The effect of long term under- and over-feeding on milk and plasma fatty acids profile and on insulin and leptin concentrations of goats

Tsiplakou, Eleni; Chadio, Stella; Papadomichelakis, George; Zervas, G.

doi:10.1016/j.idairyj.2011.05.010

Cited by 23 publications

(34 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Before male introduction, the NEFA concentrations of the HHl-Mel and HHl+Mel does were higher than in their corresponding comparison groups before male introduction. This agrees with that reported by Tsiplakou et al (2012) and Gallego-Calvo et al (2015b), who suggest that NEFAs are the link between energy balance and reproduction.…”

Section: Discussionsupporting

confidence: 93%

“…Our group recently reported that animals increasing their body weight/body fat reserves, like those of the present LLg group, showed higher plasma insulin and glucose concentrations, and that this might explain these animals' improved reproductive results (Gallego-Calvo et al, 2015b). Insulin concentrations were not monitored in the present study since the results were so clear in this earlier work, and because the literature clearly shows that plasma insulin concentrations increase, and better reproductive results are achieved, in does fed large amounts of concentrate (Todini et al, 2007) or when they are overfed (Tsiplakou et al, 2012). The second possible explanation lies in the fact that plasma IGF-1 concentrations became higher in the LLg+Mel, LLgMel and HHl+Mel subgroups compared to the HHl-Mel subgroup.…”

Section: Discussionmentioning

confidence: 49%

See 1 more Smart Citation

The reproductive performance of female goats treated with melatonin is not improved after introduction to bucks displaying springtime sexual activity if these does are experiencing decreasing body weight/condition score

Zarazaga

Gatica

Gallego-Calvo

et al. 2017

Animal Reproduction Science

View full text Add to dashboard Cite

Title: The reproductive performance of female goats treated with melatonin is not improved after introduction to bucks displaying springtime sexual activity if these does are experiencing decreasing body weight/condition score Authors: L.A. Zarazaga, M.C. Gatica, L. Gallego-Calvo, J.L. Guzmán PII:S0378-4320 (16) This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. Highlights Reproductive activity of bucks is reduced in spring when male effect is used.  The response to the male effect decreases when females have an inadequate food supply.  Melatonin might reduce the negative effect of decreasing body weight-condition score.  Greater fecundity, fertility and productivity were observed in gain-melatonin does.  Plasma glucose and IGF-1 concentrations could explain the better reproductive results.3 AbstractThe aim of the present work was to determine whether treatment with melatonin modifies the reproductive response of female goats experiencing increasing or decreasing body weight (BW)/body condition score (BCS) when introduced to bucks displaying springtime sexual activity. During natural anoestrus, 53 does were isolated from bucks for a period of 42 days and distributed into two groups: 1) low BW/low BCS animals (N=24) (LLg group), which were fed 1.9 times their maintenance requirements so they would experience increasing BW and BCS; and 2) high BW/high BCS animals (N=29) (HHl group), which were fed 0.4 times their maintenance requirements so they would experience decreasing BW and BCS. Half of each group was treated, or not, with melatonin (LLg+Mel N=12, HHl+Mel N=15, LLg-Mel N=12 and HHlMel N=14). On 6th May they were introduced to six males, showing natural sexual activity, fitted with marking harnesses (thus permitting the detection of oestrous activity). The ovulation rate was assessed by transrectal ultrasonography and confirmed via the plasma progesterone concentration (measured twice per week in blood samples). Plasma glucose, IGF-1 and non-esterified fatty acid concentrations were also determined, along with the conception rate, fertility, prolificacy and productivity of the does. LH concentrations and LH pulsatility were also recorded in the hours around introduction to the males. 'Oestrous plus ovulation' was observed only in does treated with melatonin. A higher conception rate and greater fertility and productivity were observed among the LLg+Mel does. These females showed higher glucose and IGF-1 concentrations after the introduction of the males. LH concentrations increased after male introduction independent of all other conditions. In conclusion, the present results show that treatment w...

