The effect of ventilation tube insertion on quality of life in children with persistent otitis media with effusion

Abstract

Objectives To determine the effect of ventilation tube (VT) surgery on quality of life (QoL) in children with persistent otitis media with effusion (OME). Design Secondary analysis of trial data (oral steroids versus placebo for persistent OME), comparing QoL by history of VT surgery performed between 5 weeks and 12 months post‐randomisation. Multilevel regression models were used to identify the association between VT surgery and QoL scores at 12 months, controlling for pre‐exposure risk factors associated with surgery, including pre‐surgery hearing level. Setting Ear, nose and throat (ENT), paediatric audiology and audiovestibular medicine (AVM) departments in Wales and England. Participants A total of 327 children aged 2‐8 years with OME symptoms for at least three months and audiometry‐proven bilateral hearing loss with VT surgery status. Main outcome measures Otitis Media questionnaire (OM8‐30) and Paediatric Quality of Life Inventory (PedsQL) total and subscale scores, and the Health Utilities Index Mark 3 (HUI3) at 12 months post‐randomisation. Results Participants who had VT surgery had no significant difference in OM8‐30, PedsQL or HUI total scores. OM8‐30 hearing difficulty (HD) subscale scores at 12 months were better in those who had VT surgery (adjusted mean difference (aMD) = −0.46 (95% confidence interval: −0.69 to −0.23), P < .001), and this varied by when the surgery occurred (aMD for surgery between 5 weeks and 6 months = −0.4 [−0.67 to −0.13], P = .004 and between 6 and 12 months = −0.54, [−0.87 to −0.22], P = .001). Conclusion Ventilation tube surgery was associated with an improvement in HD‐related functional health status but no change in overall QoL.

Characteristics of Hearing Recovery in Children with Chronic Otitis Media with Effusion after Ventilation Tube Insertion

“…In addition, there was no significant difference in hearing improvement between the group of children who had ventilation tubes in place for 6-9 months versus the group who had ventilation tubes in place for 10-12 months. Similar results have been reported from the study conducted by Sanyaolu et al 25 .…”

Characteristics of Hearing Recovery in Children with Chronic Otitis Media with Effusion after Ventilation Tube Insertion

“…In addition, there was no significant difference in hearing improvement between the group of children who had ventilation tubes in place for 6-9 months versus the group who had ventilation tubes in place for 10-12 months. Similar results have been reported from the study conducted by Sanyaolu et al 25 .…”

Quality of Life Outcomes After Pediatric Otitis Media Surgery: A Systematic Review and Meta‐Analysis

“…It includes 16 additional questions to further identify specific signs or symptoms related to functional health status. OM8‐30 is another alternative used by Sanyaolu 2020, and incorporates an assessment of ear infections, speech, language, and school progress, but is a lengthy survey that is difficult to score 40 . While OM‐6, OMO‐22, and OM8‐30 were rated in a 2007 review by Timmerman et al to be the best for assessing the clinical impact of disease, the OMO‐22 and OM8‐30 were highlighted to possess discriminative qualities for identifying children who may benefit from surgical intervention 41 .…”

“…OM8-30 is another alternative used by Sanyaolu 2020, and incorporates an assessment of ear infections, speech, language, and school progress, but is a lengthy survey that is difficult to score. 40 While OM-6, OMO-22, and OM8-30 were rated in a 2007 review by Timmerman et al to be the best for assessing the clinical impact of disease, the OMO-22 and OM8-30 were highlighted to possess discriminative qualities for identifying children who may benefit from surgical intervention. 41 Ultimately inclusion of studies in our meta-analysis was limited by the heterogeneity of OMI used across studies, results of which cannot be converted or generalised to a common scale.…”

Tratamento cirúrgico da otite média secretora na população infantil: uma revisão sistemática

“…As pontuações da subescala de dificuldade auditiva (HD) OM8-30 aos 12 meses foram melhores naqueles que fizeram cirurgia de TV (diferença média ajustada (aMD) = -0,46 (intervalo de confiança de 95%: -0,69 a -0,23), P < 0,001), e isso variou por quando a cirurgia ocorreu (aMD para cirurgia entre 5 semanas e 6 meses = -0,4 [-0,67 a -0,13], P = 0,004 e entre 6 e 12 meses = -0,54, [-0,87 a -0,22] , P = 0,001) (Sanyaolu LN et al 2020).…”

“…meses de sintomas e perda auditiva bilateral, sendo avaliado através da audiometria. Os parâmetros utilizaram foram HUI3, PedsQL e OM8-30(Sanyaolu LN et al 2020). …”

Characteristics of Hearing Recovery in Children with Chronic Otitis Media with Effusion after Ventilation Tube Insertion

