The effect of exercise training programs with aerobic components on C‐reactive protein, erythrocyte sedimentation rate and self‐assessed disease activity in people with ankylosing spondylitis: A systematic review and meta‐analysis

Harpham, Conrad; Harpham, Quillon; Barker, Alan R.

doi:10.1111/1756-185x.14315

Cited by 9 publications

(6 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Further, ASDAS includes the assessment of an inflammation marker. This means that proper exercise performance would affect the course of AS at least in the short‐term, as has been shown in a systematic review 28 . Measurement of BASMI scores includes objective assessment of physical metrics in AS.…”

Section: Discussionmentioning

confidence: 96%

“…This means that proper exercise performance would affect the course of AS at least in the short-term, as has been shown in a systematic review. 28 Measurement of BASMI scores includes objective assessment of physical metrics in AS. Lumbar flexion, cervical rotation, and distance markers (tragus-to-wall and intermalleolar) are components of the BASMI questionnaire.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

The effects of supervision on the outcomes of exercise training in patients with ankylosing spondylitis: A single‐blind randomized controlled trial

et al. 2023

View full text Add to dashboard Cite

Aim Exercise training is crucial for managing ankylosing spondylitis. We evaluated the effects of exercise with different levels of supervision on clinical outcomes in patients with ankylosing spondylitis. Methods We performed a single‐blind randomized controlled trial in a university outpatient clinic. Overall, 45 (31 men) patients with ankylosing spondylitis were randomly allocated to 3 groups. The mean (SD) for age and disease duration were 39.3 (9.3) and 8.4 (7.8) years. The primary outcome was chest expansion in cm, and the secondary outcomes were the index scores of 5 standard questionnaires. For each participant, adalimumab 40 mg/0.8 mL/2 wk was injected and a 3‐session exercise program per week for 1 month was prescribed. Controls received a pamphlet on the exercise program. Another group received the pamphlet and underwent a 2‐hour training session. The supervised group received the pamphlet, and the 2‐hour training, and completed the program by attending each exercise session in the clinic. Results Within‐group analysis showed significant improvement in chest expansion (P = 0.016) and all subjective or objective questionnaire scores (all P < 0.001) for the full‐supervised group. Between‐group analysis implied best outcomes for chest expansion (P = 0.046), Ankylosing Spondylitis Disease Activity Score (P < 0.001), Bath Disease Activity (P = 0.010), and Metrology (P = 0.002) Indices for ankylosing spondylitis. The group with 2‐hour training experienced an improvement in some indices, and the control group did not show significant changes in the outcomes. Conclusion We recommend the prescription of a supervised training program instead of in‐home exercises for patients with ankylosing spondylitis.

show abstract

Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

The effects of supervision on the outcomes of exercise training in patients with ankylosing spondylitis: A single‐blind randomized controlled trial

et al. 2023

View full text Add to dashboard Cite

show abstract

“…The first RCT on UPA in AS patients is the SELECT-AXIS, which showed an early and significant improvement in all the efficacy outcomes, together with a rapid and constant improvement of the patients who switched from placebo. Regarding the safety profile, the most frequent AEs were upper respiratory tract infections, rhinopharyngitis (92,93). Also the addition of a soft-tissue mobilisation to the training programme of AS patients seemed to significantly improve the levels of disease activity and the physical function of patients (94).…”

Section: Jak-inhibitorsmentioning

confidence: 99%

“…• Apremilast did not show significant efficacy in AS (89,90). • An aerobic exercise programme and soft-tissue mobilisation should be added to the individual exercise prescription of AS patients (92)(93)(94). • Home-and-workplace combined exercise could improve the work productivity of AS patients (95).…”

Section: Jak-inhibitorsmentioning

confidence: 99%

Axial spondyloarthritis: one year in review 2023

Fattorini,

Gentileschi,

Cigolini

et al. 2023

Clinical and Experimental Rheumatology

View full text Add to dashboard Cite

Axial spondyloarthritides (axSpA) are a group of systemic autoimmune diseases, characterised by an inflammatory involvement of the axial skeleton, which, in the earlier phases, cannot be detected by conventional radiology, but only by magnetic resonance imaging, thus defining the so-called non-radiographic axSpA (nr-axSpA). The initial osteitis then tends to complicate into bone reabsorption and aberrant bone deposition, which then determines the ankylosis of the axial skeleton in the latest phases of the disease. Peripheral joints may also be affected, enthesitis being its more characteristic manifestation. The radiographic form corresponds to ankylosing spondylitis which, with psoriatic arthritis, is the best-known subtype of SpA. AxSpA are rarely associated to laboratory abnormalities and are usually complicated by the presence of both extra-articular manifestations (particularly acute anterior uveitis, psoriasis and inflamatory bowel disease) and comorbidities, with a subsequent higher risk for patients of an impaired quality of life. In this paper we reviewed the literature on axSpA of 2021 and 2022 (Medline search of articles published from 1st January 2021 to 31st December 2022).

