The differential effects of thalamus and basal ganglia on facial emotion recognition

Cheung, Crystal C.Y.; Lee, Tatia M.C.; Yip, James T. H.; King, Keith D.; Li, Leonard S.W.

doi:10.1016/j.bandc.2006.01.008

Cited by 40 publications

(29 citation statements)

References 34 publications

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“…In the studies that were reviewed, mean illness duration ranged from 26.5 days [39] to 23 months [43]. The majority of studies had selected patients receiving some form of medication for the treatment of stroke [31,50,53]. Even among the studies that enrolled patients who were generally receiving medication, there may be substantial ‘on-off' variation depending on the time of day and when participants last took their medication.…”

Section: Resultsmentioning

confidence: 99%

Review of Emotion Recognition in Stroke Patients

Yuvaraj

Murugappan

Norlinah

et al. 2013

Dement Geriatr Cogn Disord

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Objective: Patients suffering from stroke have a diminished ability to recognize emotions. This paper presents a review of neuropsychological studies that investigated the basic emotion processing deficits involved in individuals with interhemispheric brain (right, left) damage and normal controls, including processing mode (perception) and communication channels (facial, prosodic-intonational, lexical-verbal). Methods: An electronic search was conducted using specific keywords for studies investigating emotion recognition in brain damage patients. The PubMed database was searched until March 2012 as well as citations and reference lists. 92 potential articles were identified. Results: The findings showed that deficits in emotion perception were more frequently observed in individuals with right brain damage than those with left brain damage when processing facial, prosodic and lexical emotional stimuli. Conclusion: These findings suggest that the right hemisphere has a unique contribution in emotional processing and provide support for the right hemisphere emotion hypothesis. Significance: This robust deficit in emotion recognition has clinical significance. The extent of emotion recognition deficit in brain damage patients appears to be correlated with a variety of interpersonal difficulties such as complaints of frustration in social relations, feelings of social discomfort, desire to connect with others, feelings of social disconnection and use of controlling behaviors.

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Section: Resultsmentioning

confidence: 99%

Review of Emotion Recognition in Stroke Patients

Yuvaraj

Murugappan

Norlinah

et al. 2013

Dement Geriatr Cogn Disord

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“…With respect to the perception of facial expression, research using functional imaging revealed an important involvement of the putamen in monkey (Logothetis, Guggenberger, Peled, & Pauls, 1999) and man (Phillips et al, 1998). Lesions of the basal ganglia result in decreased recognition of emotional facial expression of anger, disgust, and fear (Cheung, Lee, Yip, King, & Li, 2006), and there is anecdotal evidence that lesions of the left putamen and insula result in impairment of recognition of the facial expression of disgust (Calder, Keane, Manes, Antoun, & Young, 2000).…”

Section: Introductionmentioning

confidence: 99%

Reduced Ventrolateral fMRI Response during Observation of Emotional Gestures Related to the Degree of Dopaminergic Impairment in Parkinson Disease

Lotze

Reimold

Heymans

et al. 2009

Journal of Cognitive Neuroscience

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Abstract& Recent findings point to a perceptive impairment of emotional facial expressions in patients diagnosed with Parkinson disease (PD). In these patients, administration of dopamine can modulate emotional facial recognition. We used fMRI to investigate differences in the functional activation in response to emotional and nonemotional gestures between PD patients and age-matched healthy controls (HC). In addition, we used PET to evaluate the striatal dopamine transporter availability (DAT) with [11 C]D-threo-methylphenidate in the patient group. Patients showed an average decrease to 26% in DAT when compared to age-corrected healthy references.Reduction in the DAT of the left putamen correlated not only with motor impairment but also with errors in emotional gesture recognition. In comparison to HC, PD patients showed a specific decrease in activation related to emotional gesture observation in the left ventrolateral prefrontal cortex (VLPFC) and the right superior temporal sulcus. Moreover, the less DAT present in the left putamen, the lower the activation in the left VLPFC. We conclude that a loss of dopaminergic neurotransmission in the putamen results in a reduction of ventrolateral prefrontal access involved in the recognition of emotional gestures. &

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“…To the authors' knowledge there were two studies published [8] [17] so far showing deficits in affect recognition on a relatively small sample size (respectively 6 and 8 patients).…”

Section: Discussionmentioning

confidence: 99%

“…Cheung et al [8] reported patients' difficulty in recognising sadness whilst Wilkos et al [17] described the difficulty in performance of Emotion Discrimination Test and Reading the Mind in the Eyes Test in thalamic impaired patients. Other studies were case reports elaborating on clinical, psychological, and behavioural changes in patients with thalamic lesions.…”

Section: Discussionmentioning

confidence: 99%

“…Cheung and colleagues [8] compare the abilities of 19 healthy controls and 38 patients with subcortical strokes (6 of which had thalamic lesions) to recognise facial expressions using Ekman's six basic emotion categories. The clinical participants perform significantly worse than the control group and those with thalamic lesions performed especially poorly at recognising sadness.…”

Section: Introductionmentioning

confidence: 99%

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Behavioural and Neurophysiological Effects of a Stroke Rehabilitation Program on Emotional Processing in Tuberothalamic Infarct—Case Study

Kucharska¹,

Wilkos²,

Roman³

et al. 2016

JBBS

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The aim of the study was to assess the neurophysiological and behavioural effects of a stroke rehabilitation involving Treatment As Usual (TAU) combined with Social Cognitive Training (SCT) in a right-handed patient suffered from tuberothalamic infarct compared to healthy controls (HCs) (n = 13). Methods: Both HCs and the patient were assessed by means of the following measures: Penn Emotion Perception Battery (ER40, EmoDiff40, PEAT40, PFMT), Reading the Mind in the Eyes Test, and Toronto Alexithymia Scale alongside clinical scales (Mini Mental State Examination, The State-Trait Anxiety Inventory, and Hamilton Depression Scale). The SCT was delivered individually for 60 minutes weekly in a 12-week program (12 sessions). The subject participated twice in a fMRI scanning session including the event-related task of implicit processing of 100% fearful expressions to detect physiological changes after TAU plus SCT and compared them with HCS who underwent the same assessment once. Results: Compared with HCs, the patient before therapy revealed lower scores in emotion recognition; particularly perception of anger was affected alongside worse performance on both emotion discrimination and acuity tests. After therapy, B.D. showed improvement in emotional processing. B.D. had less post-therapy activation maps compared with pretherapy ones and more significantly activated pre-and post-central gyrus and right cerebellum in response to fearful faces. Interestingly, no amygdala was significantly activated as the response to fearful stimuli before or after therapy was completed. Conclusions: Further research was needed to increase understanding about efficacy of SCT and the theory of neuroplasticity, thus helping rehabilitation programs.

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The differential effects of thalamus and basal ganglia on facial emotion recognition

Cited by 40 publications

References 34 publications

Review of Emotion Recognition in Stroke Patients

Review of Emotion Recognition in Stroke Patients

Reduced Ventrolateral fMRI Response during Observation of Emotional Gestures Related to the Degree of Dopaminergic Impairment in Parkinson Disease

Behavioural and Neurophysiological Effects of a Stroke Rehabilitation Program on Emotional Processing in Tuberothalamic Infarct—Case Study

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