The detection of human herpesvirus‐8 DNA in plasma and peripheral blood mononuclear cells in adult patients with pityriasis rosea by polymerase chain reaction

Abstract

We conclude that PR is not associated with HHV-8 infection.

Comparative Study of Effectiveness of Oral Acyclovir with Oral Erythromycin in the Treatment of Pityriasis Rosea

“…22 Viral DNA of HHV7 and HHV6 is reported to be present in the peripheral blood mononuclear cells and lesional and unaffected skin of the majority of individuals with acute PR. 23 With these scientific observations, PR can be considered as a viral disease caused by HHV7 and HHV6.…”

Investigation of the Role of Inluenza Viruses A-B, Parainfluenza Viruses 1-3, Respiratory Syncytial Virus and Adenovirus in the Etiology of Pityriasis Rosea by DNA-Hybridization Method

“…A study results reported by Chuh et alin order to investigate the association of PR with human herpesvirus-8 (HHV-8) infection. As the result of the study HHV-8 DNA was found to be negative in the peripheral blood mononuclear cells and plasma of acute and convalescent specimens of all patients, and negative in all skin scrapings (11).…”

Effect of Macrolide on Pityriasis Rosea in Comparison With Acyclovir

“…As we know that pityriasis rosea has viral etiology so acyclovir has better response found in other study also. (5,6,7) Literature also says that Macrolide have anti-inflammatory effect. Apart from antibacterial effects, macrolides have effects on neutrophil function (Decreased oxidant production, apoptosis) and on the production of cytokines involved in the inflammation cascade (Decreased production of IL-1, IL- 6, IL-8, and TNF and increased production of IL-10 and, possibly, IL-4).…”