The effect of Acu-TENS on FEV1, six minute walk distance and dyspnoea in patients with chronic obstructive pulmonary disease: a randomised trial

Vyas, Bhavesh M; Shah, Swati; Tiwari, Hemant; Singh, Amita

doi:10.7439/ijbar.v4i7.392

Cited by 7 publications

(12 citation statements)

References 26 publications

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“…Meta-analysis revealed that the treatment group can significantly increase FEV1% predicted in patients with COPD [MD = 5.92%, 95% CI (3.43–8.41), P < 0.00001] ( Figure 5 ). The sensitivity analysis of FEV1% predicted showed that the heterogeneity was reduced ( I 2 = 0%, P = 0.56) after removing the article by Vyas et al ( 14 ). A fixed-effect model was used to analyze the other two studies, and the result for FEV1% predicted showed an improvement of 7.41% in the experimental group compared with the control group [MD = 7.41, 95% CI (5.46–9.35), P < 0.00001].…”

Section: Resultsmentioning

confidence: 95%

“…Among the included RCTs, three ( 13 , 14 , 19 ) reported FEV1% predicted as an outcome. Due to the obvious heterogeneous ( I 2 = 66%, P = 0.05), a random-effect model was used.…”

Section: Resultsmentioning

confidence: 99%

“…A total of six trials ( 12 – 14 , 17 – 19 ) reported 6-min walk distance (6MWD) as an outcome. The random-effect model was adopted according to the results of heterogeneity test ( I 2 = 62%, P = 0.02).…”

Section: Resultsmentioning

confidence: 99%

“…Among the included studies, four ( 14 , 19 – 21 ) reported dyspnea visual analog scale (DVAS) as an outcome. Because of the significant heterogeneity ( I 2 = 98%, P < 0.00001), a random-effect model was chosen.…”

Section: Resultsmentioning

confidence: 99%

“…However, subgroup analysis was not effective in reducing heterogeneity. Therefore, sensitivity analysis was performed, and the heterogeneity was reduced ( I 2 = 9%, P = 0.33) after removing the article by Vyas et al ( 14 ). A fixed-effect model was used to analyze the other three studies, and the result for DVAS showed a statistical reduction of 11.96 points in the experimental group compared with the control group [MD = −11.96, 95% CI (−12.41 to −11.51), P < 0.00001].…”

Section: Resultsmentioning

confidence: 99%

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Transcutaneous electrical nerve stimulation over acupoint for chronic obstructive pulmonary disease: A systematic review and meta-analysis

Wei

Yuan²,

Dong

et al. 2022

Front. Public Health

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BackgroundTranscutaneous electrical nerve stimulation over an acupoint (acu-TENS), a new technique applied in pulmonary rehabilitation programs, has been gradually used in the management of chronic obstructive pulmonary disease (COPD). However, the effects of acu-TENS have not been fully evaluated. Therefore, this review was conducted to assess the effects of acu-TENS on COPD.MethodsA total of seven electronic databases were searched from their inception to September 2021 for randomized controlled trials of acu-TENS for COPD. Two investigators independently performed data extraction and methodological quality assessment. Heterogeneity was examined by Cochrane χ2 and I2 tests. The source of heterogeneity was investigated by subgroup analysis or sensitivity analysis.ResultsIn our review, ten studies between 2008 and 2021 were included. The aggregated results indicated that acu-TENS showed positive effects in forced expiratory volume in 1 s (FEV1) [MD = 0.13 L, 95% CI (0.11–0.16), P < 0.00001], FEV1% predicted [MD = 5.92%, 95% CI (3.43–8.41), P < 0.00001], 6-min walk distance (6MWD) [MD = 14.68m, 95% CI (6.92–22.44), P = 0.0002], dyspnea visual analog scale (DVAS) [MD = −7.58, 95%CI (−14.33 to −0.84), P = 0.03], modified Borg scale (MBS) [MD = −0.46, 95% CI (−0.86 to −0.06), P = 0.03], and COPD assessment test (CAT) [MD = −4.25, 95% CI (−5.24 to −3.27), P < 0.00001]. Although six studies reported adverse effects, only one patient had shoulder pain after acu-TENS.ConclusionAcu-TENS seems to be effective in improving pulmonary function and health status in patients with COPD, with little effect on exercise capacity and dyspnea. However, this result should be interpreted with caution, and high-quality RCTs were needed for further verification.

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Section: Resultsmentioning

confidence: 95%

“…Among the included RCTs, three ( 13 , 14 , 19 ) reported FEV1% predicted as an outcome. Due to the obvious heterogeneous ( I 2 = 66%, P = 0.05), a random-effect model was used.…”

Section: Resultsmentioning

confidence: 99%