2017
DOI: 10.18632/aging.101340
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Abstract: A specific pathogen free (SPF) barrier colony of breeding marmosets (Callithrix jacchus) was established at the Barshop Institute for Longevity and Aging Studies. Rodent and other animal models maintained as SPF barrier colonies have demonstrated improved health and lengthened lifespans enhancing the quality and repeatability of aging research. The marmosets were screened for two viruses and several bacterial pathogens prior to establishing the new SPF colony. Twelve founding animals successfully established a… Show more

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Cited by 29 publications
(46 citation statements)
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References 37 publications
(42 reference statements)
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“…The Bifidobacterium strains characterized in this study were originally isolated from fecal samples of adult common marmosets ( Callithrix jacchus ) raised in either barrier conditions at the University of Texas Health Science Center San Antonio (UTHSCSA) or a conventional colony at Southwest National Primate Research Center (SNPRC; Ross et al, ; Table ). To determine whether the high abundance of Bifidobacterium in adult marmosets was a common phenomenon, additional fecal samples from marmosets over 1 year of age were provided by the SNPRC ( n = 34), the Wisconsin National Primate Research Center (WNPRC; n = 45) and the New England Primate Research Center (NEPRC; n = 43).…”
Section: Methodsmentioning
confidence: 99%
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“…The Bifidobacterium strains characterized in this study were originally isolated from fecal samples of adult common marmosets ( Callithrix jacchus ) raised in either barrier conditions at the University of Texas Health Science Center San Antonio (UTHSCSA) or a conventional colony at Southwest National Primate Research Center (SNPRC; Ross et al, ; Table ). To determine whether the high abundance of Bifidobacterium in adult marmosets was a common phenomenon, additional fecal samples from marmosets over 1 year of age were provided by the SNPRC ( n = 34), the Wisconsin National Primate Research Center (WNPRC; n = 45) and the New England Primate Research Center (NEPRC; n = 43).…”
Section: Methodsmentioning
confidence: 99%
“…As found in humans (Stewart et al, ; Yatsunenko et al, ), the relative abundance of bifidobacteria is highly variable between individuals and populations. However, unlike humans the abundance of Bifidobacterium in marmosets can remain quite high well into adulthood (Ross et al, ). Genomic comparisons between Bifidobacterium isolated from marmosets and those isolated from humans may provide information that could be exploited in the development of probiotic strains of bifidobacteria that persist in high numbers in adult humans.…”
Section: Introductionmentioning
confidence: 99%
“…It is of note that our animals originated from at least two sources (UTHSA and SNPRC) but were housed within our animal facility for a period of at least 2 months prior to sampling. It has been noted that housing conditions can have a significant impact on hematological and blood chemistry markers (Ross et al, 2017). …”
Section: Discussionmentioning
confidence: 99%
“…Animals in this study were either born within our animal facility at UTHSA or transferred from the Southwest National Primate Research Center (SNPRC) in San Antonio TX. At UTHSA, animals were maintained in our vivarium under a modified specific pathogen-free barrier facility described in greater detail elsewhere (Ross et al, 2017). In our first cohort of animals, 23 marmosets were enrolled with 11 males and 12 females.…”
Section: Methodsmentioning
confidence: 99%
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