“…In addition, there was no significant difference in hearing improvement between the group of children who had ventilation tubes in place for 6-9 months versus the group who had ventilation tubes in place for 10-12 months. Similar results have been reported from the study conducted by Sanyaolu et al 25 .…”

Quality of Life Outcomes After Pediatric Otitis Media Surgery: A Systematic Review and Meta‐Analysis

“…It includes 16 additional questions to further identify specific signs or symptoms related to functional health status. OM8‐30 is another alternative used by Sanyaolu 2020, and incorporates an assessment of ear infections, speech, language, and school progress, but is a lengthy survey that is difficult to score 40 . While OM‐6, OMO‐22, and OM8‐30 were rated in a 2007 review by Timmerman et al to be the best for assessing the clinical impact of disease, the OMO‐22 and OM8‐30 were highlighted to possess discriminative qualities for identifying children who may benefit from surgical intervention 41 .…”

“…OM8-30 is another alternative used by Sanyaolu 2020, and incorporates an assessment of ear infections, speech, language, and school progress, but is a lengthy survey that is difficult to score. 40 While OM-6, OMO-22, and OM8-30 were rated in a 2007 review by Timmerman et al to be the best for assessing the clinical impact of disease, the OMO-22 and OM8-30 were highlighted to possess discriminative qualities for identifying children who may benefit from surgical intervention. 41 Ultimately inclusion of studies in our meta-analysis was limited by the heterogeneity of OMI used across studies, results of which cannot be converted or generalised to a common scale.…”

Tratamento cirúrgico da otite média secretora na população infantil: uma revisão sistemática

“…As pontuações da subescala de dificuldade auditiva (HD) OM8-30 aos 12 meses foram melhores naqueles que fizeram cirurgia de TV (diferença média ajustada (aMD) = -0,46 (intervalo de confiança de 95%: -0,69 a -0,23), P < 0,001), e isso variou por quando a cirurgia ocorreu (aMD para cirurgia entre 5 semanas e 6 meses = -0,4 [-0,67 a -0,13], P = 0,004 e entre 6 e 12 meses = -0,54, [-0,87 a -0,22] , P = 0,001) (Sanyaolu LN et al 2020).…”

“…meses de sintomas e perda auditiva bilateral, sendo avaliado através da audiometria. Os parâmetros utilizaram foram HUI3, PedsQL e OM8-30(Sanyaolu LN et al 2020). …”

Characteristics of Hearing Recovery in Children with Chronic Otitis Media with Effusion after Ventilation Tube Insertion

“…In addition, there was no significant difference in hearing improvement between the group of children who had ventilation tubes in place for 6-9 months versus the group who had ventilation tubes in place for 10-12 months. Similar results have been reported from the study conducted by Sanyaolu et al 25 .…”

Quality of Life Outcomes After Pediatric Otitis Media Surgery: A Systematic Review and Meta‐Analysis

“…It includes 16 additional questions to further identify specific signs or symptoms related to functional health status. OM8‐30 is another alternative used by Sanyaolu 2020, and incorporates an assessment of ear infections, speech, language, and school progress, but is a lengthy survey that is difficult to score 40 . While OM‐6, OMO‐22, and OM8‐30 were rated in a 2007 review by Timmerman et al to be the best for assessing the clinical impact of disease, the OMO‐22 and OM8‐30 were highlighted to possess discriminative qualities for identifying children who may benefit from surgical intervention 41 .…”

“…OM8-30 is another alternative used by Sanyaolu 2020, and incorporates an assessment of ear infections, speech, language, and school progress, but is a lengthy survey that is difficult to score. 40 While OM-6, OMO-22, and OM8-30 were rated in a 2007 review by Timmerman et al to be the best for assessing the clinical impact of disease, the OMO-22 and OM8-30 were highlighted to possess discriminative qualities for identifying children who may benefit from surgical intervention. 41 Ultimately inclusion of studies in our meta-analysis was limited by the heterogeneity of OMI used across studies, results of which cannot be converted or generalised to a common scale.…”

Tratamento cirúrgico da otite média secretora na população infantil: uma revisão sistemática

“…As pontuações da subescala de dificuldade auditiva (HD) OM8-30 aos 12 meses foram melhores naqueles que fizeram cirurgia de TV (diferença média ajustada (aMD) = -0,46 (intervalo de confiança de 95%: -0,69 a -0,23), P < 0,001), e isso variou por quando a cirurgia ocorreu (aMD para cirurgia entre 5 semanas e 6 meses = -0,4 [-0,67 a -0,13], P = 0,004 e entre 6 e 12 meses = -0,54, [-0,87 a -0,22] , P = 0,001) (Sanyaolu LN et al 2020).…”

“…meses de sintomas e perda auditiva bilateral, sendo avaliado através da audiometria. Os parâmetros utilizaram foram HUI3, PedsQL e OM8-30(Sanyaolu LN et al 2020). …”