The effect of mivacurium pretreatment on intra‐ocular pressure changes induced by suxamethonium

Abstract

SummaryWe have evaluated the effects of the volume and speed of administration of local anaesthetic during peribulbar anaesthesia. One hundred and forty patients scheduled for cataract surgery were randomly allocated to one of four groups of 35. Each patient received an injection of the same mixture of lignocaine, bupivacaine and hyaluronidase. Patients in group A were given 9 ml at a speed of 5 ml.min À1 , group B were given the same volume at 12 ml.min À1 , group C were given 13.5 ml at 5 ml.min À1 and group D were given 13.5 ml at 12 ml.min À1 . A significantly higher incidence of satisfactory akinesia was found in group D, whose pain score at injection was no higher than for the other groups. Large volumes of local anaesthetic significantly affected intraocular pressure. The incidences of early and late ptosis or diplopia were not affected by either the rate of injection or the volume of local anaesthetic.

Effects of robot-assisted laparoscopic radical prostatectomy on normal and glaucomatous eyes

“…The inference is that a decrease in systemic circulatory dynamics results in a decrease in aqueous humor production. Induction of anesthesia reportedly decreases IOP by 5-7 mmHg (20-40%) when compared with IOP prior to the induction of anesthesia [11][12][13][14] . The results of our study were also similar to the ndings of these reports.…”

Suxamethonium and intra‐ocular pressure

“…Chiu and colleagues reported that pretreatment with mivacurium prevented the increase in intra‐ocular pressure associated with the administration of suxamethonium [1]. Using a rapid‐sequence induction technique with alfentanil and propofol, the mean increase in intra‐ocular pressure was 0.4 mmHg in the mivacurium group versus 3.5 mmHg in the control group.…”