The Effect of Smartphone's Radiation Frequency and Exposure Duration on NADPH Oxidase 5 (NOX5) Level in Sperm Parameters

Jamaludin, Norazurashima; Razak, Syawal Shafie Abdul; Jaffar, Farah Hanan Fathihah; Osman, Khairul; Ibrahim, Siti Fatimah

doi:10.17576/jsm-2017-4609-31

Cited by 6 publications

(5 citation statements)

References 16 publications

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“…The integrity of sperm DNA was assessed by performing the Comet assay with some modifications [13]. Frosted slides (StatLab Medical Product Inc., Texas) were covered with 200 µL of 1 % (w/v) normal melting agar (NMA) and coverslips were placed promptly to allow it to solidify at 4 °C for 10 min.…”

Section: Quantitative Assessment Of Dna Damage (Comet Assay)mentioning

confidence: 99%

Thymoquinone enhances sperm DNA integrity in nicotineinduced infertile male rats

Rosli¹,

Hashim²,

Mohd-Yusuf³

et al. 2021

Trop. J. Pharm Res

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Purpose: To assess the effects of thymoquinone (TQ) on the integrity of sperm DNA in nicotineinduced sperm impairment in rats. Methods: Adult male Sprague Dawley rats were randomized into four equal groups: control group received normal saline orally for 60 days; nicotine group was subcutaneously injected with 5 mg/kg/day nicotine for 30 days and then given normal saline for the next 30 days; TQ group was given normal saline for 30 days followed by TQ at 5 mg/kg/day for 30 days; and nicotine-TQ group received 5 mg/kg of nicotine for 30 days and 5mg/kg of TQ for another 30 days. Sperm DNA breakages were evaluated using Comet assay. The expression levels of protamine 1 (PT1) and transition nuclear protein 2 (Tnp2) genes which are essential for the proper compaction of the sperm DNA were analyzed by quantitative polymerase chain reaction (qPCR). Results: Thymoquinone significantly decreased DNA fragmentation in the sperm of nicotine-treated rats. However, there was no change in PT1 gene expression. Tnp2 was downregulated in the nicotine group and slightly upregulated in nicotine-TQ group (p < 0.05). Conclusion: The results demonstrate the potential benefits of TQ in improving sperm DNA quality of nicotine-induced male infertility.

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Section: Quantitative Assessment Of Dna Damage (Comet Assay)mentioning

confidence: 99%

Thymoquinone enhances sperm DNA integrity in nicotineinduced infertile male rats

Rosli¹,

Hashim²,

Mohd-Yusuf³

et al. 2021

Trop. J. Pharm Res

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“…Many organic materials have been effectively used to produce VC, including animal manures [16,18], sewage sludge [15,19], paper pulp [13,14], and coffee grounds [20][21][22]. The addition of VC produced from these different substrates has similarly improved plant growth and yield among a broad spectrum of plant species and cultivars.…”

Section: Introductionmentioning

confidence: 99%

“…6(4).2020 to be altered depending on the materials utilized [13][14][15]17,19]. Although coffee as a substrate to produce VC has been evaluated in several studies [20][21][22], there is still limited information available regarding the influences on plant growth and yield, particularly for greenhouse crops such as spinach, lettuce and other fast growing salad greens. Moreover, CVC is also high in N (3.2% to 3.6%) [21,22], soluble P, Ca and Mg [22], which are oftentimes some of the nutrients most limiting for crop production.…”

Section: Introductionmentioning

confidence: 99%

“…Although coffee as a substrate to produce VC has been evaluated in several studies [20][21][22], there is still limited information available regarding the influences on plant growth and yield, particularly for greenhouse crops such as spinach, lettuce and other fast growing salad greens. Moreover, CVC is also high in N (3.2% to 3.6%) [21,22], soluble P, Ca and Mg [22], which are oftentimes some of the nutrients most limiting for crop production. In addition to improving plant growth and yield, VC has been found to increase the ascorbic acid (AA) content of some fruits and vegetables, such as tomatoes [23], strawberries [24], and lettuce [25].…”

Section: Introductionmentioning

confidence: 99%

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Impact of Vermicompost Fertilizer on Spinach Yield and Nutritional Components

