The Disappearing Sperms: Analysis of Reports Published Between 1980 and 2015

Sengupta, Pallav; Dutta, Sulagna; Krajewska-Kułak, Elżbieta

doi:10.1177/1557988316643383

Cited by 134 publications

(99 citation statements)

References 254 publications

(133 reference statements)

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“…Recently, Rolland et al 9 in their analysis showed 32% decline in sperm count from 1989 to 2005 9 . In our recent articles, we have also reported decline in semen volume 10 and sperm count 11 in males over past few decades.…”

Section: Introductionmentioning

confidence: 73%

“…Recent studies on male reproductive system when brought together bring conflicting evidence to the forefront regarding sperm counts with some showing significant decline while some found no change. North America, Europe and Asia were more prone to a declining trend of sperm counts over the years whereas studies based on South America and Australia do not depict such a trend 11 . However, in this present analysis a significant decline in sperm concentration has been noted in the African population.…”

Section: Data Extraction and Data Anaysismentioning

confidence: 84%

“…It reflected almost 57% decline in sperm count worldwide from 1980. It also showed that recruitment of larger population for this type of study increased predominantly after 1995 11 . In another report, we revealed a time-dependent decline of sperm concentration (r = -0.307, p = 0.02) in European men from 1965 to 2015 and an overall 32.5% decrease in mean concentration 45 .…”

Section: Data Extraction and Data Anaysismentioning

confidence: 91%

“…We also reported some link factors of declining sperm concentration worldwide 11 , but the proper correlation with a single factor is difficult to establish.…”

Section: Possible Causative Factorsmentioning

confidence: 92%

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Evidence for decreasing sperm count in African population from 1965 to 2015

Sengupta¹,

Nwagha²,

Dutta³

et al. 2017

Afr H. Sci.

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Purpose: This meta-analysis, following our previous reports those documented an overall 57% diminution in mean sperm concentration around the globe over past 35 years and 32.5% decline in past 50 years in European population, attempts to report the declining trend of sperm concentrations in African population between 1965 and 2015. Methods: In the course of retrieval of data following MOOSE guidelines and PRISMA checklist, we found a total of fourteen studies that have been conducted during that period on altering sperm concentration in the African male. Results: Following analysis of the data, a time-dependent decline of sperm concentration (r = -0.597, p = 0.02) and an overall 72.6% decrease in mean sperm concentration was noted in the past 50 years. The major matter of concern is the present mean concentration (20.38×10 6 /ml) is very near to WHO cut-off value of 2010 of 15×10 6 /ml. Several epidemic diseases, genital tract infection, pesticides and heavy metal toxicity, regular consumption of tobacco and alcohol are reported as predominant causative factors. Conclusion: This comprehensive, evidence-based meta-analysis and systematic review concisely presents the evidence of decreased sperm concentration in the African male over past 50 years with possible causative factors to serve the scientific research zone related to male reproductive health.

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Section: Introductionmentioning

confidence: 73%

Section: Data Extraction and Data Anaysismentioning

confidence: 84%

Section: Data Extraction and Data Anaysismentioning

confidence: 91%

“…We also reported some link factors of declining sperm concentration worldwide 11 , but the proper correlation with a single factor is difficult to establish.…”

Section: Possible Causative Factorsmentioning

confidence: 92%

See 2 more Smart Citations

Evidence for decreasing sperm count in African population from 1965 to 2015

Sengupta¹,

Nwagha²,

Dutta³

et al. 2017

Afr H. Sci.

Self Cite

View full text Add to dashboard Cite

show abstract

“…Sexual dysfunction in men can be explained as the failure to accomplish normal sexual intercourse, inability to respond to erectile stimuli or sustain an erection, retarded ejaculation, decreased libido, unregulated sexual behavior etc. [7]. Innumerable synthetic products are abundantly floating in the global market with quick remedial claims.…”

Section: Introductionmentioning

confidence: 99%

Medicinal herbs in the management of male infertility

Dutta¹,

Sengupta²

2018

J Pregnancy Reprod

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Male infertility can range from neurohormonal imbalances, reproductive tissue disruptions, qualitative and quantitative deterioration of semen to sexual behavioral problems. The global deterioration of male reproductive health is a major concern and the modern therapeutic approaches to combat male infertility are expensive, less accessible, have long term treatment tenure and possess various side effects. Whereas, the herbal therapies, are better positioned to offer more holistic approaches to improve male reproductive health. In Ayurvedic pharmacology, there exists a special group of herbs, classified as vajikarana or aphrodisiacs, which nourishes and stimulates the sexual tissues. This review concentrates on the Ayurvedic approach to ameliorate male reproductive health referring to some of the most important scientifically tested herbs which have been reported to accentuate male fertility by imposing either stimulating or nourishing effects on the male reproductive organs.

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Semen Quality Following Long-term Occupational Exposure to Formaldehyde in China

Wang

Yang

et al. 2022

JAMA Netw Open

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IMPORTANCEThe potential effects of long-term occupational exposure to formaldehyde (FA) on human semen quality is not clear. OBJECTIVE To assess whether long-term occupational exposure to FA is associated with semen quality. DESIGN, SETTING, AND PARTICIPANTS This population-based cohort study was conducted fromJune 1 to June 30, 2021, in Xi'an, China. Participants were adults aged 23 to 40 years who had lived in the study area for 24 months or longer. Data analysis was performed from September 1 to October 1, 2021.EXPOSURES Long-term occupational exposure to FA was measured using a formaldehyde detector, and the FA exposure index (FEI) was calculated as follows: FEI = final concentration of FA (mg/m 3 ) × work time during a workday (hour) × cumulative workdays (year). MAIN OUTCOMES AND MEASURESSemen samples were collected by masturbation after 3 to 7 days of abstinence and were then assessed by the computer-automated semen analysis system, Baso-Papanicolaou staining, and sperm-chromatin structure assay. RESULTSA total of 205 men (mean [SD] age, 29.49 [3.64] years), with 124 individuals in the FA exposure group (mean [SD] FEI , 73.72 [54.86]) and 81 age-matched controls, were included in the final analysis. Long-term personal occupational exposure to FA was significantly associated with poor semen quality. Specifically, a 1-unit increase in FEI was associated with a change of −0.

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The Disappearing Sperms: Analysis of Reports Published Between 1980 and 2015

Cited by 134 publications

References 254 publications

Evidence for decreasing sperm count in African population from 1965 to 2015

Evidence for decreasing sperm count in African population from 1965 to 2015

Medicinal herbs in the management of male infertility

Semen Quality Following Long-term Occupational Exposure to Formaldehyde in China

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