The effect of psychotherapy on anxiety, depression, and quality of life in patients with diabetic retinopathy

Abstract

Background: Diabetic retinopathy (DR) is one of the common microvascular complications in diabetic patients, which is characterized by progressive development and often leads to irreversible visual impairment. More seriously, DR patients suffer great psychological stress due to impaired visual function and reduced self-care ability such as anxiety and depression, which seriously affect the quality of life of patients. In recent years, various psychological therapies have been applied to alleviate anxiety, depression, and quality of life in DR patients, which have achieved positive results. However, the effectiveness and safety of different psychological therapies are unclear. This study aims to assess the effects of psychotherapy on anxiety, depression, and quality of life in DR patients through a network meta-analysis. Methods: All randomized controlled trials (RCTs) on the effects of psychotherapy on anxiety, depression, and quality of life in patients with DR published before 30 November 30, 2021, will be searched in the PubMed, EMBASE, Cochrane Register of Controlled Trials, Web of Science, Chinese Scientific Journal Database, China National Knowledge Infrastructure Database, Wanfang, and China Biomedical Literature Database. There will have no restrictions on publication status and language. Two researchers will be independently responsible for RCT screening, data extraction, and quality evaluation. All statistical analyses will be performed using Stata 14.0 and R 4.1.2. Results: The results of this meta-analysis will be submitted to a peer-reviewed journal for publication. Conclusion: This study will provide comprehensive and reliable evidence-based references for elucidating the efficacy of psychotherapy on anxiety, depression, and quality of life in DR patients. Ethics and dissemination: Ethical approval was not required for this study. The systematic review will be published in a peer-reviewed journal, presented at conferences, and shared on social media platforms. OSF Registration number: DOI 10.17605/OSF.IO/K8T27.

Patient-centered perspectives in diabetic retinopathy care: phenomenology and practice

“…The patients experienced challenging emotional reactions and lacked adequate coping mechanisms throughout the presurgery phase. They grew more unsure as the healing process progressed 3. They decided to change since they lacked confidence during the discharge preparation stage.…”

Effectiveness and safety of traditional Chinese medicine for diabetic retinopathy: A systematic review and network meta-analysis of randomized clinical trials

“…To the best of our knowledge, this study is the first NMA focused on the combination of OCM with conventional Western medicine for the treatment of DR, and is the NMA with the largest number of original studies included, the largest number of subjects, and the largest variety of OCM included to date. Only five NMAs[ 123 - 127 ] have reported the therapeutic effect on DR, and only one[ 125 ] of them is about the efficacy of herbal injections for DR. This study comprehensively collected RCTs involving 9 commonly used OCMs in China and included 6 clinical indicators commonly used to evaluate the efficacy of DR, the largest number of included indicators we are aware of to date in a similar report.…”

Association between dry eye disease and depression: An umbrella review

“…Fourth, further studies should summarize the evidence on the association between the severity of dry eye disease and that of depression. Fifth, we only explored the association between dry eye and depression, however, we acknowledged that the association between other eye disease or their treatments [such as retinopathy ( 62 , 63 ), cataract surgery ( 64 ), and glaucoma ( 65 , 66 )] and depression has already been proved in previously published meta-analysis. Finally, the high-quality meta-analysis investigating the association between dry eye disease and depression are lacking currently.…”