Walters

2020

MCDA

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Alternative fertilization practices, such the use of vermicompost (VC), have shown great potential to improve both the physical and biological attributes of soils and supplement the nutrient status of soils to improve fertility for vegetable crop production. Modification of soils with coffee vermicompost (CVC) has the potential to improve soil organic content, structure, and microbial activity. Generally, organic fertilizers with slow release nutrient capabilities efficiently use nitrogen and reduce nitrate levels in leafy green vegetables and have been shown to increase ascorbic acid (AA) content. A greenhouse study was conducted over two growing seasons (2011 and 2012) to assess the influence of four CVC rates (0, 25%, 50%, and 75% v/v of soil mix) on Spinacia oleracea growth parameters including fresh leaf weight, leaf area, plant height, leaf number, fresh leaf ascorbic acid (AA) and dry leaf nitrate (DLN). Spinach leaf number and fresh leaf weight increased with CVC rate for both growing seasons and were best described by increasing linear relationships. Surprisingly, spinach AA content remained the same whether DLN content was high or low; and AA and nitrate content were both at highest levels with the 75% v/v CVC treatment in both years. These results indicated that applications of an alternative fertilizer such as CVC can improve spinach yield and that AA content does not always decrease with higher VC application rates, even as nitrate content increases.

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“…The RF-EMR emitted from Wi-Fi transmitter involves whole body exposure (Wu et al 2010;Banaceur et al 2013) while mobile phone involves localized RF-EMR exposure (Ozorak et al 2013;Grell et al 2016;Jamaludin et al 2017). RF-EMR is classified as non-ionizing radiation and theoretically is unable to induce ionization of cellular atoms and molecules.…”

Section: Introductionmentioning

confidence: 99%

Adverse Effects of Wi-Fi Radiation on Male Reproductive System: A Systematic Review

Jaffar

Osman

Ismail

et al. 2019

Tohoku J. Exp. Med.

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Extensive use of Wi-Fi has contributed to radiofrequency electromagnetic radiation (RF-EMR) pollution in environment. Various studies have been conducted to evaluate the effect of RF-EMR emitted by Wi-Fi transmitter on male reproduction health. However, there are conflicting findings between studies. Thus, this review aims to elucidate the possible effects of 2.45 GHz Wi-Fi exposure on both animal and human male reproductive system. A computerized database search performed through MEDLINE via Ovid and PUBMED with the following set of keywords: 'Wi-Fi or WiFi or wireless fidelity or Wi-Fi router or WiFi router or electromagnetic or radiofrequency radiation' AND 'sperm or spermatozoa or spermatogenesis or semen or seminal plasma or testes or testis or testosterone or male reproduction' had returned 526 articles. Only 17 studies conformed to pre-set inclusion criterion. Additional records identified through Google Scholar and reviewed article further revealed six eligible articles. A total of 23 articles were used for data extraction, including 15 studies on rats, three studies on mice, and five studies on human health. Sperm count, motility and DNA integrity were the most affected parameters when exposed to RF-EMR emitted by Wi-Fi transmitter. Unfortunately, sperm viability and morphology were inconclusive. Structural and/or physiological analyses of the testes showed degenerative changes, reduced testosterone level, increased apoptotic cells, and DNA damage. These effects were mainly due to the elevation of testicular temperature and oxidative stress activity. In conclusion, exposure towards 2.45 GHz RF-EMR emitted by Wi-Fi transmitter is hazardous on the male reproductive system.

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The Effect of Smartphone's Radiation Frequency and Exposure Duration on NADPH Oxidase 5 (NOX5) Level in Sperm Parameters

Abstract: Health hazard through smart phone radiation has been associated with male infertility. The suspected prime mediator is the NOX5 enzyme. When activated, the additional pathway for free radical production will damage sperm's DNA. However RF-EMW.

Cited by 6 publications

References 16 publications

Thymoquinone enhances sperm DNA integrity in nicotineinduced infertile male rats

Thymoquinone enhances sperm DNA integrity in nicotineinduced infertile male rats

Impact of Vermicompost Fertilizer on Spinach Yield and Nutritional Components

Adverse Effects of Wi-Fi Radiation on Male Reproductive System: A Systematic Review

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