show abstract

Section: Discussionsupporting

confidence: 93%

Section: Discussionmentioning

confidence: 49%

The reproductive performance of female goats treated with melatonin is not improved after introduction to bucks displaying springtime sexual activity if these does are experiencing decreasing body weight/condition score

Zarazaga

Gatica

Gallego-Calvo

et al. 2017

Animal Reproduction Science

View full text Add to dashboard Cite

show abstract

“…A numerical decrease on the mRNA level of PPARG2 in the MT of the underfed goats, compared with the respective controls and the overfed was observed in our study (Fig. 1), despite the significantly higher concentrations of NEFA which were found in their plasma (Tsiplakou et al, 2012). The discrepancy of our results with those of dairy cows maybe due to the fact that the PPARG gene expression has been examined in other tissues type than MT, since specific studies for PPARG in bovine mammary gland are lacking (Bionaz et al, 2013).…”

Section: Genessupporting

confidence: 47%

“…The full experimental design has been described with details in the paper of Tsiplakou et al (2012).…”

Section: Methodsmentioning

confidence: 99%

The effect of long term under- and over-feeding on the expression of genes related to lipid metabolism in the mammary tissue of goats

et al. 2015

Self Cite

View full text Add to dashboard Cite

“…1) despite the significantly higher concentrations of NEFA which were found in their plasma (Tsiplakou et al 2012). Nutrient restriction in dairy cows causes a concomitant increase in blood NEFA, and enhances PPARα and PPARβ/δ genes expression in liver and PPARγ expression in the hypothalamus (Kuhla et al 2011).…”

Section: Resultsmentioning

confidence: 99%

The effect of long term under- and over-feeding on the expression of genes related to lipid metabolism in mammary tissue of sheep

Tsiplakou

Flemetakis

Kouri

et al. 2014

Journal of Dairy Research

View full text Add to dashboard Cite

Milk fatty acid (FA) synthesis by the mammary gland involves expression of a large number of genes whose nutritional regulation remains poorly defined. In this study, we examined the effect of long-term under- and over-feeding on the expression of genes (acetyl Co A carboxylase, ACC; fatty acid synthetase, FAS; lipoprotein lipase, LPL; stearoyl Co A desaturase, SCD; peroxisome proliferator activated receptor γ2, PPARγ2; sterol regulatory element binding protein-1, SREBP-1c; and hormone sensitive lipase, HSL) related to FA metabolism in sheep mammary tissue (MT). Twenty-four lactating sheep were divided into three homogenous sub-groups and fed the same ration in quantities covering 70% (underfeeding), 100% (control) and 130% (overfeeding) of their energy and crude protein requirements. The results showed a significant reduction of mRNA of ACC, FAS, LPL and SCD in the MT of underfed sheep, and a significant increase on the mRNA of LPL and SREBP-1c in the MT of overfed compared with the control respectively. In conclusion, the negative, compared to positive, energy balance in sheep down-regulates ACC, FAS, LPL, SCD, SREBP-1c and PPARγ2 expression in their MT which indicates that the decrease in nutrient availability may lead to lower rates of lipid synthesis.

show abstract

The effect of long term under- and over-feeding on milk and plasma fatty acids profile and on insulin and leptin concentrations of goats

Cited by 23 publications

References 42 publications

The reproductive performance of female goats treated with melatonin is not improved after introduction to bucks displaying springtime sexual activity if these does are experiencing decreasing body weight/condition score

The reproductive performance of female goats treated with melatonin is not improved after introduction to bucks displaying springtime sexual activity if these does are experiencing decreasing body weight/condition score

The effect of long term under- and over-feeding on the expression of genes related to lipid metabolism in the mammary tissue of goats

The effect of long term under- and over-feeding on the expression of genes related to lipid metabolism in mammary tissue of sheep

Contact Info

Product

Resources

About