The effect of acute cigarette smoke inhalation on pulmonary and systemic cysteine and glutathione redox states in the rat

Evaluation of the pulmonary effects of short-term nose-only cigarette smoke exposure in mice

“…On the other hand, it has been reported that acute (1 h) CS exposure of rats caused a significant depletion of GSH in lung. 35 Similarly, immediately following exposure by nose-only inhalation to mainstream CS (at varying doses 40, 120, 240 puffs), dose-dependent decreases in pulmonary GSH was observed in rats whereas, in guinea pigs, reductions in pulmonary GSH was observed only at the highest level of exposure, and that within three hours of exposure, GSH has returned to pre-exposure levels. 36 Ardite et al 12 reported no reduction of GSH content in guinea pig lungs three hours and 24 h following nose-only CS exposure.…”

Evaluation of the pulmonary effects of short-term nose-only cigarette smoke exposure in mice

“…On the other hand, it has been reported that acute (1 h) CS exposure of rats caused a significant depletion of GSH in lung. 35 Similarly, immediately following exposure by nose-only inhalation to mainstream CS (at varying doses 40, 120, 240 puffs), dose-dependent decreases in pulmonary GSH was observed in rats whereas, in guinea pigs, reductions in pulmonary GSH was observed only at the highest level of exposure, and that within three hours of exposure, GSH has returned to pre-exposure levels. 36 Ardite et al 12 reported no reduction of GSH content in guinea pig lungs three hours and 24 h following nose-only CS exposure.…”

Determination of oxidative stress level and some antioxidant activities in refractory epilepsy patients

“…Because GSH protects the cell from all kinds of threats against oxidative stress, it has been reported that cellular damage may occur in GSH deficient patients. The GSH level is higher in patients with prostate cancer and bladder disease 16 , 17 , 46 . In experimental rat models, it has been determined that the seizures in animals did not recur for a long time with the administration of some antioxidant agents in animals with epilepsy 47 .…”

Mycoplasma pneumoniae Infection and Environmental Tobacco Smoke Inhibit Lung Glutathione Adaptive Responses and Increase Oxidative Stress

“…We found that mice exposed to 16 weeks of ETS had increased ELF GSH steady-state levels that were blocked in the M. pneumoniae group. ETS has been shown to acutely depress ELF GSH levels, which return or rebound within 2 to 6 h (3,12,23). These changes have also been shown to correlate with the elevation of transcription factors known to regulate genes involved in GSH synthesis (51).…”

Evaluation of the pulmonary effects of short-term nose-only cigarette smoke exposure in mice

“…On the other hand, it has been reported that acute (1 h) CS exposure of rats caused a significant depletion of GSH in lung. 35 Similarly, immediately following exposure by nose-only inhalation to mainstream CS (at varying doses 40, 120, 240 puffs), dose-dependent decreases in pulmonary GSH was observed in rats whereas, in guinea pigs, reductions in pulmonary GSH was observed only at the highest level of exposure, and that within three hours of exposure, GSH has returned to pre-exposure levels. 36 Ardite et al 12 reported no reduction of GSH content in guinea pig lungs three hours and 24 h following nose-only CS exposure.…”

Determination of oxidative stress level and some antioxidant activities in refractory epilepsy patients

“…Because GSH protects the cell from all kinds of threats against oxidative stress, it has been reported that cellular damage may occur in GSH deficient patients. The GSH level is higher in patients with prostate cancer and bladder disease 16 , 17 , 46 . In experimental rat models, it has been determined that the seizures in animals did not recur for a long time with the administration of some antioxidant agents in animals with epilepsy 47 .…”

Mycoplasma pneumoniae Infection and Environmental Tobacco Smoke Inhibit Lung Glutathione Adaptive Responses and Increase Oxidative Stress

“…We found that mice exposed to 16 weeks of ETS had increased ELF GSH steady-state levels that were blocked in the M. pneumoniae group. ETS has been shown to acutely depress ELF GSH levels, which return or rebound within 2 to 6 h (3,12,23). These changes have also been shown to correlate with the elevation of transcription factors known to regulate genes involved in GSH synthesis (51).…”

Evaluation of the pulmonary effects of short-term nose-only cigarette smoke exposure in mice

“…On the other hand, it has been reported that acute (1 h) CS exposure of rats caused a significant depletion of GSH in lung. 35 Similarly, immediately following exposure by nose-only inhalation to mainstream CS (at varying doses 40, 120, 240 puffs), dose-dependent decreases in pulmonary GSH was observed in rats whereas, in guinea pigs, reductions in pulmonary GSH was observed only at the highest level of exposure, and that within three hours of exposure, GSH has returned to pre-exposure levels. 36 Ardite et al 12 reported no reduction of GSH content in guinea pig lungs three hours and 24 h following nose-only CS exposure.…”

Determination of oxidative stress level and some antioxidant activities in refractory epilepsy patients

“…Because GSH protects the cell from all kinds of threats against oxidative stress, it has been reported that cellular damage may occur in GSH deficient patients. The GSH level is higher in patients with prostate cancer and bladder disease 16 , 17 , 46 . In experimental rat models, it has been determined that the seizures in animals did not recur for a long time with the administration of some antioxidant agents in animals with epilepsy 47 .…”

Mycoplasma pneumoniae Infection and Environmental Tobacco Smoke Inhibit Lung Glutathione Adaptive Responses and Increase Oxidative Stress

“…We found that mice exposed to 16 weeks of ETS had increased ELF GSH steady-state levels that were blocked in the M. pneumoniae group. ETS has been shown to acutely depress ELF GSH levels, which return or rebound within 2 to 6 h (3,12,23). These changes have also been shown to correlate with the elevation of transcription factors known to regulate genes involved in GSH synthesis (51).…”