The effect of newly initiated exercise training on dynamic thiol / disulphide homeostasis in sedentary obese adults

Çelik, Hakim; Kilic, Tugba; Kaplan, Davut Sinan; Eren, Mehmet Ali; Erel, Özcan; Karakılçık, Ali Ziya; Bağcı, Cahit

doi:10.1590/0001-3765201920180930

Cited by 5 publications

(3 citation statements)

References 31 publications

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“…Nonetheless, the contrasting results of the literature can be explained by different antioxidant nutritional status or by different intensity, duration and frequency of the training, type of the exercise (Finaud et al, 2006), previous training experience, inclusion of an untrained control group, number of participants, as well as anthropometric parameters such as body mass index (BMI), age, and sex (Celik et al, 2019). It is possible that sex may influence the degree of oxidative stress; women can be less susceptible to oxidative stress than men considering the antioxidant properties of estrogens, especially during periods when estrogens levels are high (e.g., ovulation) (Bloomer et al, 2009).…”

Section: Aerobic Exercise and Oxidative Stressmentioning

confidence: 99%

“…It is possible that sex may influence the degree of oxidative stress; women can be less susceptible to oxidative stress than men considering the antioxidant properties of estrogens, especially during periods when estrogens levels are high (e.g., ovulation) (Bloomer et al, 2009). Nevertheless, only few studies regarding the aerobic exercise-related oxidative stress, in healthy human, evaluated and found differences among sexes in oxidative stress biomarkers (Bloomer and Fisher-Wellman, 2008;Kabasakalis et al, 2014;Souglis et al, 2018;Celik et al, 2019).…”

Section: Aerobic Exercise and Oxidative Stressmentioning

confidence: 99%

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Exercise-Related Oxidative Stress as Mechanism to Fight Physical Dysfunction in Neuromuscular Disorders

et al. 2020

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Neuromuscular diseases (NMDs) are a group of often severely disabling disorders characterized by dysfunction in one of the main constituents of the motor unit, the cardinal anatomic-functional structure behind force and movement production. Irrespective of the different pathogenic mechanisms specifically underlying these disease conditions genetically determined or acquired, and the related molecular pathways involved in doing that, oxidative stress has often been shown to play a relevant role within the chain of events that induce or at least modulate the clinical manifestations of these disorders. Due to such a putative relevance of the imbalance of redox status occurring in contractile machinery and/or its neural drive in NMDs, physical exercise appears as one of the most important conditions able to positively interfere along an ideal axis, going from a deranged metabolic cell homeostasis in motor unit components to the reduced motor performance profile exhibited by the patient in everyday life. If so, it comes out that it would be important to identify a proper training program, suitable for load and type of exercise that is able to improve motor performance in adaptation and response to such a homeostatic imbalance. This review therefore analyzes the role of different exercise trainings on oxidative stress mechanisms, both in healthy and in NMDs, also including preclinical studies, to elucidate at which extent these can be useful to counteract muscle impairment associated to the disease, with the final aim of improving physical functions and quality of life of NMD patients.

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Section: Aerobic Exercise and Oxidative Stressmentioning

confidence: 99%

Section: Aerobic Exercise and Oxidative Stressmentioning

confidence: 99%

Exercise-Related Oxidative Stress as Mechanism to Fight Physical Dysfunction in Neuromuscular Disorders

et al. 2020

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“…Thiol disulfide homeostasis is accepted as the most current oxidative stress marker in the literature. Dynamic thiol disulfide homeostasis has been investigated in many conditions thought to be associated with oxidative stress Celik et al (2019a), Kayacan et al (2019b). In a study investigating the redox status and…”

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confidence: 99%

The Bidirectional Effect of Creatine Supports the Maintenance of Oxidant-Antioxidant Homeostasis During Exercise

Taskin

Çelik

Demiryürek

et al. 2021

Int. J. Res. Granthaalayah

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The importance of supplements used with exercise is increasing day by day. In this study, it was aimed to evaluate the effects of creatine monohydrate (CrM) supplementation with different intensities of exercise on oxidative stress through dynamic thiol disulfide homeostasis. Fourty two BALB/c mice were used and randomly divided into 6 groups; control (C), low-intensity exercise (LIE), high-intensity exercise (HIE), C+CrM (4% of daily diet), LIE+CrM, and HIE+CrM groups. Exercise groups were performed low-intensity (8m/min/30min/day) and high-intensity (24m/min/30min/day) exercise on a mouse treadmill for 8 weeks. At the end of the experimental period, the thiol disulfide homeostasis levels analyzed by using a new automated measurement technique. When the native thiol and total thiol values were examined the difference between the groups was statistically significant (respectively, p=0.029, p=0,035). Creatine intake with exercise decreased native thiol and total thiol levels. However, serum disulfide levels were lower in LIE+CrM compared to other study groups, but there was no statistically significant difference. It is thought that creatine supplementation with exercise reduces the thiol-disulfide homeostasis burden of the organism, and that after the depletion of creatine stores, the sustainability of oxidant-antioxidant homeostasis can be extended, thus prolonging the duration of antioxidant resistance.

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Thiol/disulfide homeostasis in patients treated with normobaric or hyperbaric oxygen for carbon monoxide poisoning

Işler

Kaya

2022

The American Journal of Emergency Medicine

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The effect of newly initiated exercise training on dynamic thiol / disulphide homeostasis in sedentary obese adults

Abstract: The effect of newly initiated exercise training on dynamic thiol / disulphide homeostasis in sedentary obese adults. An Acad Bras Cienc 91: e20180930.

Cited by 5 publications

References 31 publications

Exercise-Related Oxidative Stress as Mechanism to Fight Physical Dysfunction in Neuromuscular Disorders

Exercise-Related Oxidative Stress as Mechanism to Fight Physical Dysfunction in Neuromuscular Disorders

The Bidirectional Effect of Creatine Supports the Maintenance of Oxidant-Antioxidant Homeostasis During Exercise

Thiol/disulfide homeostasis in patients treated with normobaric or hyperbaric oxygen for carbon monoxide poisoning

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