2009
DOI: 10.1136/ard.2009.108233
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Abstract: Objective: To validate and refine two sets of candidate criteria for the classification/diagnosis of axial spondyloarthritis (SpA). Methods: All Assessment of SpondyloArthritis international Society (ASAS) members were invited to include consecutively new patients with chronic (>3 months) back pain of unknown origin that began before 45 years of age. The candidate criteria were first tested in the entire cohort of 649 patients from 25 centres, and then refined in a random selection of 40% of cases and thereaft… Show more

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Cited by 2,829 publications
(2,189 citation statements)
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“…All MRIs were read by a central reader at Synarc who reported the presence of inflammation of the SI joints, which is highly suggestive of sacroiliitis 2, 7, or the absence of SI joint inflammation. All investigators, site personnel, patients, and sponsor personnel were blinded with regard to treatment allocation.…”
Section: Methodsmentioning
confidence: 99%
See 1 more Smart Citation
“…All MRIs were read by a central reader at Synarc who reported the presence of inflammation of the SI joints, which is highly suggestive of sacroiliitis 2, 7, or the absence of SI joint inflammation. All investigators, site personnel, patients, and sponsor personnel were blinded with regard to treatment allocation.…”
Section: Methodsmentioning
confidence: 99%
“…This latter group is described as having nonradiographic axial SpA, and nonradiographic axial SpA was recently classified by the Assessment of SpondyloArthritis international Society (ASAS) as part of axial SpA 2, 7. A late diagnosis of axial SpA frequently leads to delays in treatment 8.…”
mentioning
confidence: 99%
“…These strategies were utilized to identify the early inflammatory stage of the disease in patients by focusing on the definition, classification, and diagnostic criteria of IBP and SpA, including the use of magnetic resonance imaging (MRI) for the detection of sacroiliac and vertebral inflammation, as well as the use of HLA-B27 testing. Ultimately, the Assessment of SpondyloArthritis International Society (ASAS) developed concept and classification criteria for axial SpA [11] and then for peripheral SpA [12]. At the same time, we learned about the efficacy of TNF blockers in controlling inflammation, but probably not in suppressing bone proliferation.…”
Section: Reviewmentioning
confidence: 99%
“…This recent ability to recognize u-SpA patients in this stage, thereby allowing the earlier use of TNF blockers such as etanercept or infliximab, has appeared to result in better clinical responses [69]; this improvement has had a major influence in the development of the concept of axial SpA [9]. The initial strategy was the identification of patients with axial symptoms at risk of AS [9-11]; lately, the a new strategy has evolved in focusing on identification of those with peripheral disease at risk of axial SpA [12]. …”
Section: Reviewmentioning
confidence: 99%
“…Axial SpA includes patients with or without definitive radiographic changes in the sacroiliac joints. These subpopulations are known, respectively, as ankylosing spondylitis (AS) 1 and nonradiographic axial SpA 2, 3.…”
Section: Introductionmentioning
confidence: 99%