The Effect of Laser Power on Photothermoacoustic Imaging of Blood Containing Gold Nanoparticles and Deoxygenation using a Frequency-Domain Phased Array Probe: An In-vitro Assay

Single-walled carbon nanotubes as a photo-thermo-acoustic cancer theranostic agent: theory and proof of the concept experiment

“…Among the most examined ones are wound healing, tissue coagulation and vaporization, tissue ablation, and necrosis 1 . However, for the tissue embedded with micro-or nanoparticles (NPs) having the sharp absorption lines in the so-called therapeutic window of 650-1350 nm 2 , one can employ photothermal 3 , photothermoacoustic 4 , and photoacoustic 5 effects for treatment. Owing to their ability to target tumor tissue, as well as their capacity to be manipulated by light, NPs are perfectly suitable for theranostic cancer screening, staging, and treatment 6,7 using light in the near-infrared (NIR) tissue transparency window 2 .…”

“…Single-walled carbon nanotubes (SWCNTs) can be such a theranostics agent because their high NIR-absorptive ability 13 enables photothermal therapy 14 , which is much more specific and much less aggressive compared to conventional chemo-or radiotherapy. High specificity is, to a large extent, the result of SWCNTs' bioactivity 4 Tomsk State University, Lenin Ave. 36, Tomsk, Russia 634050. 5 Institute of Photonics, University of Eastern Finland, Yliopistokatu 7, 80100 Joensuu, Finland.…”