show abstract

“…In Karin's experiment, aerobic exercise was found to significantly improve fitness and reduce peripheral pain in AS patients [34]. Some researchers have also demonstrated that aerobic exercise has a significant effect on promoting the recovery of AS patients [35,36]. Meanwhile, Yoga [37], Pilates [13],…”

Section: Plos Onementioning

confidence: 99%

Effectiveness of exercise intervention in relieving symptoms of ankylosing spondylitis: A network meta-analysis

Luo,

Chen,

Yan

et al. 2024

PLoS ONE

View full text Add to dashboard Cite

Background Ankylosing spondylitis(AS) is a chronic inflammatory rheumatic disease that leads to a reduced quality of life. Exercise appears to be one of the promising modes of intervention. The aim of this study was to review the available evidence and compare the effectiveness of different exercises in relieving symptoms of AS. Methods We searched the Pubmed, WOS, EMbase, CNKI, Cochrane Library, and Scopus databases. The search has spanned from the creation of the database until September 15, 2023. We extracted the first author, year of article publication, sample information, intervention, duration of intervention, and outcome indicators from the literature that met the inclusion criteria. The Cochrane Risk Assessment Tool was used to assess the risk of bias for included studies. I² was used to judge the consistency of the included studies. Egger’s test and Begg’s test were used to judge whether there was significant publication bias. Forest plots were used to compare intervention effects and SUCRA was provided to rank the effects of the interventions. This study has been registered in PROSPERO(No. CRD42024518522). Results After screening, 10 papers matched the inclusion criteria for this study, and the total sample size of the 10 papers was 623. Upon analysis, the papers included in this study did not have significant publication bias (Begg’s Test P = 0.210) and had good consistency (P>0.05). The direct comparisons showed that Running, Pilates, Stretching, Yoga, and Tai Chi were more effective interventions than traditional therapies. The effect sizes, confidence intervals, and number of studies for each intervention are shown below: Running [MD -1.90 (95% CI -3.14,-0.66) n = 1], Pilates [MD -1.70 (95% CI -2.90,-0.51) n = 1], Stretching [MD -1.54 (95% CI -2.21,-0.88) n = 4], Yoga [MD -1.24 (95% CI -2.18,-0.30) n = 1], Tai Chi [MD -0.78 (95% CI -1.44,-0.12) n = 2], Exergame[MD -0.80 (95% CI -1.99,0.39) n = 1], Swiss balls[MD -1.07 (95% CI -2.58,0.44) n = 1]. The indirect comparisons showed that the range of effect sizes for each sport intervention intersected the null line. Based on cumulative probability, the order of effectiveness of different exercises in relieving AS symptoms is Running, Pilates, Stretching, Yoga, Tai Chi, Exergame, and Swiss ball. Conclusion Running, Pilates, Stretching, Yoga, and Tai Chi provided significant relief from AS symptoms. Exergame and Swiss ball were not statistically significant in relieving AS symptoms. There were no significant differences in the effectiveness of different exercise interventions in relieving AS symptoms. Running may have the most beneficial effect on alleviating AS symptoms.

show abstract

The effect of exercise training programs with aerobic components on C‐reactive protein, erythrocyte sedimentation rate and self‐assessed disease activity in people with ankylosing spondylitis: A systematic review and meta‐analysis

Cited by 9 publications

References 46 publications

The effects of supervision on the outcomes of exercise training in patients with ankylosing spondylitis: A single‐blind randomized controlled trial

The effects of supervision on the outcomes of exercise training in patients with ankylosing spondylitis: A single‐blind randomized controlled trial

Axial spondyloarthritis: one year in review 2023

Effectiveness of exercise intervention in relieving symptoms of ankylosing spondylitis: A network meta-analysis

Contact Info

Product

Resources

About