The diagnostic accuracy of Gram stain on formalin‐fixed paraffin‐embedded sections of skin tissue in the diagnosis of bacterial skin infection
Brendan Stagg,
Erwin Foster‐Smith,
Patrick Chung Kay Tam
Abstract:Background and ObjectiveTo evaluate the sensitivity, specificity, and likelihood ratios of Gram stain on formalin‐fixed, paraffin‐embedded (GS‐FFPE) sections of skin in diagnosing bacterial skin infection.MethodsWe reviewed a retrospective series of skin specimens reported at our institution wherein histopathological assessment included Gram stain and fresh tissue was concurrently submitted for microscopy and culture. The clinicopathological correlation was the reference standard, whereby the presence of infec… Show more
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