1986
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The effect of thioacetamide on rat liver plasma membrane enzymes and its potentiation by fasting
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Cited by 7 publications
(3 citation statements)
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Abstract
Smart CitationsHow this paper cites the one you are viewing
“…TB, bromobenzene, Lawesson's reagent, and methyl benzimidate hydrochloride were purchased from Aldrich (Milwaukee, WI). Benzoic acid-d 5 solution in 10% H 3 PO 4 followed by heating. Radioactivity on the TLC plate was detected by exposing it to a Molecular Dynamics phosphor screen (3 days at room temperature) and scanning the screen with a Bio-Rad Molecular Imager FX scanning unit.…”
Section: Methods
mentioning
confidence: 99%
“…For example, thiourea (TU), phenylthiourea, and α-naphthylthiourea (ANTU) have long been known for their acute pneumotoxicity to rats, and ANTU was once widely used as a rodenticide ( , ). In contrast to the pneumotoxic TUs, thioamide derivatives such as thioacetamide (TA) ( − ) and thiobenzamide (TB, 1 ) ( − ) are hepatotoxic in rats. Both cause centrilobular necrosis along with profound hyperbilirubinemia.…”
Section: Introduction
mentioning
confidence: 99%
Abstract
Smart CitationsHow this paper cites the one you are viewing
“…TB, bromobenzene, Lawesson's reagent, and methyl benzimidate hydrochloride were purchased from Aldrich (Milwaukee, WI). Benzoic acid-d 5 solution in 10% H 3 PO 4 followed by heating. Radioactivity on the TLC plate was detected by exposing it to a Molecular Dynamics phosphor screen (3 days at room temperature) and scanning the screen with a Bio-Rad Molecular Imager FX scanning unit.…”
Section: Methods
mentioning
confidence: 99%
“…For example, thiourea (TU), phenylthiourea, and α-naphthylthiourea (ANTU) have long been known for their acute pneumotoxicity to rats, and ANTU was once widely used as a rodenticide ( , ). In contrast to the pneumotoxic TUs, thioamide derivatives such as thioacetamide (TA) ( − ) and thiobenzamide (TB, 1 ) ( − ) are hepatotoxic in rats. Both cause centrilobular necrosis along with profound hyperbilirubinemia.…”
Section: Introduction
mentioning
confidence: 99%
Abstract
Smart CitationsHow this paper cites the one you are viewing
“…Η αύξησή της μετά από 12 εβδομάδες από την χορήγηση ΤΑΑ θα πρέπει να διερευνηθεί περαιτέρω ούτως ώστε να συσχετισθεί με τον σημαντικό βαθμό ίνωσης του ήπατος. Όπως αναφέρεται από τουςNikolaev et al, 1986 και De Ferreyra et al, 1983, η ΤΑΑ προκαλεί νέκρωση μέσω εκλεκτικής βλάβης στην πλασματική μεμβράνη των ηπατικών κυττάρων. Ο CCl 4 απάγει ένα άτομο υδρογόνου από τα ακόρεστα λιπίδια τη ς πλασματικής μεμβράνης, προκαλώντας λιπιδική υπεροξείδωση(Tsukamoto et al, 1990).…”
unclassified
Abstract
Smart CitationsHow this paper cites the one you are viewing
“…TB, bromobenzene, Lawesson's reagent, and methyl benzimidate hydrochloride were purchased from Aldrich (Milwaukee, WI). Benzoic acid-d 5 solution in 10% H 3 PO 4 followed by heating. Radioactivity on the TLC plate was detected by exposing it to a Molecular Dynamics phosphor screen (3 days at room temperature) and scanning the screen with a Bio-Rad Molecular Imager FX scanning unit.…”
Section: Methods
mentioning
confidence: 99%
“…For example, thiourea (TU), phenylthiourea, and α-naphthylthiourea (ANTU) have long been known for their acute pneumotoxicity to rats, and ANTU was once widely used as a rodenticide ( , ). In contrast to the pneumotoxic TUs, thioamide derivatives such as thioacetamide (TA) ( − ) and thiobenzamide (TB, 1 ) ( − ) are hepatotoxic in rats. Both cause centrilobular necrosis along with profound hyperbilirubinemia.…”
Section: Introduction
mentioning
confidence: 99%
Abstract
Smart CitationsHow this paper cites the one you are viewing
“…Η αύξησή της μετά από 12 εβδομάδες από την χορήγηση ΤΑΑ θα πρέπει να διερευνηθεί περαιτέρω ούτως ώστε να συσχετισθεί με τον σημαντικό βαθμό ίνωσης του ήπατος. Όπως αναφέρεται από τουςNikolaev et al, 1986 και De Ferreyra et al, 1983, η ΤΑΑ προκαλεί νέκρωση μέσω εκλεκτικής βλάβης στην πλασματική μεμβράνη των ηπατικών κυττάρων. Ο CCl 4 απάγει ένα άτομο υδρογόνου από τα ακόρεστα λιπίδια τη ς πλασματικής μεμβράνης, προκαλώντας λιπιδική υπεροξείδωση(Tsukamoto et al, 1990).…”
unclassified
Abstract
Smart CitationsHow this paper cites the one you are viewing
“…TB, bromobenzene, Lawesson's reagent, and methyl benzimidate hydrochloride were purchased from Aldrich (Milwaukee, WI). Benzoic acid-d 5 solution in 10% H 3 PO 4 followed by heating. Radioactivity on the TLC plate was detected by exposing it to a Molecular Dynamics phosphor screen (3 days at room temperature) and scanning the screen with a Bio-Rad Molecular Imager FX scanning unit.…”
Section: Methods
mentioning
confidence: 99%
“…For example, thiourea (TU), phenylthiourea, and α-naphthylthiourea (ANTU) have long been known for their acute pneumotoxicity to rats, and ANTU was once widely used as a rodenticide ( , ). In contrast to the pneumotoxic TUs, thioamide derivatives such as thioacetamide (TA) ( − ) and thiobenzamide (TB, 1 ) ( − ) are hepatotoxic in rats. Both cause centrilobular necrosis along with profound hyperbilirubinemia.…”
Section: Introduction
mentioning
confidence: 99%
Abstract
Smart CitationsHow this paper cites the one you are viewing
“…Η αύξησή της μετά από 12 εβδομάδες από την χορήγηση ΤΑΑ θα πρέπει να διερευνηθεί περαιτέρω ούτως ώστε να συσχετισθεί με τον σημαντικό βαθμό ίνωσης του ήπατος. Όπως αναφέρεται από τουςNikolaev et al, 1986 και De Ferreyra et al, 1983, η ΤΑΑ προκαλεί νέκρωση μέσω εκλεκτικής βλάβης στην πλασματική μεμβράνη των ηπατικών κυττάρων. Ο CCl 4 απάγει ένα άτομο υδρογόνου από τα ακόρεστα λιπίδια τη ς πλασματικής μεμβράνης, προκαλώντας λιπιδική υπεροξείδωση(Tsukamoto et al, 1990).…”
unclassified