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Cited by 260 publications
(158 citation statements)
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“…skeletal muscle; protein turnover THE USE OF CREATINE SUPPLEMENTATION as an ergogenic aid has increased markedly, especially among athletes requiring high power outputs during so-called explosive events. In investigating the possible mechanisms for the claimed improvements in performance, many workers have reported that creatine supplementation is accompanied by a significant increase in lean body mass (1,2,4,9,14). There is evidence that the increase in muscle mass does not simply represent an increase in total body water but is mainly intracellular, suggesting that the body cell dry mass has increased (10).…”
mentioning
confidence: 99%
“…skeletal muscle; protein turnover THE USE OF CREATINE SUPPLEMENTATION as an ergogenic aid has increased markedly, especially among athletes requiring high power outputs during so-called explosive events. In investigating the possible mechanisms for the claimed improvements in performance, many workers have reported that creatine supplementation is accompanied by a significant increase in lean body mass (1,2,4,9,14). There is evidence that the increase in muscle mass does not simply represent an increase in total body water but is mainly intracellular, suggesting that the body cell dry mass has increased (10).…”
mentioning
confidence: 99%
“…ergogenic aid; osmosensing; cell signaling; cDNA microarray; realtime PCR CREATINE MONOHYDRATE (CrM) supplementation has a number of biochemical and physiological effects and enhances muscle performance in humans (89). Intracellular phosphocreatine (PCr) functions as an energy buffer to prevent ATP depletion in the skeletal muscle, especially during short-duration repetitive high-intensity exercise bouts (22,43,75,89). Following the intake of 20 g CrM/day for 4 -7 days (2, 29, 33) or 3 g CrM/day for 4 -12 wk (4,46,91,94), skeletal muscle total creatine and PCr increase by 10 -20%.…”
mentioning
confidence: 99%
“…As shown in the The results of these studies suggest that the ergogenic effects of Cr may be somewhat sport or event specific, with little or no apparent benefit for swimming sprints 10,39 or tennis stroke power or precision, 40 but with more consistent benefits associated with bench press, 2,5,15,34,55,56 leg press, 2,5,15,34,55-57 squats, 5,29,34,55 and jumping. 8,29,55,56 Performance in running sprints was improved in most, 8,14,25,29 but not all studies, 40 and inconsistent results have been observed for cycling sprint performance, with benefits observed in several studies, 7,11,15,16,47,58 while not in others. 12,17,49,52,53 Cr supplementation generally has not been associated with improvements in endurance exercise performance, 16,29,52 or a reduction in muscle damage with high-intensity exercise.…”
Section: Effects Of Creatine Supplementation On Performancementioning
confidence: 97%