2018
DOI: 10.1590/1981-863720180003000083517 View full text |Buy / Rent full text
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Abstract: Several treatments for recurrent herpes labialis have been tested, including intradermal snake venom, camphor compresses, psychiatric treatments, vitamin C and other vitamin complexes. Nowadays, topical and systemic retroviral drugs such as acyclovir, valacyclovir and vadarabina are the drugs of choice. However they are only effective for symptoms minimization of existing lesions, without eliminating the virus permanently. In this study an alternative treatment with oral L-lysine is presented. This is one of t… Show more

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“… 14 The antiviral potential of l ‐Lysine may be associated with the fact that this amino acid increases the excretion of l ‐Arginine by the kidney and intestine, decreasing its concentration and consequently its action on protein synthesis by the virus, preventing replication, 14 , 21 and that the lesions do not progress to the active clinical phase, disappearing in the prodromal phase. 14 , 20 …”
Section: Discussionmentioning
“…Studies have shown a strong association of PR with human herpesviruses (HHV‐6 and HHV‐7) as an etiological factor 12 , 14 , 15 , 16 and with the suspicion of this viral involvement, therapy with antivirals such as acyclovir was indicated 15 , 17 , 18 as well as alternative therapy with l ‐Lysine amino acid 14 , 19 that showed positive results in reducing healing time as limiting the number of lesions when started at the beginning of the dermal manifestation, as soon as possible, still the first 2 weeks, in the viral multiplication phase. 14 , 19 , 20 …”
Section: Introductionmentioning
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