The Effect of Probiotic Yogurt Containing Lactobacillus Acidophilus LA-5 and Bifidobacterium Lactis BB-12 on Selected Anthropometric Parameters in Obese Individuals on an Energy-Restricted Diet: A Randomized, Controlled Trial

Abstract

Previous studies using probiotics have shown strain-dependent effects on body mass index (BMI), body mass, or fat mass (FM). The aim of this study was to evaluate how the addition of yogurt containing Lactobacillus acidophilus LA-5 and Bifidobacterium animalis subsp. lactis BB-12 strains to a diet plan affects selected anthropometric parameters in obese people on an energy-restricted diet. Fifty-four subjects aged 20–49 (34.52 ± 9.58) years were included in this study. The recruited subjects were assigned to two subgroups: consuming probiotic yogurt along with a hypocaloric diet (GP) (n–27) or the same diet but without an intentional introduction of yogurt (GRD) (n–27) for 12 weeks. Both GP and GRD decreased body weight, BMI, fat mass and visceral fat by 5.59 kg and 4.71 kg, 1.89 and 1.61 kg/m2, 4.80 kg and 4.07 kg, and 0.68 and 0.65 L, respectively, although the obtained differences were not significant. Analysis of GP and GRD results separately at the beginning and end of the intervention showed that fat loss was substantial in both groups (p < 0.05). Consumption of yogurt containing LA-5 and BB-12 does not significantly improve anthropometric parameters in obese patients.

Microbiome-Targeted Therapies as an Adjunct to Traditional Weight Loss Interventions: A Systematic Review and Meta-Analysis

“… Synbiotics Eslamparast 2014 38 Iran Randomized, double-blind, placebo-controlled pilot study 28 weeks 38 adults with metabolic syndrome; Age: 46.8 ± 9.5 years; BMI: 31.8 ± 2.5 kg/m 2 ; 60.5% female; Attrition: 0% Probiotic : Capsule containing 2×10 8 CFU of seven strains ( Lactobacillus casei, Lactobacillus rhamnosus, Streptococcus thermophilus, Bifidobacterium breve, Lactobacillus acidophilus, Bifidobacterium longum and Lactobacillus bulgaricus ) Prebiotic : 250mg FOS Hypocaloric diet (500–1000 kcal reduction) + 20–30 min of high-intensity exercise 3–4 day/week (or more) A) Synbiotic capsule + diet + exercise (n=19) B) Placebo capsule + diet + exercise (n=19) NS within- or between-group differences in BMI and WC. Eslamparast 2014b 39 Iran Randomized, double-blind, placebo-controlled pilot study 28 weeks 52 adults with non-alcoholic fatty liver disease; Age: 46.0 ± 9.2 years; BMI: 31.7 ± 2.4 kg/m 2 ; 92.6% female; Attrition: 7.7% Probiotic : Capsule containing 2×10 8 CFU of seven strains ( Lactobacillus casei, Lactobacillus rhamnosus, Streptococcus thermophilus, Bifidobacterium breve, Lactobacillus acidophilus, Bifidobacterium longum and Lactobacillus bulgaricus ) Prebiotic : 250mg FOS Hypocaloric diet (500–1000 kcal reduction) + 20–30 min of high-intensity exercise 3–4 day/week (or more) A) Synbiotic capsule + diet + exercise (n=26) B) Placebo capsule + diet + exercise (n=26) Reduced *BMI and *WHR in both groups, but NS differences between groups. Ferolla 2016 66 Brazil Randomized, controlled, single-blind study 3 months 50 adults with non-alcoholic fatty liver disease; Age: median=57.3 years BMI: 32.5 ± 4.0 kg/m 2 ; 76% female; Attrition: 0% Probiotic : 2 capsules of Lactobacillus reuteri (1 x 10 8 CFU) Prebiotic : 4g partially hydrolyzed guar gum and inulin Hypocaloric diet (1500/1800 kcal for women/men – a 500–1000 kcal reduction) A) Synbiotic capsule + diet (n=27) B) Placebo capsule + diet (n=23) ...…”

Changes in Novel Anthropometric Indices of Abdominal Obesity during Weight Loss with Selected Obesity-Associated Single-Nucleotide Polymorphisms: A Small One-Year Pilot Study

“…The study was conducted according to the guidelines of the Declaration of Helsinki and approved by the Ethics Committee of the Medical University of Lublin (decision number: KE-0254/180/2019). The details of the test group, weight loss intervention, and outcome measurements have been described in our previous papers [ 38 , 39 ].…”

The Long-Term Dietitian and Psychological Support of Obese Patients Who Have Reduced Their Weight Allows Them to Maintain the Effects

“…In this phase, special attention was paid to personalization of the nutritional plan and an individual approach to the patient. The details of the intervention have been described in our previous paper [41]. Briefly, a nutrition interview was conducted, and five-day food diaries prepared by the participants were analyzed to compose a personal diet for each patient.…”

“…using sealed envelopes. The details of the exclusion and inclusion criteria (based mainly on AACE/ACE classification [48]) have been described in our previous paper [41]. The study was conducted in accordance with the Declaration of Helsinki, and the Ethics Committee of the Medical University of Lublin approved the protocol.…”

“…Moreover, body composition analysis was performed in the SG group in Ph1 every month. Anthropometric analyses were carried out according to the method described previously by Banach et al [41]. Briefly, besides body height, mass and the WC, a SECA mBCA515 (seca GmbH & Co.…”