: Discussionmentioning

confidence: 99%

Comparison of flax seeds extract and fenugreek seed extract rinse against streptococcus mutans colonies

Zaidi¹,

Quraishi²,

Sarwath³

et al. 2022

PJMHS

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Objective: To compare flax seeds extract and fenugreek seed extractrinse against streptococcus mutans colonies Study setting: The bench work of this preclinical experimental study was carried out at Baqai Medical and Dental College Karachi., from December 2021 to January 2022. Materials and Methods: It was a preclinical experimental study. Participants were divided into 4 groups randomization was performed in allocating the groups of participants. Film of plaque from labial surface of teeth of study participants was collected on sterile strips before and after the 2 hours of intervention. The extract preparation of both the plants and culture of S. mutantcolonies were performed as per standard protocol. The extract was diluted at 1:4 for rinsing and study participants were given the rinses according to their groups. Data was analyzed by SPSS v. 22 Results: The growth of colonies was calculated on growth media plates in samples prior to rinsing and samples that were taken after the rinsing. The pre and post samples showed significant (p-value <0.05) decrease in number of colonies in positive control group (conventional rinse), flax seed extract group and fenugreek seed extract group as shown in table 1. The intra group comparison of negative and positive control showed significant difference in number of colonies and same was observed with the both the extract rinses. However, the positive control and flax seed extract and fenugreek seed extract comparison was insignificant that highlighted the equal potential of herbal extracts in reducing the streptococcus mutans colonies. Conclusion: Flax seeds extract and fenugreek seed extract mouth rinses reduced the number of colonies equally as that of commercially available mouth rinse. Keywords: Flax seed extract, Fenugreek Seed Extract, Rinse, Antibacterial, streptococcus mutans

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The Effectiveness of 0.2% Chlorhexidine Gel on Early Wound Healing after Tooth Extraction: A Randomized Controlled Trial

Cited by 9 publications

References 40 publications

Subgingival chlorhexidine irrigation for scaling and root planing adjunctive therapy in chronic periodontitis: a systematic review

Subgingival chlorhexidine irrigation for scaling and root planing adjunctive therapy in chronic periodontitis: a systematic review

Locking Versus Non-Locking Miniplates in the Treatment of Mandibular Fractures in Above 35 Years Age Patients

Comparison of flax seeds extract and fenugreek seed extract rinse against streptococcus mutans colonies

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